Airz
✅ Allergy symptom relief
✅ Non-drowsy formula
✅ Rapid symptom control
✅ Improved comfort
Contains Glycopyrronium bromide
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Airz?
Airz bevat glycopyrronium bromide, een long-acting muscarinic antagonist (LAMA) bronchodilator that blocks parasympathetic constriction of the airways for 24 hours. Airz is used as once-daily maintenance therapy gedurende chronic obstructive pulmonary disease (COPD) — and (in some markets) as add-on therapy for difficult-to-control asthma. Each rotacaps delivers 50 mcg per rotacap, geproduceerd door Glenmark Pharma at WHO-GMP certified facilities. Same active drug as international brand Seebri Breezhaler. Airz is a controller, not a reliever — keep a SABA (Asthalin, Levolin) for acute breathlessness.
📦 Elke bestelling is gedekt door onze Reshipment Assurance Policy — als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.
Waarom bestellen bij MedsBase
Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen — geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor — nooit “MedsBase” of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.
What Is Airz?
Airz is an Indian-manufactured generic of glycopyrronium bromide, a long-acting anticholinergic bronchodilator. Internationally the same drug is sold as Seebri Breezhaler. glycopyrronium bromide binds muscarinic receptors (M1 and M3) on airway smooth muscle for many hours, providing 24-hour bronchodilation with once-daily dosing. It does not cause the tremor, palpitations, or hypokalaemia of β2 agonists.
How Does Airz Work?
The parasympathetic nervous system maintains a baseline tone in bronchial smooth muscle through acetylcholine acting on M3 muscarinic receptors. In COPD this tone is the dominant reversible component of airflow obstruction. glycopyrronium bromide is a kinetically-selective M3 antagonist — it binds and dissociates slowly, giving sustained bronchodilation over 24 hours. The result is:
- Sustained bronchodilation for 24 hours from a single dose
- Reduced exacerbations in COPD by 14–28% in landmark trials (UPLIFT, POET-COPD)
- Improved exercise tolerance and reduced dyspnoea in stable COPD
- Reduced rescue inhaler use when added to ICS-LABA in severe asthma (TIOSPIR-asthma trial)
Toepassingen en Indicaties
- COPD maintenance — first-line LAMA at GOLD groups B, E (with or without LABA / ICS depending on phenotype)
- COPD exacerbation prevention
- Add-on for severe asthma not controlled by ICS-LABA (Step 5 GINA)
- Asthma-COPD overlap (ACOS)
Airz Dosage
| Patient | Dosering | Frequentie |
|---|---|---|
| Adults — COPD maintenance | 50 mcg (1 capsule) | Eénmaal daags |
How to Use Airz Properly
- Insert one rotacap into the Rotahaler with the coloured end down.
- Twist sharply — listen for the click.
- Breathe out fully away from device.
- Seal lips around mouthpiece.
- Inhale forcefully and deeply; you should hear the rotacap whir.
- Hold breath 10 seconds, then breathe out slowly.
- Check rotacap is empty; repeat if powder remains.
- For ICS-containing combinations: rinse mouth, gargle, and spit out.
Side Effects of Airz
Common (anticholinergic, dose-related):
- Dry mouth (commonest — typically mild, may improve with sips of water)
- Obstipatie
- Throat irritation, mild cough on inhalation
- Sinusitis, rhinitis, nasopharyngitis
- Mild urinary hesitancy in older men with prostate enlargement
Minder vaak:
- Acute angle-closure glaucoma (rare; care with mist contacting eyes)
- Urinary retention in patients with prostatic obstruction
- Tachycardia, palpitations (less common than with β2 agonists)
- Blurred vision (transient if drug contacts eyes)
- Atrial fibrillation in susceptible older patients
Serious (stop and seek emergency help):
- Severe allergic reaction / anaphylaxis / angio-oedema
- Acute eye pain with red eye, halos around lights, blurred vision (suspected glaucoma — emergency)
- Acute urinary retention
- Paradoxical bronchospasm
Waarschuwingen en voorzorgsmaatregelen
- {$brand} is a controller, not a reliever. Use Asthalin or Levolin for acute breathlessness.
- Use once daily, every day — protective effect is maintained only with consistent dosing.
- Avoid mist contacting the eyes — risk of acute angle-closure glaucoma in predisposed patients (narrow anterior chamber, family history). Seek immediate help if eye pain or vision change occurs.
