Ciplox-D Eye Drops
Ciplox-D (ciprofloxacin 0.3% + dexamethasone 0.1%) — fluoroquinolone + steroid eye drop. Bacterial conjunctivitis with marked inflammation. Avoid in viral or fungal keratitis.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Ciplox-D Eye Drops?
Ciplox-D Eye Drops combines Ciprofloxacin HCl 0.3% (a 2nd-generation fluoroquinolone antibiotic) with Dexamethasone 0.1% (a corticosteroid) for bacterial eye infection complicated by significant inflammation. Used after cataract surgery, in bacterial blepharoconjunctivitis with marked redness, and selected post-operative regimens. Avoid in viral, fungal, or amoebic keratitis.
📦 Elke bestelling is gedekt door onze Reshipment Assurance Policy — als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.
Waarom bestellen bij MedsBase
Ciplox-D Eye Drops is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy — als het niet is aangekomen na 20 werkdagen, sturen wij het opnieuw zonder extra kosten. Ondersteund door meer dan 1.400 geverifieerde klantbeoordelingen.
What is Ciplox-D Eye Drops?
Ciplox-D Eye Drops is manufactured by Cipla — a sterile fixed combination of Ciprofloxacin HCl 0.3% and Dexamethasone 0.1% in a single ophthalmic solution. The dual mechanism kills susceptible bacterial pathogens while suppressing the inflammatory response that contributes to redness, swelling, and discomfort. Reserved for situations where both bacterial infection and clinically significant inflammation are confirmed.
Hoe het werkt
Ciprofloxacin HCl inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, the enzymes that supercoil and uncoil bacterial DNA during replication and repair. Without functional enzymes, the bacterial chromosome fragments and the cell dies. Ciprofloxacin remains highly active against Pseudomonas aeruginosa and most Gram-negative ocular pathogens. Dexamethasone binds intracellular glucocorticoid receptors and suppresses transcription of pro-inflammatory cytokines, reducing leukocyte trafficking, capillary permeability, and tissue oedema.
Indicaties
- Bacterial conjunctivitis with significant inflammation — mucopurulent discharge plus marked redness/oedema
- Bacterial blepharoconjunctivitis
- Post-cataract surgery — antibiotic prophylaxis bundled with steroid for inflammation control
- Post-corneal-transplant regimens — under specialist supervision
- Bacterial keratitis with corneal oedema — specialist setting only; combination only after culture/diagnosis
Dosering
| Indicatie | Dosering |
|---|---|
| Bacterial conjunctivitis with inflammation | 1–2 drops every 4 hours while awake for 7–10 days |
| Severe inflammation (first 24–48 h) | 1–2 drops every 2 hours, then taper |
| Post-cataract surgery | 1 drop QID for 7 days, then taper over 2–4 weeks per surgeon |
| Bacterial keratitis (specialist) | As directed; intensive frequency may be needed |
Tapering is essential — abrupt steroid withdrawal can cause inflammatory rebound. Course length is set by the prescribing ophthalmologist; typical total exposure is 7–14 days, with longer regimens reserved for surgical recovery and reviewed regularly.
Bijwerkingen
Steroid-related: elevated intraocular pressure (steroid response — typically appears 2+ weeks into therapy; about 30% of the population are ‘steroid responders’), posterior subcapsular cataract with prolonged use, delayed corneal/conjunctival wound healing, secondary infection from immune suppression (especially fungal and herpetic).
Antibiotic-related: stinging or burning on instillation (most common), conjunctival hyperaemia, lid margin crusting, foreign body sensation, photophobia, white crystalline corneal precipitate (a recognised ciprofloxacin signature — settles on stopping).
Allergic reactions: rare but reported. Discontinue if rash, severe itching, or lid swelling develops.
