Dorzox T Eye Drop
Dorzox T (dorzolamide 2% + timolol 0.5%) — fixed-combination CAI + beta-blocker eye drop. Twice-daily IOP control for open-angle glaucoma. Sulfa cross-reactivity caution.
✓ Lékařsky ověřeno Morgan Ellis — Pharmacy Researcher · 8 years experience Last reviewed: May 2026
⚡ Quick Answer — What is Dorzox T Eye Drop?
Dorzox T Eye Drop combines dorzolamide 2% (carbonic anhydrase inhibitor) with timolol 0.5% (beta-blocker) in one bottle for advanced glaucoma. Twice-daily dosing. Avoid in asthma, severe COPD, bradycardia, AV block, and severe sulfonamide allergy.
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Dorzox T Eye Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Zárukou opětovného odeslání — if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.
What is Dorzox T Eye Drop?
Dorzox T Eye Drop is a fixed-dose combination eye drop manufactured by Cipla, containing dorzolamide HCl 2% (CAI) and timolol maleate 0.5% (non-selective beta-blocker) in a 5 mL bottle. Both components reduce aqueous humour production through different mechanisms, giving moderately additive ~25–30% IOP reduction in twice-daily dosing.
Jak to funguje
Dorzolamide blocks carbonic anhydrase II in the ciliary epithelium, reducing bicarbonate-driven aqueous secretion. Timolol blocks beta-adrenergic receptors at the same site, reducing cAMP-driven aqueous secretion. The combination is more potent than either monotherapy and equivalent to giving the two drugs separately, with the convenience of a single bottle.
Indications & Dosing
One drop in affected eye(s) twice daily (morning and evening). Wait 5 minutes between other eye drops. Practise punctal occlusion for 1–2 minutes after each drop to reduce systemic timolol absorption. Remove contact lenses before instillation; reinsert after 15 minutes.
Vedlejší účinky
Local: stinging, bitter taste, blurred vision, conjunctival hyperaemia, ocular pruritus, dry eye, eyelid dermatitis.
Systemic (mostly from timolol): bradycardia, hypotension, fatigue, depression, bronchospasm in reactive airways, masking of hypoglycaemia signs, decreased libido.
Warnings & Contraindications
- Asthma, severe COPD — absolute contraindications
- Sinus bradycardia, second/third-degree AV block, decompensated heart failure
- Severe sulfonamide hypersensitivity
- Severe renal impairment (CrCl < 30)
- Concurrent oral beta-blockers, calcium-channel blockers, or digoxin — additive bradycardia
- Pregnancy Category C — avoid
- Corneal endothelial dysfunction
Skladování
Store at 15–25°C protected from light. Discard 28 days after first opening.
Často kladené dotazy
When should I use Dorzox T Eye Drop?
Twice daily, morning and evening, ideally 12 hours apart.
Why a fixed combination?
Adherence improves significantly with one bottle vs two. Both ingredients work on aqueous production from different angles, so the combination is moderately additive (about 1.5× either alone).
Can I use Dorzox T Eye Drop with asthma?
No — the timolol component can trigger bronchospasm even when applied to the eye. Switch to a non-beta-blocker combination or a brinzolamide+brimonidine approach.
What is punctal occlusion?
Pressing the inner corner of your eye for 1–2 minutes after instillation. This blocks the nasolacrimal duct and reduces systemic absorption by ~70%, lowering bradycardia and bronchospasm risk.
Can I drive after instilling Dorzox T Eye Drop?
There is transient blur for 5–10 minutes. Wait until vision clears.
What about kidney stones?
Topical CAIs deliver minimal systemic exposure compared with oral acetazolamide, so kidney-stone risk is very low. If you have a personal or family history of calcium-oxalate stones, mention it to your prescriber.
Will I taste the drop?
A bitter taste is common because of nasolacrimal drainage into the throat. Punctal occlusion minimises this.
What if I have a sulfa allergy?
Severe reactions (Stevens-Johnson, anaphylaxis) to sulfonamides are an absolute contraindication. Mild rash to sulfamethoxazole alone is not — discuss with your prescriber.
Is Dorzox T Eye Drop safe in pregnancy?
Category C. Avoid unless your ophthalmologist determines the benefit outweighs risk. Brimonidine or PGA monotherapy is preferred during pregnancy.
Co když vynechám dávku?
Take it as soon as you remember unless the next dose is close. Never double up.
Other Eye-Care Medications
Customers viewing this product also consider these alternatives in our Péče o oči range:
- Xalatan Eye Drop (latanoprost)
- Azopt Eye Drops (brinzolamide)
- Alphagan P Drop (brimonidine)
- Iotim Eye Drops (timolol)
- Careprost (bimatoprost)
Lékařské upozornění
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Síla | 5 ml Eye Drop |
|---|---|
| Množství | 1 Bottle/s, 3 Bottle/s, 6 Bottle/s |
| Léková forma | Eye Drop/s |
| Výrobce | Cipla Inc |
| Léčba | Péče o oči |
| Generická značka | Dorzolamide + Timolol |
Dorzox T Eye Drop
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