Cifran OZ

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Productoverzicht

Cifran OZ is a medication containing the active ingredients Ciprofloxacin (500mg) and Ornidazole (500mg) in tablet form. It is a broad-spectrum antibiotic and antiprotozoal combination used to treat various bacterial and parasitic infections. Cifran OZ works by inhibiting the growth and replication of bacteria and certain parasites, thereby helping the body’s immune system to eliminate the infection.

Toepassingen

Cifran OZ is prescribed for the treatment of various bacterial infections, including urinary tract infections, respiratory tract infections, gastrointestinal infections, skin and soft tissue infections, and sexually transmitted infections. Additionally, it is effective against certain protozoal infections such as amoebiasis and giardiasis. Cifran OZ is often recommended when the infection is suspected to be caused by susceptible organisms.

Hoe te gebruiken

Cifran OZ tablets should be taken orally with a full glass of water, preferably with meals to reduce the risk of gastrointestinal upset. Swallow the tablets whole; do not crush, chew, or break them before swallowing. It is essential to complete the full course of treatment as prescribed by your healthcare provider, even if symptoms improve before the course is finished. Skipping doses or stopping the medication prematurely may result in incomplete treatment and the risk of recurrence or resistance.

Werking

Cifran OZ combines two active ingredients, Ciprofloxacin and Ornidazole, each targeting different types of pathogens. Ciprofloxacin belongs to the class of antibiotics known as fluoroquinolones, which inhibit bacterial DNA gyrase and topoisomerase IV enzymes, essential for bacterial DNA replication, transcription, repair, and recombination. Ornidazole is an antiprotozoal agent that interferes with the DNA structure of protozoa, leading to their death. Together, these ingredients provide broad-spectrum antimicrobial activity against bacteria and certain parasites.

Dosering en toediening

The dosage of Cifran OZ tablets varies depending on the type and severity of the infection, as well as the patient’s age, weight, and renal function. It is typically taken twice daily for 5 to 14 days, as directed by your healthcare provider. Always follow your doctor’s instructions and complete the full course of treatment, even if symptoms improve before the medication is finished.

Voordelen

• Effective treatment for bacterial and protozoal infections
• Broad-spectrum antimicrobial coverage
• Convenient oral administration with tablets
• Rapid onset of action
• Well-tolerated with minimal side effects

Veelvoorkomende bijwerkingen

Common side effects of Cifran OZ may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and taste disturbances. These side effects are usually mild and temporary, resolving with continued use or upon discontinuation of the medication. However, if any side effects persist or become severe, consult your healthcare provider for further guidance.

Waarschuwingen

Cifran OZ should be used with caution in patients with a history of hypersensitivity to fluoroquinolones, nitroimidazoles, or any other components of the formulation. It may cause tendon rupture, especially in older adults, and should be discontinued if tendon pain or inflammation occurs. Cifran OZ may also increase the risk of Clostridium difficile-associated diarrhea and peripheral neuropathy. Use in pregnancy and breastfeeding women should be carefully considered, and only if the potential benefits outweigh the risks.

Bewaarinformatie

Store Cifran OZ tablets at room temperature, away from moisture, heat, and direct sunlight. Keep the medication out of reach of children and pets. Do not use expired medication, and dispose of any unused or expired tablets properly according to local regulations.

Disclaimer:

Onze enige intentie is ervoor te zorgen dat consumenten informatie krijgen die deskundig beoordeeld, nauwkeurig en betrouwbaar is. De informatie hier mag echter NIET worden gebruikt als vervanging voor het advies van een gekwalificeerde arts. De verstrekte informatie is uitsluitend bedoeld voor informatieve doeleinden. Dit omvat mogelijk niet alle mogelijke bijwerkingen, geneesmiddelinteracties, waarschuwingen of meldingen. Raadpleeg uw arts en bespreek al uw vragen met betrekking tot een ziekte of medicijn. Wij willen de arts-patiëntrelatie ondersteunen, niet vervangen.

Veelgestelde vragen

Why is Cifran OZ a fixed-dose combination?

Cifran OZ combines a fluoroquinolone (broad gram-negative + atypical cover) with a nitroimidazole (anaerobic cover) to treat mixed aerobic/anaerobic infections in a single tablet — most commonly intra-abdominal, pelvic, gynaecological, dental, and infected diabetic-foot infections.

Can I drink alcohol while taking Cifran OZ?

No. The nitroimidazole component (ornidazole or metronidazole) can produce a disulfiram-like reaction with alcohol — flushing, nausea, vomiting, palpitations, and headache. Avoid all alcohol during the course AND for 48 hours after the last dose, including mouthwash and cough syrup.

Should I separate Cifran OZ from antacids and supplements?

Yes. The fluoroquinolone fraction binds aluminium/magnesium antacids, sucralfate, iron, zinc, calcium, and dairy. Take Cifran OZ at least 2 hours before or 6 hours after any of these.

Is Cifran OZ safe in pregnancy?

Cifran OZ is generally avoided in pregnancy. The fluoroquinolone fraction has a theoretical arthropathy signal in the foetus, and metronidazole is avoided in the first trimester. Specialist supervision required for any pregnancy use.

Wat zijn de meest voorkomende bijwerkingen?

Nausea, metallic taste (from the nitroimidazole), abdominal discomfort, dizziness, and a transient skin rash. Rarer but serious: tendon pain (stop and seek review), seizures, peripheral neuropathy with prolonged use of either component, and Clostridioides difficile colitis.

How long is a typical course of Cifran OZ?

5–7 days is typical for routine intra-abdominal or gynaecological infection. Severe, complicated, or specialist-managed infections may run longer. Complete the prescribed course even if symptoms resolve early.

Other Anti-Infective Medications

• Cipmox — amoxicillin
• Clavam Dry Syrup — amoxicillin + clavulanate
• Cetil — cefuroxime
• Cefoprox — cefpodoxime
• Taxim-O DT — cefixime

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