Waarschuwingen & Contra-indicaties
- Herpes simplex keratitis (dendritic / geographic ulcer) — absolute
- Fungal keratitis — absolute
- Varicella, vaccinia, mycobacterial, or amoebic eye disease — absolute
- Hypersensitivity to fluoroquinolones or to the corticosteroid
- Children — only with specialist supervision and IOP monitoring
- Pregnancy / breastfeeding — discuss with prescriber; topical absorption minimal but steroid Category C
- Open-angle glaucoma — relative contraindication; monitor IOP closely
- Prolonged use beyond 14 days — escalates all risks above
- Contact-lens wear — stop lenses for the duration of treatment
Opslag
Store at 15–25°C protected from light. Shake before each use if the suspension formulation. Do not touch the dropper tip to your eye, lid, or any surface. Discard 28 days after first opening.
Veelgestelde vragen
When is Ciplox-D Eye Drops the right choice?
Bacterial eye infection where inflammation is contributing significantly to symptoms — classically post-cataract surgery, post-corneal-transplant regimens, or significantly inflamed bacterial conjunctivitis confirmed by your prescriber. If unsure whether the infection is bacterial, antibiotic monotherapy is safer.
Why not always combine an antibiotic with a steroid?
Steroids mask infection signs and accelerate viral and fungal corneal disease. Adding steroid to a missed herpes simplex ulcer or fungal keratitis can blind the eye within days. Always confirm bacterial diagnosis first.
What is steroid response?
About 30% of the population have a genetic predisposition to develop elevated intraocular pressure when exposed to topical steroids. Onset is typically 2+ weeks into therapy. Your ophthalmologist should check IOP if you use topical steroid for more than 2 weeks.
How long can I use Ciplox-D Eye Drops?
Most courses are 7–14 days. Post-cataract surgery regimens may extend to 4 weeks with tapering. Indefinite use risks cataract, glaucoma, and opportunistic infection. Always have a defined end-point with ophthalmology review.
What if my vision worsens during treatment?
Stop and seek same-day ophthalmology review. Worsening on antibiotic+steroid is a red flag for missed herpetic, fungal, or amoebic keratitis.
Is Ciplox-D Eye Drops safe in pregnancy?
Topical absorption is minimal, but the steroid component carries Category C status. Discuss with your prescriber; usually possible with short courses when clearly indicated.
Can children use Ciplox-D Eye Drops?
Only under specialist supervision with IOP monitoring. Children are particularly vulnerable to steroid-induced cataract and glaucoma.
What is the white precipitate I see in the eye?
A recognised ciprofloxacin signature — the drug crystallises on the corneal surface in some patients. It is harmless and resolves once treatment ends. If it accumulates significantly, your ophthalmologist may switch you to a different fluoroquinolone.
What if I'm a contact-lens user?
Stop lenses during treatment and for at least 24 hours after symptoms resolve. Steroid-mediated immunosuppression makes contact-lens microbial keratitis particularly dangerous.
What if I have a herpes simplex history?
Disclose this clearly to your prescriber. Steroids can reactivate dormant herpes simplex and convert minor flare-ups into vision-threatening keratitis. A different antibiotic-only regimen is safer.
Andere oogzorgmedicijnen
Klanten die dit product bekijken, overwegen ook deze alternatieven in ons Oogzorg assortiment:
- Pred Forte (prednisolone acetate)
- FML Eye Drop (fluorometholone)
- Lotepred Eye Drop (loteprednol)
- Acular LS (ketorolac)
- Megabrom (bromfenac)
Medische Disclaimer
De informatie op deze pagina is alleen voor educatieve doeleinden en is geen vervanging voor medisch advies van een gekwalificeerde oogarts of optometrist. Oogaandoeningen kunnen snel een bedreiging vormen voor het gezichtsvermogen — plotseling verlies van gezichtsvermogen, hevige pijn of trauma is een oogheelkundig spoedgeval. Raadpleeg altijd een oogzorgprofessional voordat u een behandeling start, stopt of wijzigt.
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| Sterkte | 10 ml |
|---|---|
| Hoeveelheid | 1 Fles/s, 2 Flessen/s, 3 Flessen/s, 6 Flessen/s |
Ciplox-D Eye Drops
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