⚡ Quick Answer — What is Asthalin Syrup?
Asthalin Syrup περιέχει salbutamol (known as albuterol in the United States), a short-acting beta-2 agonist (SABA) that relaxes bronchial smooth muscle to relieve breathlessness, wheezing, and chest tightness in asthma και chronic obstructive pulmonary disease (COPD). Asthalin Syrup is a oral syrup from Cipla. Onset of bronchodilation is 15–30 minutes and effect lasts 4–6 ώρες. Asthalin Syrup is a reliever (rescue) medication, not a controller — needing it more than 3× per week means underlying asthma is not controlled and a preventer (ICS or ICS-LABA) needs stepping up.
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What Is Asthalin Syrup?
Asthalin Syrup is a oral syrup manufactured by Cipla at WHO-GMP certified facilities. Each syrup delivers 2 mg / 5 ml of salbutamol (the international generic name is albuterol). salbutamol is on the WHO List of Essential Medicines and is the world’s most-used reliever medication for asthma and reversible airflow obstruction.
How Does Asthalin Syrup Work?
salbutamol selectively activates beta-2 adrenergic receptors on the smooth muscle that rings the bronchial airways. Receptor activation raises intracellular cyclic AMP, smooth muscle relaxes, and the airway lumen widens — this is bronchodilation. Bronchodilation begins within 15–30 minutes, peaks at 30–90 minutes, and lasts 4–6 ώρες. salbutamol also modestly inhibits mast-cell mediator release, reduces plasma exudation from airway capillaries, and improves mucociliary clearance.
Selectivity is dose-dependent: at therapeutic doses, β2 effects predominate; at higher systemic doses (oral tablets, repeated nebulisation), spillover onto β1 receptors causes tachycardia and palpitations, and onto β2 receptors elsewhere causes tremor and hypokalaemia.
Χρήσεις και ενδείξεις
- Acute asthma exacerbations — first-line reliever (rescue) inhaler/nebulisation
- Chronic obstructive pulmonary disease (COPD) — symptomatic relief of acute breathlessness and exercise dyspnoea
- Exercise-induced bronchoconstriction — inhaled 15–30 minutes before exercise
- Bronchospasm with allergen, cold air, or viral exposure
- Anaphylaxis with bronchospasm — adjunct to adrenaline
- Hyperkalaemia (off-label) — nebulised salbutamol drives K⁺ intracellularly
Σημαντικό: Asthalin Syrup is a reliever, not a controller. It does not reduce underlying airway inflammation. Patients using more than the equivalent of one SABA canister per month, or needing a SABA more than three days per week outside of exercise pre-dosing, have poorly-controlled asthma and require step-up to inhaled corticosteroid (ICS) or ICS-LABA combination therapy.
Asthalin Syrup Dosage
| Age | Dose | Συχνότητα |
|---|---|---|
| Adults & children >12 yr | 5–10 ml (2–4 mg) | Three to four times daily |
| Children 6–12 yr | 5 ml (2 mg) | Three to four times daily |
| Children 2–6 yr | 2.5–5 ml (1–2 mg) | Three to four times daily |
| Children <2 yr | Specialist supervision | 0.1 mg/kg up to 4× daily |
How to Use Asthalin Syrup Properly
- Shake the bottle well before each use.
- Use the supplied measuring spoon or oral syringe — household teaspoons are inaccurate.
- Give before food if vomiting is a concern; otherwise either way.
- Space doses at least 4 hours apart.
- Discard the bottle 28 days after first opening or by the printed expiry, whichever comes first.
- If the child vomits within 15 minutes of a dose, repeat once; if it happens repeatedly, contact a doctor.
Side Effects of Asthalin Syrup
Common (dose-related, settle within 30–60 minutes):
- Fine tremor, especially of the hands
- Palpitations or increased heart rate (typically 10–20 bpm rise)
- Κεφαλαλγία
- Dry mouth, throat irritation
- Muscle cramps
- Hyperactivity or agitation in young children
Less common:
- Hypokalaemia — especially with high repeat doses, worsened by theophylline, steroids or loop diuretics
- Mild hyperglycaemia
- Insomnia if dosed late evening
- Lactic acidosis with very high continuous nebulised doses (rare)
Serious (stop and seek emergency help):
- Severe allergic reaction / angio-oedema / anaphylaxis
- Paradoxical bronchospasm — worsening wheeze immediately after dose
- Cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia)
- Severe hypokalaemia with arrhythmia or muscle weakness
Προειδοποιήσεις και προφυλάξεις
- Frequent {$brand} use = poor asthma control. Needing a reliever more than 3 days per week (excluding exercise pre-dosing) means the underlying disease is not managed. Step up ICS-based controller therapy.
