Opiprol

✅ Anxiety relief
✅ Depression management
✅ Mood stabilization
✅ Improved sleep quality
✅ Minimal side effects

Opiprol contains Opipramol.

Tuotekoodi: Ei saatavilla Kategoria: Kategorian yleiskatsaus, Krooniset sairaudet, Tilannehermostuksen hoito Avainsana: Opipramol, Opiprol

✓ Lääketieteellinen tarkistus Morgan Ellis — Farmasian tutkija · 8 vuoden kokemus · Viimeisin arvio: toukokuu 2026

Osta enemmän, säästä enemmän Hinta per tabletti

30 tablettia

US$1.40/tabletti

42,00 $

60 tablettia

US$1.25/tabletti · säästä 11%

US$75.00

90 tablettia

US$1.11/tabletti · säästä 21 %

US$100.00

180 tablettia PARAS ARVO

US$0.91/tabletti · säästä 35%

US$163.00

Salattu kassavaihe

Kryptomaksut 10% halvempia

Hienovaraiset maailmanlaajuiset toimitukset

1 400+ asiakasta · 50+ maata

Vahvuus

100 mg

Määrä

30 tablettia
60 tablettia
90 tablettia
180 tablettia

Tyhjennä

⚡ Quick Answer — What is Opiprol?

Opiprol sisältää opipramol 50 mg from a WHO-GMP certified manufacturer (Sun Pharma) — an atypical TCA-related anxiolytic with primary use in generalised anxiety disorder (GAD) and somatoform disorders. Distinct from classic TCAs: opipramol does ei inhibit monoamine reuptake. Its mechanism is dominated by sigma-1 and sigma-2 receptor agonism plus H₁ antihistamine and weak D2 antagonism. Standard dose: 50–150 mg/day in 1–3 divided doses. Onset: 1–3 weeks. Marketed primarily in Germany, Switzerland, Austria, and parts of Eastern Europe as Insidon. Not FDA-approved — not available in the US or UK as a licensed product. Lower anticholinergic burden than classic TCAs.

Mitä saat MedsBasen kautta: WHO-GMP sertifioitu valmistaja · Hienotunteinen pakkaus · Maailmanlaajuinen toimitus · 1 400+ varmennettua asiakasarviota

📦 Jokainen tilaus on katettuna meidän Reshipment Assurance Policy -politiikkamme piiriin — jos lähetyksesi ei saavu 20 arkipäivässä, lähetämme uuden.

Miksi tilata MedsBasesta

Geneeriset lääkkeemme on hankittu WHO-GMP sertifioiduilta valmistajilta ja toimitettu maailmanlaajuisesti hienotunteisessa, neutraalissa pakkauksessa — lääkkeen nimeä ei ole pakkauksen ulkopuolella. Korttimaksut käsitellään säädeltyjen maksunvälittäjien kautta (tilisiirtojen kuvaukset sisältävät säädellyn korttimaksun käsittelijän — ei koskaan “MedsBase” tai lääkkeen nimeä). Kryptovaluutat ja SEPA-pankkisiirrot hyväksytään myös. Jokainen tilaus on turvattu meidän Reshipment Assurance Policy -takuuohjelmalla.

Important — this is not a situational-anxiety medication. Opiprol is a tricyclic-related anxiolytic (sigma-receptor agonist), prescribed and titrated over weeks for generalised anxiety disorder (GAD), somatoform disorders, and adjunctive depression in countries where it is approved. It is ei the right drug for acute, performance-related anxiety (flying, public speaking, exams) — for those use cases beta-blockers (propranolol), benzodiazepines, or hydroxyzine are clinically appropriate. If you do not have a diagnosed mood, anxiety, or psychiatric disorder, do not start this medication.

FDA black-box warning — suicidality. All antidepressants carry an FDA black-box warning for increased risk of suicidal thinking and behaviour in children, adolescents, and young adults under 25, particularly during the first weeks of treatment or after dose changes. Family members and prescribers should monitor closely for worsening mood, agitation, or suicidal ideation in this age group.

What Is Opiprol?

Opiprol is an oral tablet of opipramol dihydrochloride 50 mg manufactured by Sun Pharma. Opipramol is a tricyclic compound structurally related to imipramine but pharmacologically very different — it does not significantly inhibit serotonin or norepinephrine reuptake. Instead it is a high-affinity sigma-1 and sigma-2 receptor agonist with secondary H₁-antihistamine and weak D2-antagonist action. It has been used clinically since 1961 (introduced as Insidon by Geigy) and remains a standard outpatient anxiolytic in the German-speaking world.

