⚡ Quick Answer — What is Kidpred Syrup?
Kidpred Syrup is an oral syrup from Cipla containing prednisolone — a synthetic glucocorticoid with strong anti-inflammatory and immunosuppressive activity. Supplied in a 60 mL bottle of paediatric prednisolone oral syrup; the liquid formulation makes accurate weight-based dosing straightforward in children too young to swallow tablets reliably. Used for short courses in acute asthma exacerbation (1–2 mg/kg/day for 3–5 days), croup (1 mg/kg single oral dose, often combined with nebulised epinephrine), severe allergic reactions and angioedema, eczema flares, and longer courses in nephrotic syndrome (60 mg/m²/day in induction, then alternate-day taper) and other paediatric autoimmune disease. Standard paediatric dose: 1–2 mg/kg/day in 1–2 divided doses, capped at typical adult equivalents. Always weigh the child before each course; doses must be calculated from current weight. Short courses (< 5–7 days) need no taper; longer courses need supervised taper to prevent adrenal crisis. Repeated or prolonged courses can suppress linear growth — height and weight monitoring at every prescriber review.
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What Is Kidpred Syrup?
Kidpred Syrup is an oral syrup manufactured by Cipla containing prednisolone, a medium-potency synthetic glucocorticoid. The liquid formulation is the standard paediatric presentation: it allows precise milligram dosing for small children and infants, and is much easier to administer than crushed tablets to babies and toddlers.
Kidpred Syrup is Cipla's standard paediatric prednisolone oral liquid — designed for children too young to swallow tablets reliably and where exact weight-based dosing matters. Comes in a 60 mL bottle with a measuring device for accurate dosing. Always confirm the per-mL strength stated on the bottle label before measuring (Indian paediatric prednisolone syrups are typically 5 mg/5 mL or 15 mg/5 mL; the same dose volume gives a 3× different drug dose between these two concentrations). Prednisolone has strong anti-inflammatory and immunosuppressive effects across almost every tissue. In paediatric practice it is most commonly used for short courses in acute asthma and croup, single-dose treatment of croup, longer courses in nephrotic syndrome, and selected autoimmune and allergic conditions.
How Does Kidpred Syrup Work?
Prednisolone enters cells, binds the intracellular glucocorticoid receptor, and the receptor-drug complex translocates to the nucleus where it alters transcription of hundreds of inflammation-related genes. The result is broad suppression of pro-inflammatory cytokines (IL-1, IL-6, TNF-α), inhibition of phospholipase A&sub2; via lipocortin (cutting off prostaglandin and leukotriene production upstream), reduced capillary permeability, and suppressed lymphocyte and eosinophil function.
Plasma half-life: 2–3 hours; biological (anti-inflammatory) half-life: 12–36 hours. Once-daily morning dosing gives effective day-long anti-inflammatory cover for most paediatric indications, while minimising HPA-axis suppression compared with split or evening dosing.
Onset of clinical effect in acute paediatric inflammatory conditions: noticeable improvement in croup or asthma within 2–4 hours of the first dose; peak anti-inflammatory effect at 4–8 hours. Effect persists for 24–36 hours after dosing.
Toepassingen en Indicaties
Kidpred Syrup is used across a wide range of paediatric inflammatory and autoimmune conditions:
- Acute asthma exacerbation — short course of 3–5 days, no taper needed. Single most common use in Indian paediatric practice.
- Croup (laryngotracheobronchitis) — single oral 1 mg/kg dose at presentation, often combined with nebulised epinephrine. Reduces hospital admission and respiratory deterioration.
- Severe allergic reactions, urticaria, angioedema — short course of 3–5 days at 1–2 mg/kg/day.
- Severe atopic dermatitis (eczema) flare — short course; topicals first.
- Nephrotic syndrome (typically minimal change disease in children) — standard induction is 60 mg/m²/day for 4–6 weeks, then alternate-day 40 mg/m² for 4–6 weeks, with relapses managed by similar protocols.
- Juvenile idiopathic arthritis flare — bridging therapy during DMARD initiation.
- Inflammatory bowel disease flare — short courses for moderate-severe Crohn's or ulcerative colitis flare.
- Idiopathic thrombocytopenic purpura (ITP), autoimmune haemolytic anaemia
- Acute Kawasaki disease (adjunct to IVIG in some protocols)
- Severe viral wheeze in young children — selected cases; evidence less robust than for true asthma.
