Susten Injection
✅ Maintains a healthy uterine lining
✅ Supports the progress of pregnancy
✅ Helps regulate the menstrual cycle
✅ Restores hormonal balance
contains Progesterone
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
💡 Snel antwoord
Susten Injection is natural progesterone 100 mg/mL in oil, administered as an intramuscular injection. Primary use: luteal phase support in IVF cycles and selected cases of threatened miscarriage. Intramuscular progesterone has the highest uterine bioavailability of any route. Administered daily or alternate days by a clinician or trained patient. This product is not indicated for menopausal HRT — oral or transdermal progesterone is standard for that use.
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What Is Susten Injection?
Susten Injection is a branded generic of natural progesterone 100 mg/mL formulated in oil (typically sesame or castor oil) for intramuscular injection. It is a bioidentical form of the progesterone hormone naturally produced by the corpus luteum and placenta. Manufactured by Sun Pharma.
Category note: while this product appears in the HRT category, IM progesterone is primarily used for fertility and early pregnancy support — not typical menopausal HRT. For menopause, oral (endogest, susten-capsule) or micronized progesterone is more convenient.
Genitale herpes (eerste episode):
- Luteal phase support in IVF — 50–100 mg IM daily starting on day of egg retrieval, continued through early pregnancy (up to week 10–12).
- Frozen embryo transfer (FET) — programmed cycle with IM progesterone for endometrial preparation.
- Selected cases of threatened miscarriage — typically in women with ≥3 prior miscarriages and current bleeding (PRISM trial criteria).
- Progesterone challenge test — to evaluate secondary amenorrhoea.
- Secondary amenorrhoea and functional uterine bleeding — less common; oral progesterone is usually preferred.
How to Use Susten Injection
- Warm the vial in your hands to reduce pain and improve flow through the needle.
- Use a 21–22 gauge needle for injection (larger than standard insulin needle because of the oil vehicle).
- Inject into the upper outer quadrant of the buttock (gluteal region) or outer thigh. Alternate sides daily.
- Inject slowly to minimise pain; expect the site to be sore or lumpy for several days.
- Apply warmth after injection (warm pack) to aid absorption and reduce lumps.
- Rotate sites consistently — daily injections in the same spot produce painful nodules.
- Follow fertility clinician’s timing: typically daily in IVF cycles, continuing through week 10–12 of confirmed pregnancy.
Bijwerkingen
Injection-site effects (very common): pain, soreness, bruising, redness, nodule formation, rarely sterile abscess.
Systemic (common): fatigue, drowsiness, breast tenderness, mood changes, bloating, breakthrough bleeding.
Zeldzaam ernstig: allergic reaction to oil vehicle (sesame-allergic patients must use castor-oil variant), acute pancreatitis, cholestasis, jaundice, thrombosis.
Who Should Not Use Susten Injection
- Known allergy to sesame oil or castor oil (depending on vehicle)
- Active severe liver disease
- Known or suspected breast cancer
- Active VTE or history of thrombophilia
- Undiagnosed vaginal bleeding
- Ectopic pregnancy (do not continue once confirmed)
Oral vs IM vs Vaginal Progesterone
| Route | Advantages | Drawbacks |
|---|---|---|
| Oral (endogest, susten-capsule) | Convenient, sleep benefit | First-pass metabolism, drowsiness |
| Vaginal (off-label oral, gels, pessaries) | High uterine delivery, less drowsiness | Messy, daily dosing |
| IM (Susten Injection) | Highest uterine levels, most reliable absorption | Painful, lumpy sites, requires training |
Opslag
Store at room temperature (15–25 °C / 59–77 °F). Do not refrigerate (oil hardens). Protect from light. Discard any unused portion after withdrawal if single-use ampoule.
Veelgestelde vragen
Why is IM progesterone so painful?
The oil vehicle requires a large-bore needle. The oil takes time to absorb, producing a palpable nodule for days. Rotating injection sites, warming the vial before injection, and applying warmth afterwards all help.
Can I take oral Susten Injection instead?
For IVF/fertility use, IM is often preferred for bioavailability and reliability. Some clinics use vaginal suppositories as a less painful alternative. For menopausal HRT, oral is the standard. Discuss with your fertility specialist or gynaecologist.
Is IM progesterone for menopausal HRT?
Typically no — oral or vaginal is used. IM is too painful and impractical for long-term HRT. This product in the HRT category is more commonly used for fertility / early pregnancy support.
Can I inject this myself?
With training, yes. Many women undergoing IVF self-inject IM progesterone daily at home. Alternatively, a nurse or partner can administer. Request training from your fertility clinic.
How long do I continue Susten Injection in IVF?
Typically from egg retrieval through confirmed pregnancy at ~week 10–12, when the placenta takes over progesterone production. Exact duration per fertility clinic protocol.
Wat als ik een dosis vergeet?
Take it as soon as you remember, unless it is close to the next scheduled dose. Contact your fertility clinic — luteal phase consistency matters.
Are there side effects that warrant stopping?
Sterile abscess at injection site, severe allergic reaction, signs of thrombosis (leg pain/swelling, chest pain, shortness of breath), jaundice, severe mood changes. Seek urgent care.
Can I travel with Susten Injection?
Yes — carry in original packaging with a clinician letter for customs. Needles require clinician documentation in some jurisdictions. Room-temperature storage makes travel easier than refrigerated drugs.
Related Hormone & Women’s Health Products
- Premarin (Conjugated Estrogens)
- Premarin Cream (Vaginal Estrogen)
- Progynova (Estradiol Valerate)
- Endogest (Progesterone 100 mg)
- Gestoford (Progesterone 100 mg)
- Gestheal (Progesterone 200 mg)
- Susten Capsule (Progesterone)
⚕️ Medische disclaimer: Information is educational and does not replace medical advice. Hormone therapies carry specific risks (breast cancer, VTE, stroke, endometrial cancer if unopposed estrogen) — consult a clinician before starting, stopping, or changing any hormone medication. Individual risk–benefit depends on personal and family medical history.
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More options in Fertility Supplements for Women
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 100mg/ml * 1ml, 100mg/ml * 2ml |
|---|---|
| Hoeveelheid | 5 Injection/s, 10 Injection, 15 Injection |
| Farmaceutische vorm | Injection/s |
| Fabrikant | Sun Pharma |
| Behandeling | Female infertility, Hormone replacement therapy |
Susten Injection
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Susten Injection
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