Glyco Cream

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What Is Glyco Cream?

Glyco Cream is a topical glycolic acid 6% and 12% cream from Healing Pharma, supplied in a 30 g tube. Glycolic acid is a naturally-occurring alpha-hydroxy acid (AHA) found in sugarcane, grapes, and other plants. It has the smallest molecular size of the AHA family (molecular weight ~76 Da), which gives it the deepest skin penetration and the strongest exfoliating effect of the common cosmetic AHAs (glycolic > lactic > mandelic > malic > tartaric > citric). It has been in cosmetic and dermatological use since the late 1980s and is one of the most-studied topical exfoliants.

The 6% concentration is suited to daily-use maintenance products; the 12% concentration is a stronger formulation used for targeted problem skin (acne, PIH, keratosis pilaris) under the same twice- to three-times-weekly application schedule. Dermatologist-administered glycolic acid peels use much higher concentrations (20-70%) under controlled conditions in clinic.

How Does Glyco Cream Work?

• Corneodesmosome disruption — glycolic acid weakens the protein bonds (corneodesmosomes) that hold the outermost dead skin cells (corneocytes) together. Those cells shed more readily, exposing fresher skin underneath. This is the primary exfoliant mechanism.
• Stimulation of basal epidermal turnover — the faster surface shedding signals the basal layer to increase keratinocyte turnover, producing a thinner, more uniform stratum corneum.
• Dermal collagen stimulation at higher strengths — glycolic acid at 8-12% or higher triggers modest increase in collagen I and III synthesis by fibroblasts in the papillary dermis, contributing to fine-line improvement over weeks of consistent use.
• Pigmentation effect — faster shedding of pigmented corneocytes and increased keratinocyte turnover reduces the residence time of melanin in the epidermis. This is why glycolic acid helps PIH and uneven tone.
• Comedolytic effect — by thinning the stratum corneum at the follicular infundibulum, glycolic acid helps prevent the microcomedones that seed acne lesions.
• pH-dependent potency — free-acid glycolic acid (low pH, ~3.5) is more active than neutralised (partially-buffered) formulations. A well-formulated 6-12% cream at pH 3.5-4.0 is clinically useful; the same % at neutral pH is much less effective.

Begin: subtle improvement in texture and glow appears within 2-4 weeks; visible improvement in fine lines and superficial pigmentation at 8-12 weeks; maximum benefit at 16-24 weeks of consistent use + sunscreen.

When Glyco Cream Is Used

• Mild-moderate acne — particularly comedonal and PIH-dominant acne
• Post-inflammatory hyperpigmentation (PIH) from acne, insect bites, contact dermatitis, minor injury
• Photodamage and photo-ageing — rough texture, early fine lines, enlarged pores, dullness
• Sun-induced pigmentation — freckles, solar lentigines
• Mild melasma — as adjunct to other depigmenting agents
• Keratosis pilaris (rough bumpy skin on outer arms/thighs)
• Rough elbows, knees, hands
• Maintenance routine between dermatology-administered glycolic acid peels

Glyco Cream is NOT voor:

• Active rosacea flare — will worsen inflammation
• Acute eczema, contact dermatitis, sunburn, broken skin
• Just-waxed, threaded, or lasered skin — wait 7-14 days
• Immediately after chemical peel, dermabrasion, microdermabrasion — wait at least 2 weeks
• Open cystic acne or deep nodular lesions — will not help; see a dermatologist for proper acne management
• Severe melasma — will only partly help; needs combined HQ/tretinoin or specialist procedural options

Glyco Cream How to Apply

1. Evening routine: cleanse the skin with a mild cleanser; pat completely dry. Wet skin amplifies the sting.
2. Wait 15-20 minutes after cleansing before applying, to let skin barrier recover and pH normalise.
3. Apply a thin, pea-sized layer to the face (or target area). Avoid eyelids, lips, corners of nose, and any broken or inflamed skin. A rice-grain amount is enough for one cheek.
4. Expect mild stinging for 2-5 minutes on the first few applications; it settles over 1-2 weeks as tolerance builds.
5. Starting schedule: 2-3 nights per week for the first 2 weeks. Build to alternate nights if well tolerated. Most users settle on 3-4 nights per week as a maintenance routine.
6. Skip nights when you use retinoid (tretinoin, adapalene) — do NOT use AHA + retinoid the same night.
7. Morning routine (non-negotiable): cleanse, moisturise, broad-spectrum SPF 50+ sunscreen every morning, re-apply every 2-3 hours of UV exposure. AHAs increase UV sensitivity and skipping sunscreen actively worsens your skin.
8. Expected results: texture and glow at 2-4 weeks, tone/pigmentation at 8-12 weeks, fine-line improvement at 12-24 weeks.

Kinderen: not typically used under 14. Zwangerschap en borstvoeding: low-concentration glycolic acid is generally considered acceptable; higher strengths (12%+) have limited pregnancy data and are typically paused during pregnancy — discuss with your obstetrician or dermatologist.