Hyväksytyt käyttöaiheet

Generalised anxiety disorder (GAD) — the primary clinical use
Somatoform disorders — somatisation, persistent functional somatic symptoms
Adjunctive treatment in mild-to-moderate depression with prominent anxiety
Insomnia secondary to anxiety

Annostus

Käyttöaihe	Start	Typical	Enimmäismäärä	Huomautuksia
GAD, somatoform	50 mg evening × 3–5 days	50–150 mg/day in 1–3 doses	300 mg/day	Most prescribers use 50–100 mg evenings or 50 mg + 100 mg morning + evening
Anxiety with insomnia	50 mg at bedtime	50–100 mg at bedtime	150 mg at bedtime	Sedation peaks 2–3 h after dose
Elderly	25–50 mg evening	50–100 mg/day	150 mg/day	Lower target; more sensitive to sedation and orthostasis

Haittavaikutukset

Side-effect profile

Taajuus	Vaikutus	Huomautuksia
Yleinen	Sedation, fatigue	Useful at bedtime; can be limiting if dosed during the day
Yleinen	Kuivaa suuta	Mild anticholinergic burden — less than imipramine or amitriptyline
Yleinen	Weight gain (modest)	H₁ appetite stimulation
Yleinen	Dizziness, mild orthostatic hypotension	Caution standing quickly, particularly in elderly
Less common	Constipation, blurred vision	Anticholinergic
Harvinainen	QT prolongation	Caution with other QT-prolonging drugs
Harvinainen	Hyponatraemia, transient liver enzyme elevation	Monitor in long-term use

Lääkeaineenvaihdunta

Avoid combination with MAOIs — 14-day washout though serotonin syndrome risk is low given absent SERT activity.

Additive CNS depression: alcohol, benzodiazepines, opioids, antihistamines — combine cautiously.

QT prolongation: caution with citalopram (high dose), fluoroquinolones, quetiapine, ondansetron.

Anticholinergic burden: additive with diphenhydramine, oxybutynin, trihexyphenidyl.

Usein Kysytyt Kysymykset

How long does Opiprol take to work?

Some patients notice improvement in anxiety and sleep within 1–2 weeks; full GAD response typically appears at 4–6 weeks of consistent dosing.

Is Opiprol a true antidepressant?

It is structurally a tricyclic but pharmacologically more an anxiolytic. Its primary licensed use across Europe is GAD and somatoform disorders, not classic depression. SSRIs and SNRIs are first-line where MDD is the dominant problem.

Why is Opiprol not used in the US or UK?

Opipramol was developed in Switzerland in 1961 and never pursued by manufacturers for FDA / MHRA approval. It remains a standard prescription drug in Germany, Switzerland, Austria, Poland, Turkey, and other European markets.

Is Opiprol safer than benzodiazepines for chronic anxiety?

Yes — opipramol has no dependence potential, no abuse risk, and no rebound anxiety on stopping. It is a sensible alternative when benzodiazepines would be problematic for chronic GAD.

Will Opiprol cause dependence or withdrawal?

No physiological dependence is recognised. Mild rebound insomnia or anxiety can occur if a long-term dose is stopped abruptly — tapering over 1–2 weeks is sensible.

Can I drink alcohol on Opiprol?

Avoid heavy alcohol — additive sedation. Light occasional alcohol is generally tolerated.

Is Opiprol safe in pregnancy?

Limited safety data — not preferred in pregnancy. Discuss alternatives with the prescriber.

What happens if I miss a dose?

Take it as soon as you remember unless close to the next dose. Missing a single dose rarely causes problems given the long half-life.

Will Opiprol cause sexual side effects?

Less than SSRIs — opipramol is often used as a switch destination when SSRI-induced sexual dysfunction is intolerable in patients whose primary problem is anxiety rather than depression.

How should Opiprol be stored?

Store at 15–30 °C in the original blister packaging, away from moisture and sunlight. Keep out of reach of children.

Medical disclaimer: Information on this page is intended for adults using prescribed psychiatric medication and is not a substitute for individualised medical care. Antidepressants, antipsychotics, and related medications can interact with other drugs, alcohol, and pre-existing conditions. Discuss any new medication, dose change, or planned discontinuation with a qualified prescriber. If you experience suicidal thoughts, mania, severe akathisia, signs of serotonin syndrome (high fever, confusion, muscle rigidity, rapid heart rate), or neuroleptic malignant syndrome, seek emergency care immediately.