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Nebracin Eye Drop

Nebracin (tobramycin 0.3%) — aminoglycoside eye drop for Gram-negative bacterial conjunctivitis. Hourly dosing in severe ulcers; corneal-toxicity caution beyond 7 days.

SKU: Nebracin Eye Drop Categorie: , ,

Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring  · Laatst beoordeeld: mei 2026

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⚡ Quick Answer — What is Nebracin Eye Drop?

Nebracin Eye Drop is Tobramycin 0.3% ophthalmic solution, an aminoglycoside antibiotic for bacterial conjunctivitis, blepharitis, and external eye infections. Strong Pseudomonas and Staphylococcus aureus coverage. Used 4–6 times daily.

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📦 Elke bestelling is gedekt door onze Reshipment Assurance Policy — als uw pakket niet binnen 20 werkdagen arriveert, sturen wij het opnieuw.

Waarom bestellen bij MedsBase

Nebracin Eye Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy — als het niet is aangekomen na 20 werkdagen, sturen wij het opnieuw zonder extra kosten. Ondersteund door meer dan 1.400 geverifieerde klantbeoordelingen.

What is Nebracin Eye Drop?

Nebracin Eye Drop is manufactured by FDC and contains Tobramycin 0.3% as a sterile ophthalmic solution. Aminoglycosides are bactericidal antibiotics that have been used in ophthalmology for decades — particularly valued for Gram-negative coverage (including Pseudomonas) and Staphylococcus aureus.

Hoe het werkt

Tobramycin binds the 30S ribosomal subunit in bacteria, causing misreading of mRNA and the production of dysfunctional proteins. The bacterium synthesises faulty membrane proteins that eventually compromise membrane integrity, leading to cell lysis. The mechanism is bactericidal and concentration-dependent.

Indicaties

  • Bacterial conjunctivitis — confirmed or strongly suspected
  • Bacterial blepharitis
  • Hordeolum (stye) / chalazion with bacterial component
  • Bacterial keratitis — particularly Pseudomonas; under ophthalmologist supervision
  • Post-operative prophylaxis after cataract or corneal surgery

Dosering

IndicatieDosering
Bacterial conjunctivitis (mild-moderate)1–2 drops in affected eye(s) every 4 hours for 7 days
Severe infection2 drops every 1 hour until improvement, then taper
Corneal ulcer (specialist)Hourly day and night for 24–48 hours, then taper based on response
Corneal toxicity with prolonged use. Aminoglycosides can cause superficial punctate keratopathy and delayed corneal epithelial healing with prolonged use (> 14 days). They are excellent for short courses but inappropriate for chronic prophylaxis. Topical absorption is minimal — there is no risk of the systemic ototoxicity or nephrotoxicity seen with intravenous aminoglycosides.

Bijwerkingen

Lokaal: stinging, burning, conjunctival hyperaemia, eyelid itching or swelling, hypersensitivity reactions (more common with neomycin, less with tobramycin/gentamicin), punctate keratitis with prolonged use.

Systemisch: negligible from topical use. Theoretical risks of ototoxicity and nephrotoxicity apply only to systemic dosing.

Waarschuwingen & Contra-indicaties

  • Hypersensitivity to aminoglycosides
  • Viral, fungal, or mycobacterial keratitis
  • Acanthamoeba keratitis (contact-lens users)
  • Avoid prolonged use beyond 14 days
  • Pregnancy / breastfeeding — topical absorption minimal, generally considered acceptable

Opslag

Bewaren bij 15–25°C. Na eerste opening 28 dagen houdbaar.

Veelgestelde vragen

When is Nebracin Eye Drop used?

Bacterial conjunctivitis, blepharitis, hordeolum, and pre/post-operative prophylaxis. Aminoglycosides have particularly strong Gram-negative coverage including Pseudomonas — important for contact-lens-associated keratitis.

How long should I use Nebracin Eye Drop?

5–7 days for conjunctivitis. Avoid courses beyond 14 days because of corneal toxicity (delayed epithelial healing).

What is the difference between solution and ointment?

Solutions are dosed 4–6 times daily and don’t blur vision. Ointments stay in the eye longer (dosed 2–3 times daily) but blur vision for 5–10 minutes after application — best used at bedtime.

Can I wear contact lenses?

No — stop lenses during treatment and for 24 hours after symptoms resolve. Contact-lens-associated keratitis specifically requires lens cessation.

What is corneal toxicity?

Long-term aminoglycoside use can damage corneal epithelial cells and slow healing. This is why courses should be limited to 7–14 days. Pseudomonas resistance also develops with prolonged exposure.

Is Nebracin Eye Drop safe in pregnancy?

Topical absorption is minimal. Generally considered acceptable when clearly indicated. Discuss with your prescriber.

Can Nebracin Eye Drop cause hearing loss?

Topical aminoglycosides do not reach high enough systemic levels to cause ototoxicity. The systemic ototoxicity warning applies only to IV gentamicin/tobramycin used for serious infections.

What if I have a hypersensitivity reaction?

Stop the drop. Symptoms include increasing redness, swelling of the lid skin, severe itching. Switch to a non-aminoglycoside antibiotic (fluoroquinolone, chloramphenicol).

What if symptoms don't improve in 48 hours?

The infection may not be susceptible, may be viral or fungal, or there may be a foreign body or other cause. Urgent ophthalmology review is appropriate.

Can Nebracin Eye Drop be used in young children?

Yes — generally well tolerated from infancy. Always under guidance for very young infants.

Andere oogzorgmedicijnen

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Medische Disclaimer

De informatie op deze pagina is alleen voor educatieve doeleinden en is geen vervanging voor medisch advies van een gekwalificeerde oogarts of optometrist. Oogaandoeningen kunnen snel een bedreiging vormen voor het gezichtsvermogen — plotseling verlies van gezichtsvermogen, hevige pijn of trauma is een oogheelkundig spoedgeval. Raadpleeg altijd een oogzorgprofessional voordat u een behandeling start, stopt of wijzigt.

Meer opties in oogzorg

Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.

Sterkte

0.3% (5 ml) Eye Drop

Hoeveelheid

1 Oogdruppel, 3 Oogdruppels, 6 Oogdruppels

Farmaceutische vorm

Oogdruppel/s

Fabrikant

Sunways India

Behandeling

Oogzorg

Generiek merk

Tobramycin

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