Atenheal
Atenheal is atenolol 25/50/100 mg tablets — cardioselective beta-1 blocker. First-line for angina and atrial fibrillation rate control. Second-line for hypertension (LIFE trial showed inferior outcomes vs ARB-/CCB-based regimens). Hydrophilic — minimal CNS effects. Renally excreted — dose reduction needed in CKD.
✓ Lékařsky ověřeno Morgan Ellis — Pharmacy Researcher · 8 years experience Last reviewed: May 2026
⚡ Quick Answer — What is Atenheal?
Atenheal je 25 / 50 / 100 mg atenolol tablet from a WHO-GMP certified manufacturer — cardioselective (beta-1). Primary use is hypertension; also used for angina, arrhythmia control, post-myocardial-infarction secondary prevention, though atenolol-based hypertension therapy has inferior outcomes vs ACE-/ARB-/CCB-based regimens (LIFE trial) — now a second-line BP drug. Typical hypertension dose: 25-100 mg once daily. Contraindicated in asthma (relative for cardioselective agents; absolute for non-selective), severe bradycardia, second/third-degree heart block, acute decompensated heart failure, and phaeochromocytoma without prior alpha-blockade. Do NOT stop abruptly — taper over 1-2 weeks to avoid rebound tachycardia / angina / MI.
📦 Každá objednávka je pokryta naší Zárukou opětovného odeslání — pokud vaše zásilka nedorazí do 20 pracovních dnů, přeposíláme ji.
Proč objednávat z MedsBase
Naše generické léky pocházejí od výrobců certifikovaných WHO-GMP a jsou expedovány po celém světě v diskrétním, nenápadném balení – na vnější straně balíku není uveden název léku. Platby kartou jsou směrovány prostřednictvím regulovaného procesoru (popisky na výpisu zahrnují regulovaného procesora plateb kartou – nikdy “MedsBase” nebo název léku). Přijímáme také kryptoměny a bankovní převody SEPA. Každá objednávka je zajištěna naší politikou přeposlání.
What Is Atenheal?
Atenheal is an oral tablet containing atenolol 25 / 50 / 100 mg from a WHO-GMP certified manufacturer, supplied in 30-180 tablets. Atenolol is a cardioselective (beta-1). Introduced 1976 as one of the first cardioselective beta-blockers. Once a first-line antihypertensive, now generally relegated to a second-line agent — the LIFE trial (2002) and subsequent meta-analyses showed atenolol-based hypertension therapy produced inferior reductions in stroke, MI, and total mortality compared with ARB-, ACE-inhibitor-, and CCB-based regimens. Still widely used for angina, rate control, and arrhythmia suppression.
How Atenolol Lowers Blood Pressure
Beta-blockers reduce blood pressure through four mechanisms:
- Reduction of cardiac output — beta-1 blockade in the sinoatrial node reduces heart rate, and blockade in ventricular myocardium reduces contractility. Lower cardiac output = lower blood pressure.
- Renin-angiotensin suppression — beta-1 blockade in juxtaglomerular cells reduces renin release, lowering angiotensin II and aldosterone over 2-4 weeks. This accounts for much of the long-term BP effect.
- Central sympathetic reduction — lipophilic beta-blockers cross the blood-brain barrier and reduce central sympathetic outflow.
Beta-blockers are hydrophilic — minimal CNS penetration; one of the reasons it is poorly effective for migraine prevention (vs propranolol) but causes fewer CNS side effects (less fatigue, vivid dreams, depression). Plasma half-life of atenolol is 6-7 hours (renal excretion).
Approved and Evidence-Based Uses
- Hypertension (primary indication)
- Stable angina — remains first-line for symptomatic relief
- Atrial fibrillation rate control
- Supraventricular tachycardia
- Post-MI — evidence slightly weaker than metoprolol / carvedilol / bisoprolol
- Thyrotoxicosis — symptom control
- Situational anxiety — low-dose for performance anxiety (though propranolol is preferred for CNS penetration)
Atenheal Dosage
Adult hypertension dose: 25-100 mg once daily.
Start low, titrate upward over 2-4 weeks to target BP (typically <140/90 in uncomplicated hypertension; <130/80 in diabetes, chronic kidney disease, or established cardiovascular disease). Check resting pulse before each dose-increase — do not titrate if <55 bpm.
