💡 Quick Answer — What is Thrombophob Gel?
Thrombophob Gel contains heparin sodium 200 IU/g + benzyl nicotinate 2% — a topical anticoagulant + vasodilator combination for superficial thrombophlebitis (inflamed superficial veins), bruises, haematomas, sports-injury soft-tissue swelling. Apply a thin layer 2–3 times daily over the affected area; massage gently. Do not apply to broken skin or open wounds. Topical heparin has minimal systemic anticoagulant effect — safe to use alongside oral anticoagulants. Benzyl nicotinate is a vasodilator that increases local circulation and improves heparin penetration.
📦 Κάθε παραγγελία καλύπτεται από την Πολιτική Εγγύησης Επαναποστολής — εάν το δέμα σας δεν φτάσει εντός 20 εργάσιμων ημερών, το επαναποστέλλουμε.
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Τα γενόσημα φάρμακά μας προέρχονται από κατασκευαστές που πιστοποιούνται από την WHO-GMP και αποστέλλονται παγκοσμίως σε διακριτική, απλή συσκευασία — χωρίς όνομα φαρμάκου στο εξωτερικό του δέματος. Οι πληρωμές με κάρτα δρομολογούνται μέσω ρυθμισμένου επεξεργαστή (οι περιγραφές εκκαθάρισης περιλαμβάνουν ρυθμισμένο επεξεργαστή πληρωμών με κάρτα — ποτέ “MedsBase” ή οποιοδήποτε όνομα φαρμάκου). Γίνονται δεκτές και πληρωμές με κρυπτονομίσματα και τραπεζική μεταφορά SEPA. Κάθε παραγγελία καλύπτεται από την Πολιτική Επαναποστολής Εξασφαλίσεώς μας.
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Choosing Thrombophob Gel from MedsBase:
- WHO-GMP certified manufacturer — sourced from a regulated facility, finished pack with batch number and expiry.
- Διακριτική συσκευασία — plain envelope, no medication name on the outside.
- Παγκόσμια αποστολή with Reshipment Assurance — if your parcel does not arrive within 20 business days we re-ship at no cost (subject to policy terms).
- Loyalty points — 1 point per $1 spent (excludes peptides); 100 points = $5 off.
What Thrombophob Gel is and how it works
Thrombophob Gel contains heparin sodium 200 IU/g + benzyl nicotinate 2%. Heparin is a natural anticoagulant glycosaminoglycan; topically, it is absorbed by superficial vessels and dissolves the small clots in superficial veins (thrombophlebitis), bruises, and haematomas. Benzyl nicotinate is a peripheral vasodilator (a niacin ester) that produces transient skin warmth, redness, and increased local blood flow — accelerating clot resolution and improving heparin tissue penetration. Manufacturer: Panacea Biotec (WHO-GMP certified).
Indications
- Superficial thrombophlebitis — painful, red, hard cord along a superficial vein (often after IV cannulation).
- Bruises and haematomas — speeds resorption, reduces pain.
- Soft-tissue trauma and sports injury — sprains, contusions.
- Post-cannulation phlebitis — painful, inflamed insertion sites.
- Varicose-vein-related discomfort — adjunct, not a substitute for compression or vein procedure.
How to apply
- Wash hands. Apply a thin layer 2–3 times daily over the affected area.
- Gently massage in until absorbed.
- Do not apply to broken skin, open wounds, mucous membranes, or eyes.
- Initial transient warmth and redness from benzyl nicotinate is normal — usually settles in 30 minutes.
- Continue for 5–14 days depending on severity; reassess at 7 days.
⚠️ When to seek medical advice — Topical heparin treats superficial thrombophlebitis. It does NOT treat deep vein thrombosis (DVT). A red, swollen, painful, warm calf or thigh with leg swelling needs urgent assessment for DVT (Doppler ultrasound) — DVT requires systemic anticoagulation, not topical therapy. Equally, sudden chest pain or breathlessness (suspected pulmonary embolism) is a medical emergency. Thrombophob Gel is for superficial vein and soft-tissue use only.
Side effects
- Common: transient skin warmth, mild redness from benzyl nicotinate (usually settles in 30 minutes).
- Less common: mild itching, contact dermatitis, irritation at application site.
- Rare: heparin-induced skin necrosis at application site (with very prolonged extensive use), severe allergic reaction.
Contraindications
- Hypersensitivity to heparin, niacin esters, or formulation excipients.
- Open wounds, broken skin, mucous membranes, eyes.
- Heparin-induced thrombocytopenia (HIT) history — relative contraindication.
- Severe atopic dermatitis at the application site.
Drug interactions
Topical heparin has minimal systemic absorption — does not significantly interact with oral anticoagulants (warfarin, DOACs) or affect INR. Patients on systemic anticoagulants can use Thrombophob Gel safely.
Pregnancy & breastfeeding
Topical heparin has minimal systemic absorption; considered safe in pregnancy and breastfeeding for short courses on small areas. Avoid breast/nipple application.
Storage
Store below 25 °C in the original tube. Keep tube tightly closed.
Συχνές Ερωτήσεις
How is topical heparin different from injectable heparin?
Topical heparin treats superficial conditions (phlebitis, bruises) with negligible systemic anticoagulant effect. Injectable heparin (subcutaneous or IV) treats DVT, PE, and other systemic thromboembolism — and requires monitoring (anti-Xa, aPTT).
How long until I see results?
Reduction in pain and redness within 2–4 days; full resolution in 1–2 weeks.
Is Thrombophob Gel safe with warfarin/DOACs?
Yes — topical heparin has no clinically significant systemic effect and does not affect INR or DOAC efficacy.
Why does my skin go red after applying?
The benzyl nicotinate component is a vasodilator that causes transient skin redness and warmth. This usually resolves within 30 minutes and reflects expected drug action.
Can I use Thrombophob Gel for varicose veins?
It can relieve discomfort but does not treat the underlying venous insufficiency. Compression stockings, elevation, and venous procedures (sclerotherapy, endovenous laser, surgery) are definitive treatments.
How do I know if it is DVT and not superficial phlebitis?
Superficial thrombophlebitis is a tender red cord along a visible vein (calf or arm); DVT is a deep, swollen, painful leg without a visible vein. DVT requires urgent Doppler ultrasound and systemic anticoagulation. If unsure, seek medical advice.
Is it safe in pregnancy?
Yes — topical heparin is considered safe in pregnancy due to minimal systemic absorption.
Can I cover the area with a bandage?
A light non-compressive dressing is acceptable for cosmetic reasons. Avoid tight compression — it does not enhance the topical effect and can cause skin irritation.
How long can I use Thrombophob Gel?
5–14 days for most indications. If symptoms persist beyond 2 weeks, reassess for underlying chronic venous disease or other condition.
Can I use Thrombophob Gel for haemorrhoids?
No — there are dedicated anorectal preparations. Thrombophob Gel is formulated for limb application and contains a vasodilator that may be irritating to anorectal mucosa.
Where topical Thrombophob Gel only soothes superficial varicose veins, definitive closure is achieved by injecting a sclerosant such as Setrol Injection (sodium tetradecyl sulfate 1% / 3%), administered into the affected vein by a trained clinician.
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Medical disclaimer. This content is for general information about the product and is not medical advice or a substitute for advice from a qualified healthcare professional. Use any topical or oral medication only under appropriate medical supervision; misuse can cause serious harm.






























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