Estocin Ointment
Estocin (erythromycin 0.5% eye ointment) — macrolide for bacterial conjunctivitis and standard neonatal ophthalmia neonatorum prophylaxis at birth. Soothing oily base.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Estocin Ointment?
Estocin Ointment is Erythromycin 0.5% ophthalmic ointment, a macrolide antibiotic for bacterial conjunctivitis, blepharitis, and Chlamydia trachomatis (trachoma). Used twice daily for 1–7 days depending on indication. Safe in pregnancy and infants.
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What is Estocin Ointment?
Estocin Ointment is manufactured by Estee Pharmaceuticals and contains Erythromycin 0.5% as a sterile ophthalmic ointment. Macrolides are bacteriostatic antibiotics with strong activity against Gram-positive cocci, atypical organisms (Chlamydia, Mycoplasma), and some Gram-negative coverage.
How It Works
Erythromycin binds the 50S bacterial ribosomal subunit, blocking peptidyl transferase activity and preventing protein synthesis. The result is bacteriostatic at lower concentrations and bactericidal at higher doses against susceptible organisms. Topical Erythromycin achieves high local concentrations in the conjunctiva and tear film.
Indications
- Bacterial conjunctivitis (Staphylococcus, Streptococcus, Moraxella, Haemophilus)
- Bacterial blepharitis — particularly Staphylococcus aureus
- Neonatal ophthalmia prophylaxis — applied at birth to prevent gonococcal and chlamydial conjunctivitis (standard of care globally)
- Meibomian gland dysfunction — small ribbon to lid margin as part of blepharitis management
Dosing
| Indication | Dose |
|---|---|
| Bacterial conjunctivitis (ointment) | Apply a small ribbon (~0.5 cm) to affected eye(s) up to 6 times daily for 5–7 days |
| Neonatal prophylaxis | Single 1 cm ribbon to each eye within 1 hour of birth |
Side Effects
Local: mild stinging on instillation, transient blurred vision (especially with ointment), eye irritation, foreign body sensation, conjunctival hyperaemia, ocular itching.
Systemic: negligible from topical use.
Warnings & Contraindications
- Hypersensitivity to macrolides (azithromycin, erythromycin, clarithromycin)
- Viral or fungal keratitis
- Pregnancy — Category B; generally safe topically
- Breastfeeding — compatible
- Children — safe from infancy (erythromycin ointment is the preferred neonatal prophylaxis)
Storage
Store at 8–25°C. Discard 28 days after first opening.
Frequently Asked Questions
When is Estocin Ointment used?
Bacterial conjunctivitis, blepharitis, neonatal ophthalmia prophylaxis, meibomian gland dysfunction. Particularly useful in pregnancy and infancy because of the favourable safety profile.
How does Estocin Ointment differ from fluoroquinolones?
Erythromycin is bacteriostatic at typical doses; fluoroquinolones are bactericidal. Erythromycin has stronger activity against atypical organisms (Chlamydia) and is preferred in pregnancy and neonates. Fluoroquinolones have stronger Pseudomonas coverage.
Is Estocin Ointment safe in pregnancy?
Yes — Category B, generally considered safe. Topical absorption is minimal.
Why is Estocin Ointment sometimes given just for 3 days in trachoma?
Azithromycin’s long tissue half-life means a 3-day course delivers therapeutic concentrations in conjunctival tissue for 5–7 days. WHO-endorsed mass treatment programmes use this short course quarterly for trachoma elimination.
Can Estocin Ointment be used in newborns?
Yes — erythromycin ophthalmic ointment is the WHO-endorsed neonatal prophylaxis applied at birth to prevent gonococcal and chlamydial conjunctivitis.
What if my eyes are still red after treatment?
Bacterial conjunctivitis usually clears within 5–7 days. Persistent redness suggests a different diagnosis: allergic conjunctivitis, viral keratoconjunctivitis, dry-eye disease, or a missed differential like episcleritis. Re-evaluate.
Will Estocin Ointment blur my vision?
Yes — ointments cause 5–10 minutes of blur after each application. Use at bedtime when possible.
Can I wear contact lenses?
Stop lenses during treatment and for 24 hours after symptoms resolve.
What if I get a hypersensitivity reaction?
Stop the drop. Switch to a non-macrolide antibiotic class. True hypersensitivity is rare with topical macrolides.
How is Estocin Ointment stored?
Room temperature 15–25°C, or refrigerator if labelled, protected from light. Discard after 28 days.
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Medical Disclaimer
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Strength | 1% |
|---|---|
| Quantity | 1 Ointment/s, 3 Ointment/s, 6 Ointment/s |
| Pharma Form | Eye Drop/s |
| Manufacturer | Sunways India |
| Treatment | Bacterial eye infection |
| Generic Brand | Erythromycin |
Estocin Ointment
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Estocin Ointment
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