Yasmin
✅ Prevents Pregnancy
✅ Regulates Menstrual Cycle
✅ Reduces Menstrual Cramps
✅ Decreases Acne Breakouts
✅ Prescribed Birth Control
Yasmin contains Drospirenone and Ethinylestradiol.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
Quick Answer — What is Yasmin?
Yasmin is a combined oral contraceptive pill containing drospirenone 3 mg + ethinylestradiol 0.03 mg, manufactured by Bayer. Taken once daily for 21 days followed by a 7-day break, it prevents pregnancy with over 99% efficacy when used correctly. Drospirenone has mild anti-androgen and anti-mineralocorticoid activity, making Yasmin particularly useful for women with acne or premenstrual symptoms.
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What Is Yasmin?
Yasmin is a combined oral contraceptive pill (COC) containing drospirenone 3 mg en ethinylestradiol 0.03 mg per tablet. Manufactured by Bayer, it has been one of the most widely prescribed oral contraceptives worldwide since its introduction in 2001. Each 21-tablet blister pack is taken once daily for 21 consecutive days, followed by a 7-day pill-free interval during which a withdrawal bleed occurs. A new pack is then started regardless of whether the bleed has finished.
When taken correctly, Yasmin has a failure rate below 1 per 100 women-years — making it one of the most reliable reversible methods of contraception available. Beyond pregnancy prevention, Yasmin is also used to regulate menstrual cycles, reduce menstrual cramping, manage premenstrual dysphoric disorder (PMDD) and treat moderate acne in women who also require contraception.
Uses of Yasmin
- Oral contraception — prevention of pregnancy; the primary indication.
- Moderate acne vulgaris — in women who also want contraception; drospirenone’s anti-androgen activity reduces sebum production.
- Premenstrual dysphoric disorder (PMDD) — improves mood symptoms in the premenstrual phase.
- Menstrual cycle regulation — corrects irregular or unpredictable periods.
- Heavy menstrual bleeding and dysmenorrhoea — reduces bleeding volume and cramp intensity.
- Off-label: polycystic ovary syndrome (PCOS) — manages androgenic symptoms (acne, hirsutism).
How Yasmin Works
Yasmin prevents pregnancy through three complementary mechanisms. First, it suppresses ovulation — the continuous presence of synthetic oestrogen and progestogen disrupts the hormonal signals from the hypothalamus and pituitary that normally trigger egg release each month. Second, it thickens cervical mucus, creating a barrier that impedes sperm entry into the uterus. Third, it thins the endometrial lining, reducing the likelihood that a fertilised egg could implant.
The drospirenone component is distinctive. Unlike older progestogens (levonorgestrel, norethindrone), drospirenone is derived from spironolactone and has anti-mineralocorticoid activity (counteracting oestrogen-induced water retention) and mild anti-androgen activity (blocking the acne-promoting effects of circulating testosterone). This is why Yasmin is often chosen for women who experience bloating, breast tenderness or acne on other pills.
Dosering en toediening
Take one tablet at approximately the same time each day for 21 consecutive days, followed by a 7-day pill-free interval. A withdrawal bleed usually occurs during the pill-free week. Start the next 21-tablet pack on day 8 after the pill-free interval — on the same day of the week as the previous pack.
Starting Yasmin for the first time: ideally begin on day 1 of your menstrual period. If started on days 2–5, use additional contraception (condoms) for the first 7 days. If starting after a miscarriage or abortion, begin immediately. Postpartum, start no earlier than 21 days after delivery if not breastfeeding.
Missed Pill Protocol
- Missed by less than 12 hours: take the missed pill as soon as remembered, then continue the pack as usual — no loss of contraceptive effect.
- Missed by more than 12 hours, in week 1: take the missed pill immediately, continue the pack, and use condoms for the next 7 days. Emergency contraception may be indicated if unprotected sex occurred.
- Missed in week 2: take the missed pill, continue the pack. If three or more pills were taken correctly before the miss, no additional protection is needed.
- Missed in week 3: finish the active tablets, then skip the 7-day break and start the next pack immediately (no withdrawal bleed that cycle).
Side Effects of Yasmin
- Vaak voorkomend: breast tenderness; nausea (especially in the first weeks); headache; mild mood changes; irregular bleeding or spotting during the first 3 cycles.
