Chlamydia trachomatis is the most common bacterial sexually transmitted infection globally. Many infections are asymptomatic — making screening important — but untreated infection causes pelvic inflammatory disease, ectopic pregnancy, and tubal infertility in women, and epididymo-orchitis and reactive arthritis in men. The MedsBase Chlamydia Treatment catalogue stocks the standard antibiotic regimens, supplied by WHO-GMP gecertificeerde fabrikanten.
Azithromycin — first-line single-dose option. Azithromycin 1 g single oral dose remains the most-used regimen worldwide for uncomplicated genital chlamydia. Single-dose convenience improves compliance compared to 7-day courses. Stocked as Asitomycin 500 (two tablets), Azilup, en Azeetop. Note: 2018 Geisler trial showed slightly lower cure rates than doxycycline for rectal chlamydia (~85% vs ~99%), and BASHH 2015 / CDC 2021 now recommend doxycycline as first-line for genital, rectal, and oropharyngeal infections in non-pregnant adults.
Doxycycline — modern preferred regimen. Doxycycline 100 mg twice daily for 7 days is the modern first-line for non-pregnant adults — higher cure rates for rectal and pharyngeal sites and important for LGV serovar treatment. Doxycycline is catalogued in our Antibiotica category. Avoid in pregnancy.
Cefixime — for gonorrhoea coverage / empiric STI treatment. Many patients treated empirically for chlamydia are also at risk for gonorrhoea — cefixime 800 mg single oral dose covers most gonorrhoeae strains and may be combined with azithromycin or doxycycline for empiric dual treatment. Stocked as Neckcin 100 DT en Neckcin 250 DT. CDC 2021 prefers IM ceftriaxone for confirmed gonorrhoea — cefixime is for resource-limited or oral-preference contexts.
Combinatiepakketten. The SOA-beschermingspakket (azithromycin + secnidazole + fluconazole) provides broad-spectrum coverage for situations where lab testing is delayed or unavailable. The Medische noodkit is a broader acute-care bundle.
Hoe te gebruiken. Confirmed chlamydia → doxycycline 100 mg BID × 7 days (preferred) or azithromycin 1 g single dose (alternative). Pregnancy → azithromycin 1 g single dose (doxycycline contraindicated). Rectal chlamydia → doxycycline 100 mg BID × 7 days mandatory (azithromycin substantially less effective). LGV → doxycycline 100 mg BID × 21 days. Test of cure recommended at 4 weeks for pregnancy / persistent symptoms / suspected reinfection.
Belangrijk. Ideally, confirm chlamydia by NAAT (nucleic acid amplification test) before treating — empiric treatment without testing misses co-infections (gonorrhoea, syphilis, HIV) and treats wrong-cause urethritis with no benefit. Notify recent sexual partners (last 6 months for symptomatic patients, last 60 days for asymptomatic) so they can be tested and treated. No sex (or condom-only) for 7 days after single-dose treatment or until 7-day doxycycline course completed AND partners treated. Repeat NAAT testing at 3 months is recommended even after successful treatment because of high reinfection rates. Symptoms of pelvic inflammatory disease (lower abdominal pain, fever, deep dyspareunia, abnormal bleeding) need same-day medical assessment.
All MedsBase Chlamydia Treatment products ship from WHO-GMP gecertificeerde fabrikanten met discrete verpakking en vallen onder onze Reshipment Assurance Policy.