Montel
✅ Allergy relief
✅ Asthma management
✅ Vermindert ontsteking
✅ Controls bronchoconstriction
✅ Prevents wheezing
Montel contains Montelukast Sodium.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Montel?
Montel bevat montelukast, an oral preventer for asthma and allergic rhinitis. Montelukast blocks cysteinyl leukotriene receptors (CysLT1), mediators released by mast cells and eosinophils that drive bronchoconstriction, mucus production, and airway oedema. Used as add-on preventer therapy for asthma, especially exercise-induced and allergy-triggered asthma, and for allergic rhinitis. Each tablet contains 4 / 5 / 10 mg, geproduceerd door Lupin. Taken once daily in the evening.
Important — neuropsychiatric warning: the FDA added a black-box warning in 2020 noting reports of mood changes, sleep disturbance, anxiety, depression, and (rarely) suicidal ideation with montelukast. Discuss any new mood symptoms with your prescriber.
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Waarom bestellen bij MedsBase
Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen — geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor — nooit “MedsBase” of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.
What Is Montel?
Montel is a montelukast (LTRA) preparation manufactured by Lupin at WHO-GMP certified facilities. Internationally montelukast is sold as Singulair (MSD). Available as 4 mg, 5 mg, and 10 mg tablets — strengths chosen by age and indication.
How Does Montel Work?
Cysteinyl leukotrienes (LTC4, LTD4, LTE4) are inflammatory lipid mediators released by mast cells, eosinophils, and basophils when activated by allergen, exercise, cold air, or aspirin. They bind CysLT1 receptors on airway smooth muscle, eosinophils, and bronchial epithelium — driving bronchoconstriction, eosinophil recruitment, airway oedema, and mucus hypersecretion. Montelukast selectively blocks CysLT1, breaking this cascade.
Toepassingen en Indicaties
- Persistent asthma — add-on preventer in patients not controlled by ICS alone (alternative to LABA or LAMA add-on)
- Exercise-induced asthma — particularly effective; taken 2 hours before exercise
- Aspirin-exacerbated respiratory disease (AERD) — leukotrienes are central to this phenotype
- Allergic rhinitis — both seasonal (hay fever) and perennial
- Allergic conjunctivitis adjunct
- Chronic urticaria — montelukast as adjunct to high-dose antihistamine
Montel Dosage
| Patiënt | Dosering | Frequentie |
|---|---|---|
| Adults & children >15 yr | 10 mg | Once daily in the evening |
| Children 6–14 yr | 5 mg chewable | Once daily in the evening |
| Children 2–5 yr | 4 mg chewable / granules | Once daily in the evening |
| Children 6 mo – 2 yr | 4 mg granules | Once daily — specialist supervision |
Side Effects of Montel
- Hoofdpijn
- Mild abdominal pain or nausea
- Sleep disturbance (vivid dreams, insomnia)
- Mood changes — irritability, anxiety, depression (FDA black-box warning, 2020)
- Upper respiratory infection symptoms
- Huiduitslag
Ernstig — stop en zoek hulp:
- Severe allergic reaction / angio-oedema
- Suicidal ideation or severe depression — STOP and seek urgent psychiatric review
- Churg-Strauss syndrome (eosinophilic vasculitis) — rare; suspect in ICS-tapering patients with new vasculitic features (rash, neuropathy, eosinophilia)
- Hepatitis (rare)
Waarschuwingen en voorzorgsmaatregelen
- Black-box warning — neuropsychiatric events. If new mood changes, anxiety, sleep disturbance, agitation, depression, or suicidal thoughts occur, stop Montel and contact your prescriber.
- Not a rescue medication. Do not use in acute asthma attacks — onset is too slow.
- Continue ICS if previously prescribed; montelukast does not replace inhaled corticosteroids.
- Leverfunctiestoornis: use cautiously in moderate-to-severe disease.
- Zwangerschap en borstvoeding: reasonable safety data; use when benefits outweigh risks.
- Kinderen may show increased risk of behavioural changes — counsel parents to monitor mood.
Contra-indicaties
- Hypersensitivity to montelukast or excipients
- Severe hepatic impairment — relative
Geneesmiddelinteracties
| Interagerend geneesmiddel | Effect | Wat te doen |
|---|---|---|
| Phenobarbital, phenytoin, rifampicin | Induce CYP enzymes — reduce montelukast levels | Monitor asthma control |
| Gemfibrozil | Inhibits CYP2C8 — increases montelukast levels | Voorzichtig gebruiken |
| Warfarine | Theoretical INR change reported in case reports | Monitor INR after starting/stopping |
Opslag
- Bewaren beneden 25°C in a cool, dry place away from direct sunlight.
- Keep in original packaging until use to protect from moisture and light.
- Do not use after the expiry date printed on the strip.
- Buiten bereik van kinderen houden.
Gerelateerde alternatieven op MedsBase
- Asthalin Inhaler — salbutamol verlichter
- Budecort Inhaler — budesonide ICS-preventer
- Foracort Inhaler — budesonide + formoterol ICS-LABA
- Tiova Inhaler — tiotropium LAMA voor COPD
- Montair — montelukast LTRA-tablet
Veelgestelde vragen
When should I take montelukast?
Once daily in the evening, with or without food. Evening dosing matches the typical overnight rise in leukotriene mediators and gives best protection against early-morning symptoms.
How long until montelukast works?
Some symptom relief within 24–48 hours. Full effect on asthma exacerbation rate develops over 4–8 weeks.
Should I worry about the FDA black-box warning?
The 2020 FDA black-box warning highlighted reports of mood changes, sleep disturbance, anxiety, depression, and rarely suicidal ideation — particularly in children. The absolute risk is low but real. Watch for any new mood symptoms in yourself or your child; stop the drug and contact your prescriber if they appear.
Can montelukast replace my inhaler?
No — montelukast is an add-on preventer. It does not replace inhaled corticosteroids (Budecort, Beclate, Foracort, Seretide). Continue ICS as prescribed.
Is montelukast a rescue medication?
No — onset is too slow. Use a SABA (Asthalin, Levolin) for acute attacks.
Can children take montelukast?
Yes from 6 months of age in age-appropriate strengths (4 mg granules, 4 mg or 5 mg chewable, 10 mg tablet). Counsel parents to monitor mood and behaviour.
Is montelukast safe in pregnancy?
Reasonable observational data; use when benefits outweigh risks, particularly in patients whose asthma is well-controlled on it.
Does montelukast help allergic rhinitis?
Yes — montelukast is licensed for both asthma and allergic rhinitis. Particularly useful when both coexist (United Airways disease).
Should I stop montelukast if I feel better?
No — continue daily for as long as your prescriber advises. Stopping leads to gradual return of symptoms over days-to-weeks.
Gerelateerde alternatieven
Andere producten in Chronische aandoeningen die klanten ook bekijken:
Meer opties in Astma/COPD-behandeling
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 10 mg |
|---|---|
| Hoeveelheid | 30 Tabletten, 60 Tabletten, 90 Tabletten, 180 Tabletten |
Montel
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