- Prostatic obstruction: use cautiously in men with benign prostatic hyperplasia or bladder neck obstruction — risk of urinary retention.
- Nierfunctiestoornis: glycopyrronium bromide is largely renally excreted; use cautiously when CrCl <50 ml/min and monitor for systemic anticholinergic effects.
- Zwangerschap en borstvoeding: limited data — use only if benefit clearly outweighs risk.
- Opslag: keep capsules in the original blister with desiccant; do not pre-load multiple capsules.
Contra-indicaties
- Known hypersensitivity to glycopyrronium bromide, atropine derivatives, or formulation excipients
- Severe hypersensitivity to lactose or milk proteins (DPI formulations contain lactose)
- Acute glaucoma — relative contraindication
- Severe symptomatic prostatic obstruction or bladder outlet obstruction — relative
Geneesmiddelinteracties
| Interacting drug | Effect | Wat te doen |
|---|---|---|
| Other anticholinergics (oral atropine, oxybutynin, hyoscine) | Additive dry mouth, urinary retention, constipation | Monitor symptoms — combine cautiously |
| Tricyclic antidepressants | Additive anticholinergic burden | Caution in elderly |
| Antihistamines (1st generation) | Additive anticholinergic effects | Avoid combination if possible |
Opslag
- Store below 25°C in a dry place. Keep desiccant in the bottle.
- Do not store in the bathroom — humidity makes the powder clump and reduces dose delivery.
- Once the strip/blister is opened, use within the period stated on the leaflet (typically 2–3 months).
- Keep out of reach of children.
Gerelateerde alternatieven op MedsBase
- Foracort Inhaler — budesonide + formoterol ICS-LABA
- Seretide Accuhaler — fluticasone + salmeterol ICS-LABA
- Budecort Inhaler — budesonide ICS preventer
- Duova Inhaler — tiotropium + formoterol LAMA-LABA combo
- Triohale Inhaler — tiotropium + formoterol + ciclesonide triple
Veelgestelde vragen
How is glycopyrronium different from tiotropium?
Both are LAMAs for COPD. Glycopyrronium has a faster onset (5 min for partial effect) than tiotropium (1–3 h to peak), but final 24-hour bronchodilation is similar. Glycopyrronium is also the LAMA component in some combination inhalers (Ultibro, Xoterna with indacaterol; Trimbow with formoterol + beclomethasone).
Is Airz the same as Seebri?
Yes — both deliver glycopyrronium 50 mcg per dry-powder capsule. Seebri Breezhaler (Novartis) is the international brand; Airz (Glenmark) is the Indian-market generic. Clinically interchangeable.
Can Airz be used for asthma?
Glycopyrronium is licensed for COPD only — tiotropium has more asthma data and is the LAMA of choice for severe asthma add-on. Discuss with your prescriber.
Why is Airz once daily?
Glycopyrronium has a long airway residence time (~24 h), allowing once-daily maintenance dosing.
Does Airz cause dry mouth?
Yes — the most common LAMA side effect. Usually mild; manage with sips of water, sugar-free gum, good oral hygiene.
Is Airz a rescue inhaler?
No — it is a controller. Keep a SABA (Asthalin, Levolin) for acute attacks.
Can I take Airz during pregnancy?
Limited data — use only if benefit clearly outweighs risk.
What if mist contacts my eyes?
Risk of acute angle-closure glaucoma in predisposed patients. Aim away from eyes; seek emergency care for eye pain or halos around lights.
How does Airz compare to ipratropium (Ipravent)?
Ipratropium is short-acting (4–6 hours, 4× daily). Glycopyrronium is long-acting (24 hours, once daily). Modern COPD management uses LAMAs (long-acting); short-acting ipratropium is reserved for symptomatic relief, COPD exacerbations, or asthma add-on.
More options in Asthma/COPD Treatment
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 50 mcg |
|---|---|
| Hoeveelheid | 30 Rotacap/s, 60 Rotacap/s, 90 Rotacap/s |
| Farmaceutische vorm | Capsule/s |
| Fabrikant | Glenmark Pharma |
| Behandeling | Chronic obstructive pulmonary disease (COPD) |
| Generiek merk | Glycopyrronium bromide |
Airz
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Airz
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