Bijwerkingen

• Common (mild, expected): transient stinging on application, mild redness, dryness, flakiness, peeling in the first 1-2 weeks of use
• Minder vaak voorkomend: irritant contact dermatitis, worsening of rosacea, acneiform eruption
• Zeldzaam: allergic contact dermatitis, significant chemical irritation/burn if left on too long or applied to broken skin
• Paradoxical PIH — if skin becomes severely irritated, it can develop reactive hyperpigmentation. Use sparingly; do not push tolerance aggressively.
• Fotosensitiviteit — the AHA-treated skin is more UV-sensitive for up to a week after stopping; daily SPF 50+ for at least that long

Contra-indicaties & waarschuwingen

• Known hypersensitivity to glycolic acid or any other AHA
• Active rosacea flare
• Active eczema, atopic dermatitis flare, contact dermatitis, acute sunburn, broken skin
• Just-waxed, threaded, or lasered skin (wait 7-14 days)
• Recent chemical peel / dermabrasion / microdermabrasion (wait 2 weeks)
• On isotretinoin therapy or within 6 months of finishing an oral isotretinoin course — skin is abnormally fragile; specialist dermatology advice first
• High strengths (>10%) in pregnancy without specialist advice

Geneesmiddelinteracties

• Topical retinoids (tretinoin, adapalene, tazarotene) — do NOT apply same night; alternate nights is standard. Morning AHA + night retinoid is an alternative schedule.
• Benzoyl peroxide — additive irritation; separate by 30 minutes or use on alternate applications
• Other AHAs and BHA (salicylic acid) — do not stack multiple exfoliants at the same application
• Hydroquinone or other depigmenting actives — combine with caution; alternating nights works well for melasma/PIH
• Vitamin C serums (L-ascorbic acid) — both low-pH products, additive stinging; separate morning vs night, or alternate days
• Prescription photosensitisers (oral doxycycline, isotretinoin, amiodarone) — additive photosensitivity; extra rigorous sun protection

Opslag en houdbaarheid

Store Glyco Cream below 25°C in the original tube, away from direct sunlight and humidity. Replace cap tightly after use. Keep out of reach of children. Use within 6 months of first opening or before the printed expiry — glycolic acid loses potency over extended time at room temperature, and the sting and benefit both fade.

Veelgestelde vragen

How often should I use Glyco Cream?

Start at 2-3 nights per week for the first 2 weeks. If tolerated, build to alternate nights. Most users settle at 3-4 nights per week as a maintenance routine. Nightly use is possible only for skins with high AHA tolerance and usually only at the 6% strength — not recommended as a starting frequency.

Can I use Glyco Cream with tretinoin?

Yes, on alternate nights. Do not apply both on the same night — the irritation compounds and you will develop peeling, redness and potentially reactive PIH. Alternate-night AHA + retinoid is a standard combination for acne with PIH. Always with daily SPF 50+.

Why does Glyco Cream sting?

Glycolic acid is a low-pH product (pH ~3.5 for a well-formulated free-acid cream). Low pH on skin nerve endings triggers the acute stinging sensation. This is normal, transient (2-5 minutes), and settles as tolerance builds over 1-2 weeks. If it lasts >30 minutes, causes frank burning, or produces lasting redness/rash, stop and see a dermatologist.

Do I really have to wear sunscreen every day?

Yes. AHA-treated skin is more UV-sensitive for up to a week after the last application. Without daily broad-spectrum SPF 50+, you are actively creating new sun damage and pigmentation faster than the AHA is clearing old damage. Sunscreen is more important than the cream. This is the single biggest reason AHA regimens “do not work” for some users — they are skipping daily sun protection.

Can I use Glyco Cream if I have rosacea?

Not during an active flare. In controlled rosacea, low-strength glycolic acid occasionally helps smooth texture, but it should only be attempted under dermatology direction and started at the lowest strength and frequency. The 6% strength is safer to trial than 12% in rosacea.

Can I use Glyco Cream on my body (arms, legs, back)?

Yes — glycolic acid is very useful on keratosis pilaris (rough bumps on outer arms/thighs), rough heels/elbows, body acne, and back hyperpigmentation. Apply after showering to dry skin; the skin on trunk and limbs is thicker than facial skin and tolerates higher strength better. Daily sunscreen on exposed body areas still applies.

Is Glyco Cream safe in pregnancy?

Low-concentration glycolic acid (6% or lower) is generally considered acceptable in pregnancy because systemic absorption is very low. Higher strengths (12%+) have limited pregnancy data and are typically paused during pregnancy. Discuss with your obstetrician if unsure.

Where can I order Glyco Cream online?

You can order Glyco Cream from MedsBase in standard pack sizes (30 g tube). Orders ship worldwide with discreet packaging. Low-concentration glycolic acid creams (up to 10%) are over-the-counter in most jurisdictions; higher concentrations may require a prescription in some countries.

Gerelateerde producten op MedsBase

• A-Ret Gel (tretinoin) — prescription topical retinoid; alternate-night combination is standard
• Retino-A Cream (tretinoin) — tretinoin cream form
• Melalite Forte Crème — hydroquinone for focal pigmentation (alternate-night combination works well for PIH)
• Kojiglo Forte Cream — kojic acid mono-active depigmenter
• Epilite — non-HQ depigmenter

Handige lectuur: MedsBase klantbeoordelingen.

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