⚡ Quick Answer — What is Bonair Inhaler?
Bonair Inhaler bevat salbutamol (known as albuterol in the United States), a short-acting beta-2 agonist (SABA) that relaxes bronchial smooth muscle to relieve breathlessness, wheezing, and chest tightness in asthma en chronic obstructive pulmonary disease (COPD). Bonair Inhaler is a pressurised metered-dose inhaler (HFA pMDI) van Sun Pharma. Onset of bronchodilation is 1–5 minutes and effect lasts 4–6 uur. Bonair Inhaler is a reliever (rescue) medication, not a controller — needing it more than 3× per week means underlying asthma is not controlled and a preventer (ICS or ICS-LABA) needs stepping up.
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What Is Bonair Inhaler?
Bonair Inhaler is a pressurised metered-dose inhaler (HFA pMDI) geproduceerd door Sun Pharma at WHO-GMP certified facilities. Each inhaler delivers 100 mcg per actuation van salbutamol (the international generic name is albuterol). salbutamol is on the WHO List of Essential Medicines and is the world’s most-used reliever medication for asthma and reversible airflow obstruction.
How Does Bonair Inhaler Work?
salbutamol selectively activates beta-2 adrenergic receptors on the smooth muscle that rings the bronchial airways. Receptor activation raises intracellular cyclic AMP, smooth muscle relaxes, and the airway lumen widens — this is bronchodilation. Bronchodilation begins within 1–5 minutes, peaks at 30–90 minutes, and lasts 4–6 uur. salbutamol also modestly inhibits mast-cell mediator release, reduces plasma exudation from airway capillaries, and improves mucociliary clearance.
Selectivity is dose-dependent: at therapeutic doses, β2 effects predominate; at higher systemic doses (oral tablets, repeated nebulisation), spillover onto β1 receptors causes tachycardia and palpitations, and onto β2 receptors elsewhere causes tremor and hypokalaemia.
Toepassingen en Indicaties
- Acute asthma exacerbations — first-line reliever (rescue) inhaler/nebulisation
- Chronic obstructive pulmonary disease (COPD) — symptomatic relief of acute breathlessness and exercise dyspnoea
- Exercise-induced bronchoconstriction — inhaled 15–30 minutes before exercise
- Bronchospasm with allergen, cold air, or viral exposure
- Anaphylaxis with bronchospasm — adjunct to adrenaline
- Hyperkaliëmie (off-label) — nebulised salbutamol drives K⁺ intracellularly
Belangrijk: Bonair Inhaler is a reliever, not a controller. It does not reduce underlying airway inflammation. Patients using more than the equivalent of one SABA canister per month, or needing a SABA more than three days per week outside of exercise pre-dosing, have poorly-controlled asthma and require step-up to inhaled corticosteroid (ICS) or ICS-LABA combination therapy.
Bonair Inhaler Dosage
| Indicatie | Dosering | Frequentie |
|---|---|---|
| Acute reliever | 100–200 mcg (1–2 puffs) | As needed, max 8 puffs/day |
| Pre-exercise | 100–200 mcg | 15 minutes before exercise |
| Severe attack | 400–600 mcg via spacer | Every 20 minutes ×3, then reassess |
How to Use Bonair Inhaler Properly
- Shake the inhaler and remove the cap.
- Breathe out fully away from the device.
- Sluit de lippen rond het mondstuk.
- Press and inhale slowly over 3–5 seconds.
- Hold breath 10 seconds, then breathe out gently.
- Wait 30 seconds before a second puff if needed.
- Use a spacer for children, elderly, or anyone with coordination difficulty.
Side Effects of Bonair Inhaler
Common (dose-related, settle within 30–60 minutes):
- Fine tremor, especially of the hands
- Palpitations or increased heart rate (typically 10–20 bpm rise)
- Hoofdpijn
- Dry mouth, throat irritation (more common with DPI/MDI)
- Muscle cramps
- Hyperactivity or agitation in young children
Minder vaak:
- Hypokalaemia — especially with high repeat doses, worsened by theophylline, steroids or loop diuretics
- Milde hyperglykemie
- Insomnia if dosed late evening
- Lactic acidosis with very high continuous nebulised doses (rare)
Serious (stop and seek emergency help):
- Severe allergic reaction / angio-oedema / anaphylaxis
- Paradoxical bronchospasm — worsening wheeze immediately after dose
- Cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia)
- Severe hypokalaemia with arrhythmia or muscle weakness
Waarschuwingen en voorzorgsmaatregelen
- Frequent {$brand} use = poor asthma control. Needing a reliever more than 3 days per week (excluding exercise pre-dosing) means the underlying disease is not managed. Step up ICS-based controller therapy.
