Cerazette
✅ Highly effective contraception
✅ Minimizes menstrual pain
✅ Reduces menstrual bleeding
✅ Suitable for breastfeeding mothers
✅ No estrogen content
Cerazette contains Desogestrel.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
💡 Snel antwoord
Cerazette is een progestin-only pill (POP) die desogestrel 75 mcg. Unlike older “mini-pills”, desogestrel POPs reliably suppress ovulation and have a 12-hour missed-pill window (vs 3 hours for traditional POPs). Taken every day with no tablet-free break. Safer than combined pills for women who smoke, are over 35, have migraine with aura, are breastfeeding, or have VTE risk factors.
What Is Cerazette?
Cerazette is a branded generic desogestrel 75 mcg progestin-only pill (POP) — sometimes called the “mini-pill”. Unlike combined oral contraceptives, POPs contain no estrogen, which makes them safer for women with contraindications to estrogen (smokers over 35, migraine with aura, VTE history, breastfeeding mothers). Manufactured by Organon.
Desogestrel POP is different from older POPs (norethindrone, levonorgestrel-only mini-pills): desogestrel reliably suppresses ovulation in ~97% of cycles, so contraceptive efficacy is similar to combined pills. Older POPs work mainly via cervical mucus and only sometimes suppress ovulation, which is why they require tighter timing.
Genitale herpes (eerste episode):
- Contraception — ~99% effective with perfect use; ~91% with typical use.
- Breastfeeding contraception — POPs do not reduce milk supply; first-line for nursing mothers.
- Contraception when estrogen is contraindicated — smokers over 35, migraine with aura, VTE history, uncontrolled hypertension, breastfeeding.
- Post-partum contraception — can be started immediately after delivery (even in the first few weeks).
- Endometriosis pain — some women respond to continuous POP use.
How to Take Cerazette
- Start on day 1 of your period for immediate contraceptive protection. Starting any other day requires 2 days of backup.
- Neem one tablet every day at the same time. There is no tablet-free week — take continuously, pack after pack.
- Desogestrel POP has a 12-hour missed-pill window. If you remember within 12 hours of the usual time, take the tablet and continue normally. Beyond 12 hours = missed pill.
- When starting a new pack: go straight from the last tablet of one pack to the first tablet of the next. No break.
- Expect unpredictable bleeding patterns in the first 3 months — breakthrough bleeding, spotting, or absent periods are all normal. Persistent heavy bleeding after 6 months needs clinical review.
Missed Pill Rules (Desogestrel POP)
| Scenario | Actie |
|---|---|
| Pill taken less than 12 hours late | Take it. Continue normally. No backup needed. |
| Pill taken more than 12 hours late | Take the missed pill immediately. Continue the rest as normal. Use condoms or abstain for 2 dagen. Consider emergency contraception if unprotected sex in the prior 48 hours. |
| Vomiting within 2 hours of taking pill | Treat as missed pill. Take another from a spare pack if available; use backup for 2 days. |
Opmerking: older POPs (norethindrone-only) have a much tighter 3-hour window. Desogestrel’s 12-hour window is one of its main practical advantages.
Bijwerkingen
Common (transient or adjustable): irregular bleeding (spotting, breakthrough bleeding, or absent periods — any pattern is normal on POPs), breast tenderness, headache, mood changes, acne, reduced libido.
Minder vaak: ovarian cysts (usually transient and resolve without treatment), weight fluctuations, nausea.
Zeldzaam maar belangrijk: ectopic pregnancy (if conception occurs on POPs, ectopic rate is slightly higher than with no contraception — unusual given how effective POPs are). Report severe abdominal pain urgently.
POP vs COC — When to Choose Cerazette
- POP is the right choice: you smoke and are over 35; you have migraine with aura; you have a VTE history; you are breastfeeding; you have uncontrolled hypertension; you dislike estrogen side effects.
- COC is the right choice: you want predictable monthly periods, are being treated for acne / PMDD / heavy periods, have no contraindications to estrogen.
Who Should Not Take Cerazette
- Current or recent breast cancer.
- Active liver disease (hepatitis, cirrhosis, active tumour).
- Unexplained vaginal bleeding — investigate before starting hormonal contraception.
- Known hypersensitivity to desogestrel.
- Confirmed pregnancy.
Geneesmiddelinteracties
- Enzyme inducers reduce POP efficacy: rifampicin, rifabutin, phenytoin, carbamazepine, St John’s Wort, some HIV ARVs. Use backup or switch to non-hormonal method during and 4 weeks after these drugs.
- Antibiotics (non-rifampicin): do NOT reduce POP efficacy. The old advice about backup during all antibiotics is outdated.
Opslag
Store at room temperature (15–25 °C). Keep in original packaging. Away from direct sunlight and moisture. Keep out of reach of children.
Veelgestelde vragen
Will my periods stop on Cerazette?
Unpredictable bleeding is normal on any POP. Some women stop bleeding entirely (common after 6 months); some have irregular spotting; some continue having regular periods. All patterns are safe. Heavy or prolonged bleeding beyond 6 months warrants clinical review.
Can I take Cerazette while breastfeeding?
Yes — POPs are preferred for breastfeeding mothers. They do not reduce milk supply, unlike combined pills. Can be started immediately postpartum.
Is the 12-hour missed-pill window really more forgiving?
Yes. Older POPs (norethindrone, LNG-only) require <3 hour timing. Desogestrel POP’s 12-hour window makes it much more practical for shift workers, travellers, and anyone who sometimes takes pills at inconsistent times.
Can Cerazette be used as emergency contraception?
No. Emergency contraception requires a specific high-dose regimen (levonorgestrel 1.5 mg or ulipristal acetate). Do not use regular POPs for EC — the dose is wrong and timing window is different.
Will Cerazette cause weight gain?
Evidence from placebo-controlled trials shows POPs are weight-neutral for most women. Some report 1–2 kg fluctuations; most stabilise after 3 months.
Can I use Cerazette immediately after childbirth?
Yes — POPs can be started any time postpartum, including immediately after delivery. This is safer than COCs, which should be delayed 6 weeks.
What if I want to switch to a combined pill?
After completing the current POP pack, start the COC on day 1 of your next period (or immediately with 7-day backup). Always check with a clinician that estrogen is now safe for you (if you switched to POP because of a contraindication, that contraindication may still apply).
Does Cerazette protect against STIs?
No. Use condoms for STI protection.
Related Contraceptive Products
- Yasmin (Drospirenone + EE)
- Yaz (Drospirenone + EE 0.02)
- Ovral-L (Levonorgestrel + EE)
- Ovral-G (Norgestrel + EE)
- Loette (LNG + EE ultra-low)
- Duoluton-L (LNG + EE)
- Triquilar (Triphasic LNG + EE)
⚕️ Medische disclaimer: Hormonal contraceptives have contraindications and interactions. Consult a clinician before starting. If you smoke and are over 35, have migraine with aura, a history of VTE, active liver disease, or known cardiovascular disease, combined oral contraceptives may not be safe for you. Emergency contraception is not a substitute for regular birth control.
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| Sterkte | 75 mcg |
|---|---|
| Hoeveelheid | 28 Tablet/s, 56 Tablet/s, 84 Tablet/s, 168 Tablet/s |
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