- Minder vaak voorkomend: reduced libido; vaginal dryness or discharge change; weight fluctuation (typically less than older progestogens); acne flare in the first 2 months before improvement.
- Serious (rare but important to recognise): venous thromboembolism (DVT/PE) — symptoms include severe leg pain/swelling, sudden shortness of breath, chest pain; arterial thrombosis (stroke, heart attack) — severe headache, weakness, vision changes; severe hyperkalaemia in patients with kidney disease or on potassium-sparing medications; gallbladder disease; rare liver tumours with very long-term use.
Precautions and Warnings
- Smokers over age 35: combined oral contraceptives are generally contraindicated due to elevated cardiovascular risk.
- History of venous thromboembolism, arterial thrombosis, stroke: absolute contraindication.
- Migraine with aura: contraindicated — stroke risk.
- Uncontrolled hypertension: contraindicated.
- Active liver disease, liver tumours: contraindicated.
- Known or suspected pregnancy: contraindicated.
- Severe kidney disease: drospirenone can cause dangerous potassium retention — check renal function.
- Breast cancer (current or history): contraindicated.
- Obesity (BMI > 35): elevated thrombosis risk; discuss alternatives.
Geneesmiddelinteracties
Several medications reduce Yasmin’s contraceptive efficacy: enzyme-inducing antiepileptics (carbamazepine, phenytoin, phenobarbital), rifampicin/rifabutin, Sint-Janskruid, some HIV antiretrovirals (efavirenz, ritonavir). Use additional contraception or a non-hormonal method while on these drugs. Conversely, Yasmin may increase levels of: cyclosporine, prednisolone, theophylline. Watch for hyperkalaemia when combined with: ACE inhibitors, ARBs, potassium-sparing diuretics, NSAIDs at high dose, potassium supplements.
Opslag
Store below 25 °C in the original blister pack, protected from moisture. Keep out of reach of children. Do not freeze.
Veelgestelde vragen
How effective is Yasmin at preventing pregnancy?
With perfect use (no missed pills, correct timing, no interacting medications), Yasmin is over 99% effective. With typical use (accounting for occasional missed pills), real-world efficacy is around 91–93% — which translates to 7–9 pregnancies per 100 women in the first year of use. Strict pill-taking habits are the key to the perfect-use figure.
Can Yasmin help with acne?
Yes — drospirenone has mild anti-androgen activity, reducing the hormonal drive for sebum production. Clinical studies show meaningful improvement in moderate acne after 3–6 cycles, making Yasmin one of the preferred oral contraceptives for women who also want acne treatment.
What is the difference between Yasmin and Yaz?
Both contain drospirenone and ethinylestradiol. Yaz is a 24/4 regimen (24 active pills + 4 placebo) with a lower oestrogen dose (0.02 mg). Yasmin is a 21/7 regimen (21 active pills + 7-day break) with 0.03 mg oestrogen. Yaz has an additional FDA approval for PMDD; otherwise their effects are similar.
Is there a cancer risk with Yasmin?
Combined hormonal contraceptives slightly increase breast cancer risk (returning to baseline 10 years after stopping) and slightly increase cervical cancer risk with long use. They substantially reduce the risk of ovarian, endometrial and colorectal cancer. Net cancer effect is generally protective on a lifetime basis.
When will I know Yasmin is working?
If you start Yasmin on day 1 of your period, contraceptive protection is immediate. If you start on days 2–5, use condoms for the first 7 days. If starting at any other time in the cycle, use additional contraception for 7 days.
Can I take Yasmin continuously without the 7-day break?
Extended or continuous regimens (running multiple 21-tablet packs back-to-back without the break) are used by some women to reduce the frequency of withdrawal bleeds. Breakthrough spotting is common initially. Discuss with your doctor before adopting a continuous regimen.
What should I do if I vomit or have diarrhoea after taking Yasmin?
If you vomit within 3–4 hours of taking a pill, or have severe diarrhoea for more than 24 hours, pill absorption may have been incomplete. Treat the cycle as though you missed a pill: take another one from a spare pack, continue normally, and use backup contraception for 7 days.
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| Sterkte | 3 mg + 30 mcg |
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| Hoeveelheid | 21 Tablet/s, 42 Tablet/s, 63 Tablet/s, 126 Tablet/s |
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