Terbicip
✅ Fights fungal infections
✅ Relieves itching and burning
✅ Promotes healthy nails
✅ Treats athlete’s foot
✅ Clears skin infections
Terbicip contains Terbinafine.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
💡 Snel antwoord
Terbicip is terbinafine 250 mg oral tablet — an allylamine antifungal and the first-line oral treatment for dermatophyte onychomycosis (toenail / fingernail fungus) and tinea capitis. 250 mg once daily × 6 weeks (fingernails) or 12 weeks (toenails). Concentrates in skin and nails — persists in the nail bed for weeks after the last dose. Best cure rates of any oral antifungal for dermatophyte infections (~76%). LFT monitoring required; rare but serious hepatotoxicity. Not effective against Candida or non-dermatophyte yeasts — confirm dermatophyte before starting.
WHO-GMP
gecertificeerde fabrikant
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Waarom bestellen bij MedsBase
Onze generieke medicijnen zijn afkomstig van WHO-GMP gecertificeerde fabrikanten en worden wereldwijd verzonden in discrete, eenvoudige verpakkingen — geen medicijnnaam op de buitenkant van het pakket. Betalingen met kaart worden verwerkt via een gereguleerde processor (betalingsoverzichten vermelden een gereguleerde kaartbetalingprocessor — nooit “MedsBase” of een medicijnnaam). Crypto en SEPA bankoverschrijvingen worden ook geaccepteerd. Elke bestelling wordt ondersteund door ons Reshipment Assurance Policy.
Discrete verpakking
ongemarkeerde envelop
Wereldwijde verzending
naar de meeste landen
🔒 Why order Terbicip from MedsBase
- WHO-GMP gecertificeerde fabrikant — afkomstig uit een gereguleerde faciliteit, complete verpakking met batchnummer en vervaldatum.
- Discrete verpakking — gewone envelop, geen medicatienaam aan de buitenkant.
- Wereldwijde verzending naar de meeste landen met Reshipment Assurance.
- Loyaliteitspunten — 1 punt per $1 uitgegeven (peptiden/verzendkosten uitgezonderd); 100 punten = $5 korting op uw volgende bestelling.
Toepassingen & indicaties
Terbicip (terbinafine 250 mg, Cipla) is the standard oral therapy for dermatophyte fungal infections of the skin and nails. It is fungicidal against dermatophytes (Trichophyton, Epidermophyton, Microsporum), fungistatic against most Candida species (so not used for yeast infections), and active against some moulds.
| Indicatie | Standaard behandelingsschema |
|---|---|
| Onychomycosis — fingernails | 250 mg once daily × 6 weeks |
| Onychomycosis — toenails | 250 mg once daily × 12 weeks |
| Tinea capitis (scalp ringworm) — adults | 250 mg once daily × 4 weeks |
| Tinea capitis — children > 4 y | Weight-based: 62.5 mg (10–20 kg) / 125 mg (20–40 kg) / 250 mg (> 40 kg) once daily × 4 weeks |
| Tinea pedis / cruris / corporis (extensive or topical-refractory) | 250 mg once daily × 2–6 weeks |
| Tinea manuum | 250 mg once daily × 2–4 weeks |
Hoe in te nemen
- Take with or without food — absorption is not significantly affected.
- Take at the same time each day to maintain steady plasma levels.
- Do not stop early — even when the visible nail looks normal, dermatophytes may persist deep in the nail matrix.
- The dead, fungus-affected nail will keep growing out for 9–12 months after a successful 12-week course. This is normal.
Hoe het werkt
Terbinafine inhibits squalene epoxidase — an enzyme earlier in the ergosterol biosynthesis pathway than the CYP51 target of azoles. This causes squalene to accumulate inside the fungal cell (toxic effect) AND ergosterol depletion (membrane disruption) — the dual mechanism is why terbinafine is fungicidal against dermatophytes. Highly lipophilic — concentrates in stratum corneum, hair follicles, sebum, and nail at concentrations many times plasma. Persists in the nail for weeks after dosing.
Bijwerkingen & monitoring
| Frequentie | Effects |
|---|---|
| Very common (≥10%) | Headache, gastrointestinal symptoms (nausea, abdominal pain, diarrhoea), mild rash |
| Vaak voorkomend | Taste disturbance / loss of taste (~3% — usually reversible over weeks to months but can be persistent), arthralgia, myalgia |
| Minder vaak | Hepatic enzyme rise, depression, peripheral neuropathy |
| Zeldzaam maar ernstig | Severe hepatotoxicity (idiosyncratic, can be fatal — discontinue if AST/ALT > 3× ULN or any symptoms), severe skin reactions (SJS, TEN, AGEP), drug-induced lupus, agranulocytosis, neutropenia |
Geneesmiddelinteracties
Terbinafine has fewer interactions than the azoles, but is a moderate inhibitor of CYP2D6:
| Drug class | Effect | Actie |
|---|---|---|
| Tricyclic antidepressants (amitriptyline, nortriptyline) | Levels rise — anticholinergic / cardiac toxicity | Reduce dose; monitor |
| SSRIs / SNRIs (paroxetine, fluoxetine, venlafaxine, duloxetine) | Levels rise | Monitor for serotonin syndrome / side effects |
| Beta-blockers (metoprolol, propranolol, carvedilol) | Levels rise — bradycardia, hypotension | Monitor pulse / BP |
| Antiarrhythmics (flecainide, propafenone) | Levels rise — proarrhythmia | Avoid combination if possible |
| Codeine, tramadol | Reduced analgesic effect (CYP2D6 activates these) | Switch to morphine or non-opioid analgesia |
| Rifampicine | Terbinafine clearance increased | Increase terbinafine dose 50% or extend duration |
| Cimetidine | Reduces terbinafine clearance | No dose change usually needed |
| Caffeine | Levels rise — jitteriness | Reduce caffeine intake |
Who should not take oral terbinafine
- Active or chronic liver disease — particularly cirrhosis, active hepatitis.
