Lupimeb

📦 Každá objednávka je pokryta naší Zárukou opětovného odeslání — pokud vaše zásilka nedorazí do 20 pracovních dnů, přeposíláme ji.

Proč objednávat z MedsBase

Naše generické léky pocházejí od výrobců certifikovaných WHO-GMP a jsou expedovány po celém světě v diskrétním, nenápadném balení – na vnější straně balíku není uveden název léku. Platby kartou jsou směrovány prostřednictvím regulovaného procesoru (popisky na výpisu zahrnují regulovaného procesora plateb kartou – nikdy “MedsBase” nebo název léku). Přijímáme také kryptoměny a bankovní převody SEPA. Každá objednávka je zajištěna naší politikou přeposlání.

What is Lupimeb?

Lupimeb is mebendazole 100 mg chewable from Lupin. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.

Mechanismus účinku

Mebendazole binds β-tubulin in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores — the worm starves over 2–3 days. Mebendazole’s oral bioavailability is very low (< 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.

Lupimeb indications and dose

Tablets can be chewed, swallowed whole, or crushed and mixed with food.

Vedlejší účinky

• Časté: mild abdominal pain, transient diarrhoea, flatulence as worms pass
• Méně časté: headache, dizziness, mild rash
• Vzácné: reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)
• Very rare: Stevens-Johnson syndrome, toxic epidermal necrolysis

Interakce léků

• Cimetidin — raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites
• Phenytoin, carbamazepine, rifampicin — reduce mebendazole levels (CYP induction)
• Metronidazole — case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible

Kontraindikace

• Hypersensitivity to mebendazole or other benzimidazoles
• Children < 1 year
• First trimester of pregnancy
• Severe hepatic impairment

Skladování

Store Lupimeb below 30°C in the original blister, away from light and moisture.

Proč objednávat z MedsBase

Lupimeb is supplied from a výrobce certifikovaného WHO-GMP, balen diskrétně a expedován po celém světě. Každá objednávka je kryta naším Zárukou opětovného odeslání — nikdy neneseš náklady za ztracenou zásilku.

Často kladené dotazy

Can I just take one tablet?

For pinworm, yes — one 100 mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100 mg twice daily for 3 days.

Do I need to fast before Lupimeb?

No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.

Can my child chew Lupimeb?

Yes — the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).

How is mebendazole different from albendazole?

Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.

Will Lupimeb treat tapeworm?

Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.

How long until the worms are gone?

Adult worms are paralysed within 24–48 hours and pass in faeces over the following 3–5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1–2 weeks.

Is Lupimeb safe in pregnancy?

Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden — discuss with a clinician.

Can I drink alcohol with Lupimeb?

There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.

Does Lupimeb treat lice or scabies?

No. Mebendazole has no activity against ectoparasites — use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.

Should I retest after treatment?

For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2–4 weeks after treatment.

Patients seeking extended parasite coverage beyond Lupimeb (mebendazole 100 mg) may consider Wormentel (fenbendazole 222 / 500 mg) as a fenbendazole alternative in the same benzimidazole class but with a broader organism spectrum covering Giardia, tapeworm, and Trichinella.

Další antiparazitární léky

• Mebex (mebendazol 100 mg)
• Lupimeb (mebendazole 100 mg)
• ABD 400 (albendazol 400 mg)
• Nemocid (pyrantel pamoate)
• Iverheal (ivermectin)

Další možnosti v léčbě roupů

Řazeno podle nedávného objemu objednávek na MedsBase — co si ostatní zákazníci v této kategorii vybírají.

Iverheal

US$36.00 – US$699.00Fourchette de prix : US$36.00 à US$699.00

Prazinec

US$11.00 – US$56.00Fourchette de prix : US$11.00 à US$56.00

ABD 400 (Albendazol)

US$27.00 – US$122.00Fourchette de prix : US$27.00 à US$122.00

Ivimec

US$36.00 – US$575.00Fourchette de prix : US$36.00 à US$575.00