Monitorování:
- Resting pulse and BP at 2, 4, and 8 weeks after starting or dose change
- Baseline ECG if any cardiac history; periodic ECG if symptoms change
- Renal function (atenolol is renally excreted; dose reduction in eGFR <35)
Administration: swallow whole with water. Take at approximately the same time each day.
Discontinuation: NEVER stop abruptly. Taper over 1-2 weeks (reduce by 25-50% every 3-5 days). Abrupt discontinuation causes rebound tachycardia, worsened angina, and — in patients with coronary disease — can precipitate myocardial infarction. This is one of the most important safety points for beta-blockers.
Vedlejší účinky
Common (>5%):
- Fatigue, lethargy — often adapts over 2-4 weeks
- Cold hands and feet (peripheral vasoconstriction)
- Bradycardia (check pulse; stop if <50 bpm)
- Exercise intolerance — maximum heart rate is blunted by beta blockade
- Dizziness, postural hypotension
- Minimal CNS effects (hydrophilic)
- Reduced libido, erectile dysfunction (mostly at higher doses)
Méně časté: depression, reduced libido / erectile dysfunction, gastrointestinal upset, Raynaud-like cold intolerance, bronchospasm (more common with non-selective agents).
Important but uncommon:
- Masked hypoglycaemia in diabetics — beta-blockers blunt the tachycardia / tremor warning signs of low blood sugar. Monitor glucose more carefully; prefer nebivolol nebo bisoprolol in insulin-treated diabetes.
- Bronchospasm — can be severe in asthma / COPD. Absolute contraindication for non-selective agents; relative for cardioselective.
- Heart block or worsening heart failure — in susceptible patients. Start low, titrate slowly.
Contraindications & Cautions
- Severe asthma / severe COPD — relative contraindication (cardioselectivity is relative, not absolute)
- Second or third-degree atrioventricular block (without pacemaker)
- Sinus bradycardia <50 bpm
- Cardiogenic shock, decompensated heart failure requiring inotropes
- Severe peripheral arterial disease, Raynaud’s syndrome (relative)
- Phaeochromocytoma without prior alpha-blockade — paradoxical hypertensive crisis (never use a beta-blocker before alpha-blocker)
- Severe hepatic impairment (for extensively hepatic-metabolised agents: propranolol, metoprolol, carvedilol, labetalol)
- Severe renal impairment — dose adjustment needed for renal-excreted agents (atenolol, nadolol)
- Hypersensitivity to atenolol
Pregnancy: Category C; cross the placenta; small risk of intrauterine growth restriction, neonatal bradycardia, and hypoglycaemia. Use only if benefit clearly outweighs risk; labetalol is the pregnancy-preferred beta-blocker.
Breastfeeding: small amounts in breast milk; generally considered compatible with monitoring.
Interakce s léčivy
- Verapamil, diltiazem (non-dihydropyridine CCBs) — additive bradycardia, heart block, and negative inotropy; generally avoid combination. Dihydropyridine CCBs (amlodipine, nifedipine) are safer to combine with beta-blockers.
- Other beta-blockers — do not combine; additive bradycardia
- Clonidine — if stopping clonidine, stop the beta-blocker first (several days before) to avoid rebound hypertensive crisis
- Insulin and sulphonylureas — mask hypoglycaemia warning signs; monitor glucose closely
- NSAID — reduce the antihypertensive effect of beta-blockers; avoid chronic combination
- Alkohol — additive hypotension and CNS depression (particularly for lipophilic agents)
Beta-Blocker Class at a Glance
| Beta-blocker | Selectivity | Nejvhodnější pro |
|---|---|---|
| Propranolol (Inderal, Ciplar, Beloc) | Non-selective | Migraine, tremor, thyrotoxicosis, performance anxiety, HTN |
| Metoprolol | Cardioselective | Post-MI, HF-REF (succinate ER), angina, AF rate control |
| Carvedilol | Non-selective + α-1 | HF-REF (mortality evidence), post-MI |
| Bisoprolol | Highly cardioselective | HF-REF, HTN, angina, AF rate control |
| Nebivolol | Ultra-selective + NO | Elderly, metabolic syndrome, erectile dysfunction |
| Atenolol | Cardioselective (hydrophilic) | Angina, AF rate control (second-line for HTN) |
| Labetalol | Non-selective + α-1 | Pregnancy hypertension, hypertensive crisis |
Renal excretion means dose reduction is needed in renal impairment (halve the dose if eGFR 15-35; every-other-day dosing if eGFR <15). Hydrophilic profile means poor efficacy in migraine and essential tremor — prefer propranolol for those indications.
