Ecosprin
Ecosprin is USV’s aspirin 75/150 mg tablets — the reference antiplatelet for cardiovascular secondary prevention. Irreversible COX-1 inhibitor, saturates platelet COX at 75-100 mg; 7-10 day effect duration per dose. 20-25% reduction in recurrent CV events after MI/stroke/PAD. Primary prevention largely abandoned since 2018 (ARRIVE/ASPREE/ASCEND). Combine with PPI if GI risk. Avoid in children <16 with viral illness (Reye syndrome).
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Ecosprin?
Ecosprin is 75 / 150 mg aspirin tablets from USV — antiplatelet (irreversible COX-1 inhibitor). Aspirin (acetylsalicylic acid) was introduced by Bayer in 1897 and became the first modern antiplatelet with the ISIS-2 trial (1988) demonstrating 23% mortality reduction at day 35 post-MI. irreversibly acetylates platelet COX-1, blocking thromboxane A2 synthesis for the platelet’s 7-10 day lifespan. Single low dose (75-100 mg) saturates COX-1 inhibition. Dosing: Standard antiplatelet dose 75-100 mg daily (low-dose, “baby” aspirin). ACS loading 300 mg single dose. Bleeding risk: GI bleeding risk rises 2-4 fold; major bleeding ~0.5-1%/year on monotherapy. Add PPI for high GI risk patients. Anticoagulant and antiplatelet selection is individualised to diagnosis, bleeding risk, renal function, and drug interactions. Specialist or family-physician supervision is standard.
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What Is Ecosprin?
Ecosprin is 75 / 150 mg aspirin tablets from USV, supplied in 28-84 tablets. Aspirin (acetylsalicylic acid) was introduced by Bayer in 1897 and became the first modern antiplatelet with the ISIS-2 trial (1988) demonstrating 23% mortality reduction at day 35 post-MI.
How Aspirin Works
Aspirin irreversibly acetylates platelet COX-1, blocking thromboxane A2 synthesis for the platelet’s 7-10 day lifespan. Single low dose (75-100 mg) saturates COX-1 inhibition.
Approved Uses
- Secondary prevention after MI, stroke, TIA, or PAD — 20-25% reduction in recurrent CV events
- Acute coronary syndrome — loading dose 300 mg then 75-100 mg daily
- Atriumfibrilleren — inferior to anticoagulation; largely displaced by DOACs and warfarin
- Primary prevention — largely abandoned since 2018 (ARRIVE, ASPREE, ASCEND) showed net harm in low-risk primary prevention; specific niches remain
Dosage
Standard antiplatelet dose 75-100 mg daily (low-dose, “baby” aspirin). ACS loading 300 mg single dose.
Bleeding Risk and Monitoring
Bleeding risk: GI bleeding risk rises 2-4 fold; major bleeding ~0.5-1%/year on monotherapy. Add PPI for high GI risk patients.
No routine blood monitoring required. Dose saturates COX-1 inhibition at 75-100 mg; higher doses add GI toxicity without cardiovascular benefit.
Bijwerkingen
- Dyspepsia, GI irritation
- GI bleeding (major 0.5-1%/year)
- Tinnitus at high doses
- Bronchospasm in aspirin-sensitive asthmatics (3-10% of asthmatics)
- Nasal polyps exacerbation in Samter triad
- Reye syndrome in children <16 with viral illness (contraindicated)
Contra-indicaties
- Active peptic ulcer or recent GI bleed
- Haemophilia or severe bleeding disorder
- Children <16 with viral illness (Reye syndrome risk)
- Severe aspirin hypersensitivity / Samter triad (relative)
- Third-trimester pregnancy (closes ductus arteriosus); low-dose is used earlier for pre-eclampsia prevention
Geneesmiddelinteracties
- NSAIDs (ibuprofen, diclofenac) — compete for COX-1 binding and can blunt aspirin’s antiplatelet effect; avoid chronic NSAID co-therapy or take NSAID 2 hours after aspirin.
- Anticoagulants — additive bleeding; combination (e.g. aspirin + warfarin or aspirin + DOAC) is used in specific situations (AF with recent stent) but requires specialist supervision.
- SSRIs — additive GI bleeding risk (SSRIs affect platelet serotonin).
- Methotrexaat — aspirin reduces renal clearance; monitor.
- Other antiplatelets (clopidogrel, prasugrel, ticagrelor) — dual antiplatelet therapy is standard after ACS/PCI; bleeding risk approximately doubled vs monotherapy.
Opslag
Store Ecosprin below 25°C. Keep out of reach of children.
Veelgestelde vragen
Do I need blood tests on Ecosprin?
No routine blood tests for efficacy. General health screening as clinically indicated.
What should I do if I cut myself while on Ecosprin?
Apply firm direct pressure for 15-20 minutes without checking. Most minor cuts stop normally; bleeding that continues >20 minutes or bleeds through multiple dressings warrants urgent medical review. Report any black or bloody stools, bright red rectal bleeding, haematuria, unexplained bruising, nosebleeds >15 minutes, or menstrual bleeding much heavier than usual.
Can I take Ecosprin in pregnancy?
Discuss with your clinician; low-dose aspirin is standard in high pre-eclampsia risk but avoided in third trimester.
What if I need surgery?
Inform the surgical team well in advance. Antiplatelet continuation/holding decision depends on procedure and thrombosis risk; do not stop without specialist input after recent stents.
Where can I buy Ecosprin online?
You can buy Ecosprin (aspirin 75 / 150 mg, 28-84 tablets) from MedsBase with discreet packaging and worldwide shipping.
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| Sterkte | 75 mg, 150 mg |
|---|---|
| Hoeveelheid | 28 Tablet/s, 56 Tablet/s, 84 Tablet/s |
| Farmaceutische vorm | Tablet/s |
| Fabrikant | USV Pvt Ltd |
| Behandeling | Prevention of heart attack and stroke |
| Generiek merk | Aspirine |
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