Fml Eye Drop
FML (fluorometholone 0.1%) — low-potency topical corticosteroid for allergic conjunctivitis and mild post-op inflammation. Lower IOP-spike risk than prednisolone acetate.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is FML Eye Drop?
FML Eye Drop is Fluorometholone 0.1%, a low-potency topical corticosteroid for ocular inflammation — uveitis, post-operative inflammation, allergic conjunctivitis, and dry-eye flares. Used 2–8 times daily depending on severity. Monitor IOP if used > 2 weeks.
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What is FML Eye Drop?
FML Eye Drop is manufactured by Allergan and contains Fluorometholone 0.1% as a sterile ophthalmic solution or suspension. Fluorometholone is a low-potency steroid with reduced IOP risk — the preferred steroid for chronic mild-moderate inflammation such as allergy and dry-eye flares.
How It Works
Fluorometholone binds intracellular glucocorticoid receptors, suppressing transcription of pro-inflammatory cytokines, chemokines, and leukocyte adhesion molecules. The result is decreased redness, swelling, pain, and immune-cell infiltration.
Indications
- Anterior uveitis (iritis, iridocyclitis)
- Post-operative inflammation after cataract, glaucoma, corneal, or refractive surgery
- Severe allergic conjunctivitis — when antihistamines and mast-cell stabilisers are inadequate
- Vernal keratoconjunctivitis
- Dry-eye flares — short pulse of low-potency steroid alongside cyclosporine initiation
- Episcleritis, scleritis (specialist setting)
- Corneal graft rejection (specialist)
Dosing
Highly variable by indication and severity. Typical ranges:
- Severe uveitis: 1–2 drops every 1–2 hours during waking, tapered over weeks
- Post-cataract: QID for 1 week, TID week 2, BID week 3, OD week 4
- Allergic flare / dry-eye flare: 4 times daily for 2–4 weeks
Always follow your ophthalmologist’s specific tapering schedule. Sudden stop after long use can cause rebound inflammation.
Side Effects
Local: stinging on instillation, blurred vision (especially with suspensions — shake well), elevated IOP (steroid response), posterior subcapsular cataract with chronic use, secondary ocular infection (bacterial, viral, fungal), delayed wound healing, mydriasis, ptosis (rare).
Systemic (rare with topical): Cushingoid features, HPA axis suppression — extremely rare from eye drops alone.
Warnings & Contraindications
- Active herpes simplex keratitis — absolute
- Active fungal keratitis — absolute
- Vaccinia, varicella, mycobacterial keratitis — absolute
- Untreated bacterial infection (without antibiotic cover) — relative
- Glaucoma history — high-IOP-risk; prefer loteprednol
- Children — close monitoring; cataract risk higher
- Pregnancy / breastfeeding — discuss; topical absorption minimal
- Contact-lens wearers — remove during treatment
Storage
Store at 15–25°C protected from light. Shake well before each use if labelled as suspension. Discard 28 days after first opening.
Frequently Asked Questions
When is FML Eye Drop the right choice?
When mild-to-moderate inflammation needs control with lower IOP risk — chronic allergic conjunctivitis, mild post-operative inflammation, dry-eye flares.
What is steroid response?
Genetic predisposition to develop elevated IOP on topical steroids. About 1/3 of the population. Onset typically 2+ weeks. Have IOP checked if you use any topical steroid for more than 2 weeks.
How long can I use FML Eye Drop?
Acute courses: 2–4 weeks with taper. Chronic use needs ophthalmology supervision with regular IOP and lens checks. Loteprednol is preferred for any course beyond 4 weeks.
Why must I avoid FML Eye Drop for herpes?
Herpes simplex keratitis can devastate the cornea when steroids are added without antiviral cover. The dendritic ulcer can extend into geographic ulcer, stromal disease, or endothelial keratitis — leading to permanent vision loss. Always confirm cause before starting.
Can FML Eye Drop cause cataract?
Yes — chronic use causes posterior subcapsular cataract, especially in children and after months-to-years of continuous therapy. Limit duration; switch to loteprednol or NSAIDs where possible.
Is FML Eye Drop safe in pregnancy?
Topical absorption is minimal. Generally acceptable when clearly indicated. Discuss with your prescriber.
What about contact lenses?
Stop lenses during treatment — preservatives and steroid-mediated immunosuppression both increase risk of microbial keratitis.
What if my vision worsens during treatment?
Same-day ophthalmology review. Possibilities: missed herpetic disease, fungal infection, steroid IOP rise, or corneal complication.
What is the difference between prednisolone, fluorometholone, and loteprednol?
Prednisolone acetate: most potent, highest IOP risk. Fluorometholone: mid-potency, lower IOP risk. Loteprednol: ‘soft’ steroid metabolised quickly in the eye, lowest IOP risk — preferred for chronic use. All require monitoring beyond 2 weeks.
Can I taper FML Eye Drop suddenly?
No — sudden stop can cause rebound inflammation. Always follow the prescribed taper schedule.
Other Eye-Care Medications
Customers viewing this product also consider these alternatives in our Eye Care range:
- Pred Forte (prednisolone acetate)
- FML Eye Drop (fluorometholone)
- Lotepred Eye Drop (loteprednol)
- Acular LS (ketorolac)
- Megabrom (bromfenac)
Medical Disclaimer
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Strength | 0.1% (5 ml ) |
|---|---|
| Quantity | 1 Bottle/s, 3 Bottle/s, 6 Bottle/s |
| Pharma Form | Eye Drop/s |
| Manufacturer | Allergan |
| Treatment | Inflammation of the eye |
| Generic Brand | Fluorometholone |
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