- Carry your reliever with you — many fatal asthma attacks happen when the inhaler is at home or expired.
- Cardiovascular disease: use cautiously in severe coronary artery disease, arrhythmias, hyperthyroidism, or severe heart failure.
- Diabetes: monitor glucose with repeat high doses.
- Pregnancy and breastfeeding: salbutamol is used at the lowest effective dose. Uncontrolled asthma is more dangerous to mother and fetus than the drug itself.
- Severe attack red flags (call emergency services): no relief 10 min after a full dose, peak flow <50% of personal best, difficulty speaking in full sentences, blue lips or drowsiness.
Contraindications
- Known hypersensitivity to salbutamol or any formulation excipient
- Tachyarrhythmias (uncontrolled) — relative contraindication
- Phaeochromocytoma — relative contraindication
- Hypertrophic obstructive cardiomyopathy — caution
Αλληλεπιδράσεις Φαρμάκων
| Interacting drug | Effect | What to do |
|---|---|---|
| Non-selective beta-blockers (propranolol, timolol drops) | Block β2 effect — can precipitate severe bronchospasm | Avoid; switch to cardioselective beta-blocker if essential |
| Loop or thiazide diuretics | Additive hypokalaemia | Monitor serum potassium with high doses |
| Systemic corticosteroids | Additive hypokalaemia + hyperglycaemia | Monitor electrolytes and glucose |
| Theophylline / aminophylline | Additive tachycardia and hypokalaemia | Monitor heart rate and potassium |
| MAOIs and tricyclic antidepressants | Potentiate cardiovascular effects | Caution — monitor BP/HR |
| Digoxin | Hypokalaemia increases digoxin toxicity risk | Monitor potassium; check digoxin level if symptomatic |
Storage
- Store below 25°C in a cool, dry place away from direct sunlight.
- Keep in original packaging until use to protect from moisture and light.
- Do not use after the expiry date printed on the strip.
- Keep out of reach of children.
Σχετικές Εναλλακτικές Λύσεις στο MedsBase
- Asthalin Respules — salbutamol nebuliser solution
- Budecort Inhaler — budesonide ICS preventer
- Foracort Inhaler — budesonide + formoterol ICS-LABA
- Seretide Accuhaler — fluticasone + salmeterol ICS-LABA
- Duolin Inhaler — salbutamol + ipratropium combo reliever
Συχνές Ερωτήσεις
Why give a child syrup instead of an inhaler?
In infants and toddlers who cannot reliably use even a spacer + mask, oral syrup is a practical alternative. Once a child is old enough to tolerate a face-mask spacer (usually from 6–12 months in most paediatric guidelines), inhaled salbutamol gives better symptom control with fewer systemic effects.
How long does Asthalin Syrup take to work?
About 15–30 minutes for onset, peak at 1–2 hours, total duration 4–6 hours.
Can I add Asthalin Syrup to milk or juice?
Yes for compliance, but the dose must still be measured precisely from the bottle first. Do not pre-mix into the whole bottle of juice.
My child becomes hyperactive after a dose — is this normal?
Yes, hyperactivity, restlessness, and trouble settling at night are common β2 effects in children. They settle as the dose wears off. Persistent insomnia warrants dose timing review (avoid evening doses) or switch to inhaled.
Is sugar-free Asthalin Syrup available?
Cipla makes both regular and sugar-free formulations. Check the bottle label or ask your pharmacist if dental concerns or diabetes are a factor.
Can adults take Asthalin Syrup?
Yes — 5–10 ml three to four times daily. Most adults will do better with an inhaler unless they cannot coordinate one.
What if a dose is missed?
Give it as soon as you remember unless the next dose is due. Never double up.
How is the dose calculated by weight?
For children <2 yr, the usual paediatric guideline is 0.1 mg/kg per dose (= 0.25 ml/kg of the 2 mg/5 ml syrup), three to four times daily under medical supervision.
Does Asthalin Syrup contain alcohol?
Standard Cipla Asthalin Syrup is alcohol-free. Always check the label if this is a concern (Muslim patients, alcohol-sensitive children).
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