Asthafen
✅ Allergy symptom relief
✅ Non-drowsy formula
✅ Rapid symptom control
✅ Enhanced comfort
Contains Ketotifen Fumarate
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Asthafen?
Asthafen bevat ketotifen — an oral mast-cell stabiliser and H1 antihistamine. Used as a long-term preventer for allergic asthma (especially in children), atopic dermatitis flares, and chronic allergic rhinitis. Onset of preventer benefit takes 4–8 weeks of consistent twice-daily dosing. Modern asthma guidelines have largely moved away from ketotifen in favour of inhaled corticosteroids (ICS), but it remains useful in young children and in atopic patients with multiple allergic comorbidities. Manufactured by Cipla; international brand Zaditen.
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What Is Asthafen?
Asthafen contains ketotifen 1 mg per tablet (also available as 1 mg/5 ml syrup). Ketotifen has dual action: it stabilises mast-cell membranes (preventing IgE-driven degranulation and histamine release) and blocks H1 receptors. Internationally sold as Zaditen.
How Does Ketotifen Work?
- Mast-cell membrane stabilisation — prevents IgE-mediated release of histamine, leukotrienes, and tryptase.
- H1 receptor antagonism — blocks histamine-mediated itch, sneeze, runny nose, and (mild) bronchoconstriction.
- Reduces airway hyperreactivity over 4–8 weeks of consistent dosing.
Toepassingen en Indicaties
- Allergic asthma in children — preventer adjunct (especially when ICS adherence is poor)
- Allergic rhinitis — chronic perennial form
- Atopic dermatitis — adjunct
- Chronic urticaria — alternative to second-generation antihistamine
- Allergische conjunctivitis
Asthafen Dosage
| Patiënt | Dosering | Frequentie |
|---|---|---|
| Adults & children >3 yr | 1 mg | Twice daily with food |
| Children 6 mo – 3 yr | 0.5 mg | Twice daily with food |
| Sedation-prone patients | Start at 0.5 mg evening dose | Titrate up over 1 week |
Side Effects of Asthafen
- Drowsiness (commonest — usually settles within 1–2 weeks)
- Mild weight gain (appetite stimulation)
- Droge mond
- Duizeligheid
- Hoofdpijn
Ernstig — stop en zoek hulp:
- Ernstige allergische reactie
- Severe drowsiness preventing daily function
- Mood change, agitation in children
Waarschuwingen en voorzorgsmaatregelen
- Drowsiness: avoid driving or operating machinery until you know how it affects you.
- Not a rescue medication. Use SABA (Asthalin, Levolin) for acute bronchospasm.
- Continue ICS if previously prescribed; ketotifen does not replace inhaled corticosteroids.
- Slow onset: 4–8 weeks of consistent dosing required for full effect.
- Zwangerschap en borstvoeding: use only when benefits outweigh risks; second-generation antihistamines (loratadine, levocetirizine) preferred.
Contra-indicaties
- Hypersensitivity to ketotifen
- Concomitant oral antidiabetics (rare reports of reversible thrombocytopenia in combination)
Geneesmiddelinteracties
- Sedatives, alcohol, hypnotics — additive sedation
- Oral antidiabetics — reversible thrombocytopenia (rare)
- CNS depressants — additive sedation
Opslag
- Bewaren beneden 25°C in a cool, dry place away from direct sunlight.
- Keep in original packaging until use to protect from moisture and light.
- Do not use after the expiry date printed on the strip.
- Buiten bereik van kinderen houden.
Gerelateerde alternatieven op MedsBase
- Asthalin Inhaler — salbutamol verlichter
- Budecort Inhaler — budesonide ICS-preventer
- Foracort Inhaler — budesonide + formoterol ICS-LABA
- Montair — montelukast LTRA-tablet
- Tiova Inhaler — tiotropium LAMA voor COPD
Veelgestelde vragen
How is ketotifen different from cetirizine or loratadine?
Ketotifen has dual action (mast-cell stabilisation + H1 block) and longer-term preventer effect on allergic disease. Modern second-generation antihistamines (loratadine, cetirizine, levocetirizine) are non-sedating but lack the mast-cell stabilisation. For acute allergy: a non-sedating antihistamine. For chronic preventer effect in allergic asthma/rhinitis: ketotifen.
Why is ketotifen still used in children?
It is well-tolerated, available as a syrup, and the mild sedation can be helpful with bedtime dosing in atopic children with sleep disturbance from itch.
Will Asthafen replace my inhaler?
No — it is an add-on preventer, not a replacement for ICS or reliever therapy.
Hoelang duurt het voordat ik verbetering merk?
4–8 weeks for full preventer effect on asthma and rhinitis. Antihistamine effect (itch, sneeze) starts within hours.
Is Asthafen safe in pregnancy?
Limited data; generally avoided in favour of better-studied second-generation antihistamines.
Can I drink alcohol on Asthafen?
Alcohol amplifies the drowsiness — avoid or minimise.
How long can children take Asthafen?
Indefinite use is acceptable while symptoms persist; reassess every 6–12 months.
Why must I take it with food?
Reduces stomach upset; bioavailability is unaffected.
Can I stop Asthafen suddenly?
No taper needed for ketotifen specifically, but allergic symptoms will return — discuss long-term plan with your prescriber.
Gerelateerde alternatieven
Andere producten in Chronische aandoeningen die klanten ook bekijken:
Meer opties in Astma/COPD-behandeling
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 1 mg |
|---|---|
| Hoeveelheid | 30 Tablet/s, 60 Tablet/s, 90 Tablet/s |
| Farmaceutische vorm | Tablet/s |
| Fabrikant | Torrent Pharma |
| Behandeling | Astma |
| Generiek merk | Salbutamol |
Asthafen
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Asthafen
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