Skladování
Store Atenheal below 25°C. Keep out of reach of children — accidental paediatric beta-blocker ingestion can cause life-threatening bradycardia and hypoglycaemia.
Často kladené dotazy
How long does Atenheal take to lower blood pressure?
You should see some BP reduction within 1-2 days of starting; the full antihypertensive effect takes 2-4 weeks (driven by the gradual renin-angiotensin suppression, not the immediate heart-rate effect). Measure BP at home at the same time each day to track response.
Can I take Atenheal if I have asthma?
Atenolol is cardioselective, so it is relatively safer in asthma than non-selective agents. However, cardioselectivity is relative — at higher doses beta-2 blockade can still occur. In severe or brittle asthma, avoid all beta-blockers if possible. In mild asthma or COPD, use with monitoring and inhaler access.
Why should I never stop Atenheal abruptly?
Abrupt discontinuation causes rebound tachycardia and worsened angina within 24-48 hours, driven by up-regulation of beta receptors during chronic blockade. In patients with coronary artery disease, this can precipitate myocardial infarction or unstable angina. Always taper over 1-2 weeks when stopping.
Will Atenheal affect my exercise performance?
Yes — beta blockade blunts the heart-rate response to exercise, so your maximum pulse is lower and you fatigue faster at high intensities. For recreational exercise most people adapt; for competitive endurance athletes, beta-blockers can meaningfully impair performance and are banned in precision sports (shooting, archery — where they reduce physiological tremor).
Will Atenheal affect my blood sugar if I have diabetes?
Beta-blokátory mask the tachycardia / tremor / palpitation warning signs of hypoglycaemia, making low blood sugar harder to detect. They can also blunt the counter-regulatory glucose response. Monitor glucose more frequently on a beta-blocker, particularly if on insulin or sulphonylureas. Nebivolol a bisoprolol have the best metabolic profile.
Can I drink alcohol on Atenheal?
Moderate alcohol is generally acceptable but alcohol potentiates the hypotensive and CNS-depressant effects. Stand up slowly after drinking. Alcohol is also an independent BP-raiser; reducing intake can improve BP control independent of Atenheal.
Does Atenheal cause weight gain?
Older beta-blockers (propranolol, atenolol, metoprolol) are associated with modest weight gain (1-3 kg) and worsening of insulin sensitivity over time. Nebivolol and carvedilol are weight-neutral or slightly weight-favourable due to their vasodilator components. For patients with metabolic syndrome, nebivolol is the preferred beta-blocker when one is needed.
Is Atenheal safe in pregnancy?
Category C. Use only if benefit clearly outweighs risk. For antihypertensive use in pregnancy, labetalol is the preferred beta-blocker; methyldopa and nifedipine are the two other pregnancy-safe options.
Can I take Atenheal with other BP medications?
Yes — beta-blockers combine well with dihydropyridine calcium-channel blockers (amlodipine), ACE inhibitory (ramipril, lisinopril), ARBs (losartan, telmisartan, olmesartan), and thiazide diuretics (HCTZ). Avoid combination with non-dihydropyridine CCBs (verapamil, diltiazem) — additive bradycardia and heart-block risk.
Where can I buy Atenheal online?
You can buy Atenheal (atenolol 25 / 50 / 100 mg tablet, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.
Related Beta-Blockers & Antihypertensives
- Carloc — Carvedilol 3.125 mg (HF starter)
- Labebet — Labetalol 100 mg (pregnancy-safe)
- Metomac — Metoprolol 25 mg
- Provanol — Propranolol 10 mg
- Provanol SR — Propranolol 80 mg SR
- Topme XL — Metoprolol ER 100 mg
- Browse all High Blood Pressure Medications
Související alternativy
Další produkty v Chronická onemocnění které zákazníci také prohlížejí:
Další možnosti v léčbě vysokého krevního tlaku
Řazeno podle nedávného objemu objednávek na MedsBase — co si ostatní zákazníci v této kategorii vybírají.
| Quality | 28 Tablet/ks, 56 Tablet/ks, 84 Tablet/ks, 168 Tablet/ks |
|---|---|
| Síla | 25 mg, 50 mg, 100 mg |
Atenheal
Otázky a odpovědi
Atenheal
Související produkty
Hodnocení
Zatím zde nejsou žádná hodnocení