The MedsBase Heart & Blood Pressure parent catalogue groups all cardiovascular medications — antihypertensives across the major drug classes, anti-anginal nitrates, anti-arrhythmics, heart-failure agents, and pulmonary arterial hypertension specialty drugs. The detailed clinical breakdown by drug class with full molecule and brand listing is in our Medicatie tegen hoge bloeddruk sub-category — please browse there for selection guidance and dosing context. All products are supplied by WHO-GMP gecertificeerde fabrikanten.
Drug-class summary. ARBs (angiotensin-receptor blockers — losartan, valsartan, telmisartan, olmesartan, candesartan, irbesartan), ACE inhibitors (ramipril, lisinopril, enalapril, perindopril, captopril), beta-blockers (atenolol, metoprolol, bisoprolol, carvedilol, nebivolol, propranolol, labetalol, esmolol), calcium-channel blockers (amlodipine, nifedipine, felodipine, diltiazem, verapamil), diuretics (hydrochlorothiazide, indapamide, furosemide, torasemide, bumetanide, spironolactone, eplerenone, amiloride), alpha-blockers (prazosin, terazosin, doxazosin), centrally-acting agents (clonidine, alpha-methyldopa), nitrates (isosorbide mononitrate, isosorbide dinitrate, nitroglycerin sublingual / spray / patch), and specialty agents (ivabradine for HF, ambrisentan and riociguat for PAH, minoxidil for resistant HTN, sacubitril-valsartan for HFrEF).
Anti-thrombotic adjuncts. Aspirin 75–325 mg (Ecosprin), clopidogrel (Clodict, Plavix), warfarin (Warf, Waf-5), DOACs (Xarelto rivaroxaban, Eliquis apixaban) for primary and secondary cardiovascular prevention. See our Anti-Coagulants category.
Lipid-lowering co-treatment. Statins (atorvastatin, rosuvastatin, simvastatin, pitavastatin), fenofibrate, ezetimibe, and cholestyramine for cardiovascular risk reduction — see our Behandelingen voor hoog cholesterol category.
Hoe te kiezen. Modern ESC / NICE 2023 first-line for hypertension: ARB or ACE inhibitor (under 55, non-Black) OR calcium-channel blocker (over 55 or Black). Step-up to dual therapy (ARB/ACEi + CCB), then triple (add thiazide / thiazide-like diuretic), then quadruple (add spironolactone if K+ < 4.5). Target BP < 140/90 (130/80 in diabetes / CKD / high CVD risk). Heart-failure with reduced ejection fraction (HFrEF) — sacubitril-valsartan (or ARB/ACEi) + beta-blocker + MRA + SGLT-2 inhibitor (the four pillars). Coronary artery disease — beta-blocker + statin + antiplatelet + ACEi/ARB if HTN or LV dysfunction.
Belangrijk. Cardiovascular medications work best when taken consistently — please keep your primary-care team and cardiologist informed. Sudden discontinuation of beta-blockers or clonidine causes rebound hypertension / angina / arrhythmia — always taper. ACEi / ARB combinations are no longer recommended (ON-TARGET trial). Pregnancy: ACE inhibitors and ARBs are absolutely contraindicated; methyldopa, labetalol, nifedipine are first-line for pregnancy hypertension. Severe symptomatic hypotension, syncope, oedema, breathlessness, palpitations, or chest pain warrants prompt medical assessment.
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