- Severe renal impairment (CrCl < 50 mL/min — limited data).
- Hypersensitivity to terbinafine.
- Caution in patients with autoimmune disease — terbinafine can precipitate cutaneous lupus.
- Caution in pregnancy and breastfeeding (limited data; defer treatment of onychomycosis until after).
Zwangerschap & borstvoeding
Limited human pregnancy data. Animal studies do not show teratogenicity. Onychomycosis is not life-threatening — defer treatment until after pregnancy and breastfeeding. Terbinafine is excreted in breast milk; not recommended during breastfeeding except if benefit clearly outweighs risk.
Veelgestelde vragen
How long until my toenail looks normal?
The drug clears the fungus within the 12-week course but the dead, discoloured nail keeps growing out from the cuticle. Toenails take 9–12 months to look fully normal; fingernails 4–6 months. Photo at month 0, 3, 6, 12 to track objectively.
Why do I have to confirm it’s a dermatophyte first?
Terbinafine is highly active against dermatophytes (Trichophyton, Epidermophyton) but only weakly active against Candida and most non-dermatophyte moulds. ~50% of nail discolouration is something other than dermatophyte fungus (psoriasis, lichen planus, trauma, melanoma). A nail clipping for microscopy and culture (or PCR) before starting saves 12 weeks of useless therapy.
Why am I tasting metal / can’t taste my food?
Taste disturbance affects ~3% of patients on oral terbinafine. The mechanism is not fully understood. It is usually reversible over weeks to a few months after stopping, but ~10% of cases can be persistent or permanent. If taste change starts during therapy, balance the impact against the cure rate — sometimes worth completing the course, sometimes worth switching to itraconazole.
Terbinafine vs itraconazole — which one for my toenail?
Terbinafine is first-line for dermatophyte onychomycosis: higher cure rate (~76% vs ~63%), fewer drug interactions, no acid-absorption rule. Itraconazole pulse is preferred for non-dermatophyte mould or mixed Candida onychomycosis, or when terbinafine is contraindicated.
Can I drink alcohol while taking terbinafine?
Both alcohol and terbinafine are processed by the liver. Heavy drinking raises hepatotoxicity risk. Light intake is generally accepted; avoid binge-drinking and cut alcohol entirely if you have any pre-existing liver concern. A 12-week treatment course is a reasonable time to reduce alcohol intake.
What about my child with scalp ringworm?
Terbinafine is licensed for tinea capitis in children > 4 years (weight-based dosing). For Trichophyton tonsurans (the common UK / US cause) it is first-line — 4-week course, higher cure rate than griseofulvin and shorter duration. For Microsporum canis, griseofulvin is preferred.
I’ve had alopecia areata before — does terbinafine make it worse?
Terbinafine is rarely associated with new-onset hair loss (telogen effluvium). Pre-existing alopecia areata is not a contraindication. If significant hair loss develops, discuss with a dermatologist.
Why do my muscles ache on terbinafine?
Myalgia and arthralgia are recognised side effects (~5%). Usually mild and resolve on continuation. Severe muscle pain, dark urine, or weakness — stop the drug and seek medical advice (rare rhabdomyolysis or drug-induced myopathy).
Can I exercise on terbinafine?
Yes — normal exercise is fine. The mild myalgia some patients experience is not exercise-related. If you develop unusual leg pain or dark urine after exercise, hold the drug and get a CK level.
Is Terbicip the same as Lamisil?
Yes — Lamisil is the original Novartis brand of terbinafine. Terbicip contains the same active ingredient, manufactured by Cipla under WHO-GMP. Bioequivalent.
Opslag
Store tablets at 15–30 °C, away from moisture and light. Keep in original blister. Do not use after expiry. Keep out of reach of children.
Andere antischimmelmiddelen die u mogelijk interesseren
If Terbicip is unavailable, here are alternatives — same molecule from a different manufacturer, plus options for indications where terbinafine is not first-line.
- Zimig (terbinafine 250 mg) — First-line for dermatophyte onychomycosis; ~76% cure rate.
- Sporanox (itraconazole 100 mg) — Pulse therapy for non-dermatophyte mould or mixed Candida onychomycosis.
- Grisovin FP (griseofulvin) — Tinea capitis caused by Microsporum (paediatric).
- Loceryl (amorolfine 5%) — Topical lacquer for mild distal-edge nail fungus.
- Zocon (fluconazol 150 mg) — Standard oral therapy for Candida (vaginal, oral, oesophageal thrush).
Meer opties in Anti Schimmel
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 250 mg |
|---|---|
| Hoeveelheid | 7 Tablet/s, 14 Tablet/s, 21 Tablet/s, 28 Tablet/s |
Terbicip
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