Iotim Eye Drops
Iotim (timolol maleate 0.5%) — non-selective beta-blocker eye drop for open-angle glaucoma. Twice-daily IOP control. Contraindicated in asthma and severe COPD.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Iotim Eye Drops?
Iotim Eye Drops is Timolol maleate 0.5%, a topical beta-blocker eye drop that lowers eye pressure 20–25% in glaucoma by reducing aqueous humour production. Non-selective — contraindicated in asthma, severe COPD, sinus bradycardia, and AV block. Used 1–2 times daily.
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Why order from MedsBase
Iotim Eye Drops is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy — if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.
What is Iotim Eye Drops?
Iotim Eye Drops is manufactured by FDC and contains Timolol maleate 0.5% as a sterile ophthalmic solution. Timolol is a non-selective beta-blocker that blocks both beta-1 (cardiac) and beta-2 (bronchial) adrenergic receptors. It is one of the oldest and most studied IOP-lowering drugs.
How It Works
Timolol maleate blocks beta-adrenergic receptors on the ciliary epithelium, reducing the rate of aqueous humour secretion. This decreases the volume of fluid in the anterior chamber and lowers IOP by approximately 20–25%. Unlike prostaglandin analogs (which work on outflow), beta-blockers work on the production side of the equation — making them additive with prostaglandins and CAIs.
Indications & Dosing
| Indication | Dose |
|---|---|
| Open-angle glaucoma | 1 drop in affected eye(s) twice daily (morning and evening) |
| Ocular hypertension | 1 drop twice daily — same as POAG |
| Once-daily formulations (timolol XE / gel-forming) | Different bottles — follow label |
Side Effects
Local (eye): stinging on instillation, dry eye, blurred vision, conjunctival hyperaemia, corneal anaesthesia (rare).
Systemic (from absorption): bradycardia, hypotension, fatigue, depression, decreased exercise tolerance, decreased libido, bronchospasm in reactive-airway patients, masking of hypoglycaemia signs in diabetics.
Warnings & Contraindications
- Asthma, severe COPD — absolute contraindications
- Sinus bradycardia, second/third-degree AV block, decompensated heart failure
- Concurrent oral beta-blockers — additive bradycardia
- Pregnancy / breastfeeding — discuss with specialist
- Diabetes — beta-blockade can mask tachycardia of hypoglycaemia
- Severe peripheral vascular disease — relative contraindication
Storage
Store at room temperature 15–25°C protected from light. Do not freeze. Discard 28 days after first opening.
Frequently Asked Questions
How quickly does Iotim Eye Drops lower eye pressure?
IOP reduction begins within 30 minutes of the first dose and reaches near-maximum effect at 1–2 hours. Steady-state IOP is reached at 4 weeks.
Can I use Iotim Eye Drops with my heart medication?
Tell your prescriber if you take oral beta-blockers, calcium-channel blockers (diltiazem, verapamil), or digoxin. The combination can produce additive bradycardia and conduction blocks.
Is Iotim Eye Drops safe in asthma?
No — timolol is contraindicated in asthma, even when applied to the eye. Switch to betaxolol or a different drug class such as a prostaglandin analog or alpha-2 agonist.
What is the long-term tachyphylaxis effect?
Some patients show reduced response after weeks to months of continuous use (‘long-term drift’). If IOP drifts back up, your ophthalmologist may add a second agent rather than increase the dose.
Can I take Iotim Eye Drops if I'm a diabetic?
Yes, but with caution. Beta-blockers blunt the heart-rate response to hypoglycaemia, making low blood sugar harder to recognise. Sweating remains a reliable warning sign. Monitor blood glucose carefully when starting.
Why is once-daily not enough?
Most beta-blocker drops have an 8–12 hour duration of action, so twice-daily dosing maintains 24-hour IOP control. Some gel-forming preparations (timolol XE) extend duration and are dosed once daily.
What happens if I stop suddenly?
IOP returns to baseline within 1–2 weeks. There is no ophthalmic withdrawal syndrome. However, if you take oral beta-blockers as well, do not stop those abruptly without cardiology advice.
Can I wear contact lenses?
Remove lenses before instillation (preservative is benzalkonium chloride which can be absorbed by soft lenses) and wait 15 minutes before reinserting.
What is corneal anaesthesia?
Some beta-blockers cause mild reduction in corneal sensation. This is rare but can mask the discomfort of corneal abrasions or foreign bodies. Report any unusual eye pain promptly.
Can I use Iotim Eye Drops alongside oral medications for blood pressure?
Most combinations are safe but disclose all medications to your prescriber. ACE inhibitors, ARBs, and amlodipine are usually compatible. Avoid combining with oral beta-blockers without medical advice.
Other Eye-Care Medications
Customers viewing this product also consider these alternatives in our Eye Care range:
- Xalatan Eye Drop (latanoprost)
- Azopt Eye Drops (brinzolamide)
- Alphagan P Drop (brimonidine)
- Iotim Eye Drops (timolol)
- Careprost (bimatoprost)
Medical Disclaimer
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Strength | 0.5% w/v 5ml |
|---|---|
| Quantity | 1 Bottle/s, 2 Bottle/s, 3 Bottle/s, 6 Bottle/s |
Iotim Eye Drops
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