Flupred Eye Drops
Flupred (prednisolone acetate 1%) — high-potency topical corticosteroid for uveitis, post-op inflammation, allergic conjunctivitis and dry-eye flares. IOP monitoring after 2 wk.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Flupred Eye Drops?
Flupred Eye Drops is Prednisolone acetate 1%, a high-potency topical corticosteroid for ocular inflammation — uveitis, post-operative inflammation, allergic conjunctivitis, and dry-eye flares. Used 2–8 times daily depending on severity. Monitor IOP if used > 2 weeks.
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Flupred Eye Drops is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy — if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.
What is Flupred Eye Drops?
Flupred Eye Drops is manufactured by Sun Pharma and contains Prednisolone acetate 1% as a sterile ophthalmic solution or suspension. Prednisolone acetate is the standard high-potency topical steroid — strong anti-inflammatory effect at the cost of higher IOP-elevation risk.
How It Works
Prednisolone acetate binds intracellular glucocorticoid receptors, suppressing transcription of pro-inflammatory cytokines, chemokines, and leukocyte adhesion molecules. The result is decreased redness, swelling, pain, and immune-cell infiltration.
Indications
- Anterior uveitis (iritis, iridocyclitis)
- Post-operative inflammation after cataract, glaucoma, corneal, or refractive surgery
- Severe allergic conjunctivitis — when antihistamines and mast-cell stabilisers are inadequate
- Vernal keratoconjunctivitis
- Dry-eye flares — short pulse of low-potency steroid alongside cyclosporine initiation
- Episcleritis, scleritis (specialist setting)
- Corneal graft rejection (specialist)
Dosing
Highly variable by indication and severity. Typical ranges:
- Severe uveitis: 1–2 drops every 1–2 hours during waking, tapered over weeks
- Post-cataract: QID for 1 week, TID week 2, BID week 3, OD week 4
- Allergic flare / dry-eye flare: 4 times daily for 2–4 weeks
Always follow your ophthalmologist’s specific tapering schedule. Sudden stop after long use can cause rebound inflammation.
Side Effects
Local: stinging on instillation, blurred vision (especially with suspensions — shake well), elevated IOP (steroid response), posterior subcapsular cataract with chronic use, secondary ocular infection (bacterial, viral, fungal), delayed wound healing, mydriasis, ptosis (rare).
Systemic (rare with topical): Cushingoid features, HPA axis suppression — extremely rare from eye drops alone.
Warnings & Contraindications
- Active herpes simplex keratitis — absolute
- Active fungal keratitis — absolute
- Vaccinia, varicella, mycobacterial keratitis — absolute
- Untreated bacterial infection (without antibiotic cover) — relative
- Glaucoma history — high-IOP-risk; prefer loteprednol
- Children — close monitoring; cataract risk higher
- Pregnancy / breastfeeding — discuss; topical absorption minimal
- Contact-lens wearers — remove during treatment
Storage
Store at 15–25°C protected from light. Shake well before each use (prednisolone acetate is a suspension). Discard 28 days after first opening.
Frequently Asked Questions
When is Flupred Eye Drops the right choice?
When strong anti-inflammatory effect is needed — moderate-to-severe uveitis, post-cataract surgery, severe allergic flare. Not first-line for mild dry eye or chronic prophylaxis because of higher IOP risk.
What is steroid response?
Genetic predisposition to develop elevated IOP on topical steroids. About 1/3 of the population. Onset typically 2+ weeks. Have IOP checked if you use any topical steroid for more than 2 weeks.
How long can I use Flupred Eye Drops?
Acute courses: 2–4 weeks with taper. Chronic use needs ophthalmology supervision with regular IOP and lens checks. Loteprednol is preferred for any course beyond 4 weeks.
Why must I avoid Flupred Eye Drops for herpes?
Herpes simplex keratitis can devastate the cornea when steroids are added without antiviral cover. The dendritic ulcer can extend into geographic ulcer, stromal disease, or endothelial keratitis — leading to permanent vision loss. Always confirm cause before starting.
Can Flupred Eye Drops cause cataract?
Yes — chronic use causes posterior subcapsular cataract, especially in children and after months-to-years of continuous therapy. Limit duration; switch to loteprednol or NSAIDs where possible.
Is Flupred Eye Drops safe in pregnancy?
Topical absorption is minimal. Generally acceptable when clearly indicated. Discuss with your prescriber.
What about contact lenses?
Stop lenses during treatment — preservatives and steroid-mediated immunosuppression both increase risk of microbial keratitis.
What if my vision worsens during treatment?
Same-day ophthalmology review. Possibilities: missed herpetic disease, fungal infection, steroid IOP rise, or corneal complication.
What is the difference between prednisolone, fluorometholone, and loteprednol?
Prednisolone acetate: most potent, highest IOP risk. Fluorometholone: mid-potency, lower IOP risk. Loteprednol: ‘soft’ steroid metabolised quickly in the eye, lowest IOP risk — preferred for chronic use. All require monitoring beyond 2 weeks.
Can I taper Flupred Eye Drops suddenly?
No — sudden stop can cause rebound inflammation. Always follow the prescribed taper schedule.
Other Eye-Care Medications
Customers viewing this product also consider these alternatives in our Eye Care range:
- Pred Forte (prednisolone acetate)
- FML Eye Drop (fluorometholone)
- Lotepred Eye Drop (loteprednol)
- Acular LS (ketorolac)
- Megabrom (bromfenac)
Medical Disclaimer
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Strength | 0.05% w/v 5 ml |
|---|---|
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