Flucomet Eye Drop
Flucomet (fluconazole 0.3%) — triazole antifungal eye drop for Candida keratitis and adjunct in filamentous fungal keratitis. Specialist hospital-initiated therapy.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Flucomet Eye Drop?
Flucomet Eye Drop is Fluconazole 0.3%, an ophthalmic antifungal for fungal keratitis (corneal infection). Fluconazole is preferred for Candida species. Fungal keratitis is a sight-threatening emergency requiring urgent ophthalmology review.
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Waarom bestellen bij MedsBase
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What is Flucomet Eye Drop?
Flucomet Eye Drop is manufactured by Sun Pharma and contains Fluconazole 0.3% as a sterile ophthalmic solution. Topical fluconazole is a triazole antifungal compounded for ocular use. It is preferred for Candida and other yeast keratitis, and as adjunct for filamentous fungal disease alongside natamycin.
Hoe het werkt
Fluconazole inhibits fungal cytochrome P450 14α-demethylase (lanosterol demethylase), blocking ergosterol synthesis and disrupting fungal cell membrane integrity. Fluconazole has excellent penetration into ocular tissues and is fungistatic against yeasts, fungicidal at higher concentrations against filamentous fungi.
Indicaties
- Candida keratitis — first-line
- Adjunct to natamycin in mixed or refractory filamentous keratitis
- Endophthalmitis prophylaxis after intraocular surgery in immunocompromised patients
Dosering
1 drop in affected eye(s) every 1–2 hours during the first 3–4 days, then 1 drop every 3–4 hours for the next 14–21 days. Total course typically 4–6 weeks. Specialist supervision is required throughout — fungal keratitis often requires additional therapies (debridement, oral voriconazole, intrastromal injections, or therapeutic keratoplasty).
Bijwerkingen
Local: stinging, burning, conjunctival hyperaemia, blurred vision, eye pain, foreign body sensation, transient dermatitis.
Systemic: minimal from topical use.
Warnings & Contraindications
- Hypersensitivity to azoles
- Concurrent topical steroids — strongly contraindicated in fungal keratitis (accelerates fungal proliferation)
- Pregnancy / breastfeeding — minimal topical absorption; discuss with prescriber
- Always under specialist supervision; fungal keratitis is not amenable to self-management
Opslag
Store at 2–25°C protected from light. Discard 28 days after first opening or as labelled.
Veelgestelde vragen
What causes fungal keratitis?
Trauma involving plant or vegetative material is the classic cause (Fusarium, Aspergillus). Other risk factors: contact lens use with poor hygiene, prolonged topical steroid use, immunosuppression, ocular surface disease.
Why is fungal keratitis so dangerous?
Fungi penetrate deep into corneal stroma; antifungal drugs penetrate poorly through intact epithelium; courses are weeks not days; perforation risk is high. Many cases require therapeutic corneal transplant.
When should I suspect fungal keratitis?
Suspect after agricultural injury, vegetative trauma, in poor steroid-treatment response, or in any progressive corneal infiltrate not improving on antibacterial therapy. Feathery edges, satellite lesions, and a hypopyon (pus in the anterior chamber) are classic signs.
Why must I avoid steroids?
Steroids suppress the immune response that helps clear fungal infection, allowing fungi to proliferate unchecked. Adding steroid to fungal keratitis can devastate the cornea within days. Always confirm bacterial origin before any steroid eye drop.
How long is the treatment?
Typically 4–6 weeks. Fungi are slow-growing and antifungal drugs are slow-acting on them. Premature stopping is the leading cause of recurrence.
Why is the medication an opaque suspension?
Not applicable — fluconazole is a clear solution.
Can I wear contact lenses during treatment?
No. Contact-lens-associated keratitis is a major fungal-keratitis risk factor. Stop lenses entirely and only resume after specialist clearance.
What is voriconazole and when is it added?
Voriconazole is an oral and topical triazole antifungal added when topical natamycin/fluconazole is inadequate. Specialist initiation only — voriconazole has significant drug interactions and requires therapeutic drug monitoring.
Is Flucomet Eye Drop safe in pregnancy?
Topical absorption is minimal. Discuss with your prescriber. Fungal keratitis itself is sight-threatening and treatment is justified when the diagnosis is confirmed.
What if my eye gets worse on Flucomet Eye Drop?
Same-day ophthalmology review. Possibilities include resistant species, mixed infection, need for debridement or intrastromal injection, or progression toward therapeutic keratoplasty.
Other Eye-Care Medications
Customers viewing this product also consider these alternatives in our Oogzorg range:
- Natamet Eye Drops (natamycin)
- Zonat Eye Drop (natamycin)
- Flucomet Eye Drop (fluconazole)
- Zocon Eye Drop (fluconazole)
- Diflucor Eye Drops
Medische Disclaimer
The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.
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| Sterkte | 5 ml |
|---|---|
| Hoeveelheid | 1 Bottle/s, 3 Bottle/s, 6 Bottle/s |
| Farmaceutische vorm | Eye Drop/s |
| Fabrikant | Sun Pharma |
| Behandeling | Oogzorg |
| Generiek merk | Fluconazole |
Flucomet Eye Drop
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