Lupimeb

📦 Jokainen tilaus on katettuna meidän Reshipment Assurance Policy -politiikkamme piiriin — jos lähetyksesi ei saavu 20 arkipäivässä, lähetämme uuden.

Miksi tilata MedsBasesta

Geneeriset lääkkeemme on hankittu WHO-GMP sertifioiduilta valmistajilta ja toimitettu maailmanlaajuisesti hienotunteisessa, neutraalissa pakkauksessa — lääkkeen nimeä ei ole pakkauksen ulkopuolella. Korttimaksut käsitellään säädeltyjen maksunvälittäjien kautta (tilisiirtojen kuvaukset sisältävät säädellyn korttimaksun käsittelijän — ei koskaan “MedsBase” tai lääkkeen nimeä). Kryptovaluutat ja SEPA-pankkisiirrot hyväksytään myös. Jokainen tilaus on turvattu meidän Reshipment Assurance Policy -takuuohjelmalla.

What is Lupimeb?

Lupimeb is mebendazole 100 mg chewable from Lupin. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.

Toimintamekanismi

Mebendazole binds β-tubuliiniin in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores — the worm starves over 2–3 days. Mebendazole’s oral bioavailability is very low (< 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.

Lupimeb indications and dose

Tablets can be chewed, swallowed whole, or crushed and mixed with food.

Sivuvaikutukset

• Yleisiä: mild abdominal pain, transient diarrhoea, flatulence as worms pass
• Vähemmän yleisiä: headache, dizziness, mild rash
• Harvinainen: reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)
• Very rare: Stevens-Johnson syndrome, toxic epidermal necrolysis

Lääkevuorovaikutukset

• Simetidiini — raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites
• Phenytoin, carbamazepine, rifampicin — reduce mebendazole levels (CYP induction)
• Metronidazole — case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible

Käyttökiellot

• Hypersensitivity to mebendazole or other benzimidazoles
• Children < 1 year
• First trimester of pregnancy
• Vakava maksatoimintavajaus

Säilytys

Store Lupimeb below 30°C in the original blister, away from light and moisture.

Miksi tilata MedsBasesta

Lupimeb is supplied from a WHO-GMP sertifioitu valmistaja, pakattu huomaamattomasti, ja lähetetään maailmanlaajuisesti. Jokainen tilaus on katettu Reshipment Assurance Policy -politiikkamme piiriin — et koskaan joudu maksamaan kadonneesta lähetystä.

Usein Kysytyt Kysymykset

Can I just take one tablet?

For pinworm, yes — one 100 mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100 mg twice daily for 3 days.

Do I need to fast before Lupimeb?

No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.

Can my child chew Lupimeb?

Yes — the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).

How is mebendazole different from albendazole?

Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.

Will Lupimeb treat tapeworm?

Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.

How long until the worms are gone?

Adult worms are paralysed within 24–48 hours and pass in faeces over the following 3–5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1–2 weeks.

Is Lupimeb safe in pregnancy?

Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden — discuss with a clinician.

Can I drink alcohol with Lupimeb?

There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.

Does Lupimeb treat lice or scabies?

No. Mebendazole has no activity against ectoparasites — use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.

Should I retest after treatment?

For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2–4 weeks after treatment.

Patients seeking extended parasite coverage beyond Lupimeb (mebendazole 100 mg) may consider Wormentel (fenbendazole 222 / 500 mg) as a fenbendazole alternative in the same benzimidazole class but with a broader organism spectrum covering Giardia, tapeworm, and Trichinella.

Muut loisintatorjunta-aineet

• Mebex (mebendatsoli 100 mg)
• Lupimeb (mebendazole 100 mg)
• ABD 400 (albendatsoli 400 mg)
• Nemocid (pyranteli pamaatti)
• Iverheal (ivermectin)

Lisävaihtoehtoja hankakäärmepotilaiden hoidossa

Luokiteltu MedsBase-tilausmäärän mukaan — mitä muut asiakkaat tässä kategoriassa valitsevat.

Iverheal

US$36.00 – US$699.00Hinta-alue: US$36.00 - US$699.00

Ivimec

US$36.00 – US$575.00Hinta-alue: US$36.00 - US$575.00

Prazinec

US$11.00 – US$56.00Hinta-alue: US$11.00 - US$56.00

ABD 400 (Albendazole)

US$27.00 – US$122.00Hinta-alue: US$27.00 - US$122.00