Clocip

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• WHO-GMP certified manufacturer — sourced from a regulated facility, finished pack with batch number and expiry.
• Discreet packaging — plain envelope, no medication name on the outside.
• Worldwide shipping to most countries with Reshipment Assurance.
• Loyalty points — 1 point per $1 spent (excludes peptides/shipping); 100 points = $5 off your next order.

Uses

Clocip (clotrimazole 1% w/w cream, Cipla) is a broad-spectrum topical antifungal. It covers all the common skin and mucosal fungi: dermatophytes (Trichophyton, Epidermophyton, Microsporum), yeasts (Candida albicans and most non-albicans species), and Malassezia (the cause of pityriasis versicolor and seborrhoeic dermatitis).

How to apply

• Wash and dry the affected skin thoroughly — fungi thrive in moisture, so drying is half the treatment.
• Apply a thin layer of cream and rub in gently. Cover the visible lesion plus 1–2 cm of healthy-looking surrounding skin.
• Wash hands after application (unless treating the hands).
• Continue treatment for at least 1 week after symptoms have resolved — stopping early is the commonest cause of relapse.
• If no improvement after 2 weeks of correct use, reconsider the diagnosis (it may be eczema, psoriasis, contact dermatitis, or a resistant organism).

How it works

Clotrimazole inhibits fungal CYP51 (lanosterol 14-α-demethylase), blocking conversion of lanosterol to ergosterol — the principal sterol in fungal cell membranes. The resulting ergosterol-poor membrane becomes permeable and the fungal cell loses integrity. Topical application delivers high local concentrations to skin while systemic absorption remains negligible (< 0.5% from intact skin) — this is why topical clotrimazole is safe in pregnancy.

Side effects

• Generally well-tolerated.
• Common (5–10%): mild burning or stinging at the application site, transient erythema, dryness or peeling.
• Uncommon: contact dermatitis (true allergy to clotrimazole or vehicle), urticaria.
• If severe burning, weeping, or worsening rash develops, stop and reconsider — could be contact allergy or wrong diagnosis (eczema mistaken for tinea).

Drug interactions

Negligible systemic interactions due to minimal absorption. Avoid concurrent topical corticosteroids unless specifically prescribed — combination products (clotrimazole + betamethasone) are sometimes used short-term for inflamed dermatophyte infections but the steroid can mask the appearance of fungal infection if used alone, and prolonged use causes skin atrophy.

Pregnancy & breastfeeding

Topical clotrimazole is the preferred topical antifungal in pregnancy and breastfeeding — minimal systemic absorption, decades of safety data. For vaginal candidiasis in pregnancy, intravaginal clotrimazole pessaries are first-line (safer than oral fluconazole, which is avoided in the first trimester).

Frequently Asked Questions

How quickly will my athlete’s foot get better?

Itching usually settles within 3–7 days. Visible scaling and redness improve over 2 weeks. Continue treatment for 1 week after symptoms resolve to prevent relapse — stopping early is the main reason fungal infections come back.

Can I use clotrimazole on my face?

Yes for fungal skin infection (e.g. tinea faciei, pityriasis versicolor). Avoid the eyes. Many ‘red itchy face’ presentations are actually seborrhoeic dermatitis or rosacea, not fungal — if there’s no improvement in 2 weeks, see a clinician.

Is Clocip the same as Canesten?

Yes — Canesten is the original Bayer brand of clotrimazole. Clocip contains the same active ingredient (clotrimazole 1%), manufactured by Cipla under WHO-GMP. Bioequivalent.

Should I cover the area with a plaster?

No — keep the area open to air. Fungi thrive in warm moist environments; occlusive dressings encourage fungal growth and can cause maceration. For toe-web tinea, sleep with a thin gauze between toes if needed but do not seal.

My nappy rash isn’t getting better — should I use clotrimazole?

Persistent nappy rash with bright red satellite spots at the edges is often Candida and responds to clotrimazole 2–3× daily. If the rash is uniform and dry, plain barrier cream is more appropriate. If no improvement in 1 week, see a doctor.

Can I use clotrimazole and a steroid cream together?

Combination products (clotrimazole + hydrocortisone, or + betamethasone) reduce inflammation faster but should be used short-term only (< 2 weeks). Steroid alone on a fungal infection makes it worse — ‘tinea incognito’.

Why does the skin still look discoloured even after the rash clears?

For pityriasis versicolor especially, the white or brown patches can persist for weeks to months after the fungus is killed. Pigment recovery happens with sun exposure. The infection is gone — keep using sunscreen and the colour will normalise.

Is clotrimazole safe in pregnancy?

Yes — topical clotrimazole has decades of safety data in pregnancy and is the preferred topical antifungal. Intravaginal clotrimazole pessaries are first-line for vaginal candidiasis in pregnancy (safer than oral fluconazole, which is avoided in the first trimester).

Can my partner catch tinea / Candida from me?

Tinea (athlete’s foot, jock itch, ringworm) is mildly contagious — share a towel, share a fungus. Candida balanitis can pass between partners. Treat both partners if symptomatic, wash bedding, and don’t share towels until cleared.

What if clotrimazole isn’t working?

Reconsider the diagnosis after 2 weeks of correct twice-daily application. Eczema, psoriasis, contact dermatitis, and lichen planus can all mimic tinea. If genuinely fungal but unresponsive, consider a more potent topical (terbinafine cream) or oral therapy (terbinafine for dermatophytes; fluconazole for Candida).

Storage

Store at 15–25 °C, away from heat and direct sunlight. Replace the cap tightly after use. Keep out of reach of children. Discard 6 months after first opening.

If Clocip (clotrimazole 1 % cream) is not clearing a tinea pedis or cutaneous candida infection within two weeks, switching imidazole class to Micogel Cream (miconazole 2 % topical) is a reasonable next step before escalating to oral therapy.

Other Antifungal Medications you may be interested in

If Clocip is unavailable, here are alternatives — same molecule from a different manufacturer, plus other broad-spectrum topical antifungals.

• Terbicip Cream (terbinafine 1%) — Most potent topical for athlete’s foot; 1–2 week course.
• Lulibet XL Cream (luliconazole 1%) — Newer-generation imidazole; 1-week course for cruris/corporis.
• Clocip (clotrimazole 1% cream) — Broad-spectrum, OTC standard, safe in pregnancy.
• Keto Cream (ketoconazole 2%) — Best for seborrhoeic dermatitis (Malassezia).
• Zimig (oral terbinafine 250 mg) — Step up to oral when topical fails or for extensive disease.

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