- Carry your reliever with you — many fatal asthma attacks happen when the inhaler is at home or expired.
- Cardiovasculaire aandoeningen: use cautiously in severe coronary artery disease, arrhythmias, hyperthyroidism, or severe heart failure.
- Diabetes: monitor glucose with repeat high doses.
- Zwangerschap en borstvoeding: salbutamol is used at the lowest effective dose. Uncontrolled asthma is more dangerous to mother and fetus than the drug itself.
- Severe attack red flags (call emergency services): no relief 10 min after a full dose, peak flow <50% of personal best, difficulty speaking in full sentences, blue lips or drowsiness.
Contra-indicaties
- Known hypersensitivity to salbutamol or any formulation excipient
- Tachyarrhythmias (uncontrolled) — relative contraindication
- Phaeochromocytoma — relative contraindication
- Hypertrophic obstructive cardiomyopathy — caution
Geneesmiddelinteracties
| Interagerend geneesmiddel | Effect | Wat te doen |
|---|---|---|
| Niet-selectieve bètablokkers (propranolol, timolooldruppels) | Blokkeren β2-effect — kan ernstige bronchospasmen veroorzaken | Vermijd; schakel indien noodzakelijk over op een cardioselectieve bètablokker |
| Lis- of thiazidediuretica | Additieve hypokaliëmie | Controleer het serumkalium bij hoge doseringen |
| Systemische corticosteroïden | Additieve hypokaliëmie + hyperglykemie | Controleer elektrolyten en glucose |
| Theofylline / aminofylline | Additieve tachycardie en hypokaliëmie | Controleer hartslag en kalium |
| MAO-remmers en tricyclische antidepressiva | Versterken cardiovasculaire effecten | Voorzichtigheid — controleer bloeddruk/hartslag |
| Digoxine | Hypokaliëmie verhoogt digoxine-toxiciteitsrisico | Controleer kalium; meet digoxinespiegel bij symptomen |
Opslag
- Bewaren beneden 25°C, beschermd tegen direct zonlicht en hitte.
- Niet koelen. Niet invriezen.
- Niet in de canule prikken; zelfs een lege canule kan exploderen bij verhitting.
- Buiten bereik van kinderen houden. Gebruik vóór de vervaldatum die op het busje staat afgedrukt.
Gerelateerde alternatieven op MedsBase
- Asthalin Respules — salbutamol nebuliser solution
- Budecort Inhaler — budesonide ICS-preventer
- Foracort Inhaler — budesonide + formoterol ICS-LABA
- Seretide Accuhaler — fluticason + salmeterol ICS-LABA
- Duolin Inhaler — salbutamol + ipratropium combo reliever
Veelgestelde vragen
Is Bonair Inhaler the same as Asthalin or Ventolin?
Yes — all three are 100 mcg salbutamol HFA pressurised metered-dose inhalers. Bonair is Sun Pharma’s brand; Asthalin is Cipla’s; Ventolin is GSK’s. Clinically interchangeable.
How many puffs is safe in 24 hours?
Routine: 1–2 puffs every 4–6 hours, max 8 puffs/day. Acute severe attack: up to 4–10 puffs via spacer under supervision.
When should I switch from reliever to a controller?
Needing your reliever more than three days per week (excluding pre-exercise dosing), having night symptoms more than once a month, or using more than one canister a month — any of these is a signal to add an ICS preventer.
Can I use Bonair Inhaler with a beta-blocker?
Cardioselective β1-blockers are usually OK; non-selective beta-blockers (propranolol) and timolol drops can block salbutamol and trigger severe bronchospasm — avoid where possible.
How long does Bonair Inhaler last?
A 200-actuation canister lasts about 100 days at 2 puffs per day. Track actuations or check the dose counter (if present).
Is Bonair Inhaler safe for pregnant women?
Salbutamol is widely used in pregnancy. Uncontrolled asthma is more dangerous than the drug. Use the lowest effective dose; switch to ICS-LABA controller if needed.
Why am I shaky after using Bonair Inhaler?
Fine tremor is a normal β2 effect, especially with multiple puffs. It settles in 30–60 minutes.
Can I share my inhaler with someone else?
No. The mouthpiece harbours bacteria and viruses; it should not be shared.
How do I clean Bonair Inhaler?
Once a week, remove the metal canister, rinse the plastic actuator with warm water, shake out, and air-dry overnight. Do not put the canister itself in water.
Gerelateerde alternatieven
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