- Acute spinal cord injury, severe head injury, severe sepsis — specialist intensive care indications.
Kidpred Syrup is niet appropriate for: simple viral upper respiratory infection, undiagnosed wheeze in infants < 12 months (high risk of viral bronchiolitis where steroids are unhelpful or harmful), or routine eczema management (topical steroids first).
Kidpred Syrup Dosage and How to Give to a Child
Paediatric dosing is weight-based; always weigh the child before each course and re-weigh for any course longer than 1 month. The strength of prednisolone in syrup varies between manufacturers (commonly 5 mg/5 mL or 15 mg/5 mL) — always confirm the per-mL strength on the bottle label before measuring the dose.
Standard paediatric doses by indication
| Indicatie | Dosering | Duur |
|---|---|---|
| Acute asthma exacerbation | 1–2 mg/kg/day (max 40–60 mg/day) once daily morning | 3–5 days, no taper |
| Croup | 1–2 mg/kg as a single oral dose (max 60 mg) | Single dose; repeat 1–2 times in severe cases |
| Severe allergic reaction / angioedema | 1–2 mg/kg/day once daily | 3–5 dagen |
| Severe eczema flare | 0.5–1 mg/kg/day | 5–7 days; topical steroid maintenance afterward |
| Nephrotic syndrome induction | 60 mg/m²/day (max 60–80 mg/day) | 4–6 weeks, then alternate-day taper for 4–6 weeks |
| JIA flare bridging | 0.5–1 mg/kg/day | Until DMARD takes effect; usually 2–6 weeks then taper |
| ITP / AIHA | 2–4 mg/kg/day | Until response, then taper over weeks |
How to Measure and Administer Kidpred Syrup Properly
- Weigh the child first. Always calculate the dose from the actual current weight, not memorised from previous courses. Children grow.
- Confirm the strength on the bottle label. If 15 mg/5 mL, then 5 mL = 15 mg; if 5 mg/5 mL, then 5 mL = 5 mg. The same dose volume gives a 3× different drug dose between these two products.
- Use the supplied calibrated oral syringe or measuring cup, not a household teaspoon. Household teaspoons range from 2.5 to 7.5 mL; using one introduces a 3-fold dosing error.
- Give the dose in the morning (between waking and breakfast). Morning dosing mimics natural cortisol rhythm and minimises HPA suppression and insomnia.
- Give with food — reduces gastric irritation and the often-unpleasant taste. Mix with a small amount of fruit juice (apple, mango) or a spoon of yoghurt if needed; do not mix into the full bottle of milk because the child may not finish it.
- If the child vomits within 30 minutes of the dose, repeat the full dose. If vomiting after 30 minutes but within 2 hours, repeat half the dose. If after 2 hours, do not repeat.
- Never miss a dose during an acute course. If a dose is missed, give it as soon as remembered, then return to the normal schedule. Do not double up.
- Never stop suddenly after a course longer than 5–7 days. Tapering is needed to prevent adrenal crisis. Follow the prescriber's taper plan exactly.
- Track height and weight at every paediatrician visit during prolonged courses — growth suppression is the single most important paediatric-specific concern.
- Tell every healthcare provider — school nurse, dentist, ED clinician — that the child is on Kidpred Syrup.
Stopping Kidpred Syrup — Why Tapering Matters in Children
Children on prolonged steroid courses face the same HPA-axis suppression as adults, and abrupt withdrawal can precipitate adrenal crisis. The risk is highest after long courses (more than 2–3 weeks at > 1 mg/kg/day) but can occur after even shorter courses at high dose.
- Courses shorter than 5–7 days at 1–2 mg/kg/day — can usually be stopped without a taper.
- Courses 1–3 weeks at 1–2 mg/kg/day — reduce by 0.25–0.5 mg/kg every 3–5 days until off, or follow the prescriber's specific plan.
- Courses longer than 3 weeks at 1–2 mg/kg/day, or any nephrotic-syndrome regimen — specialist-supervised taper, often over weeks to months, sometimes via alternate-day dosing.
- Sick-day cover — a child on prolonged steroid (including the recent few weeks after stopping a long course) needs additional steroid cover during fever, vomiting, severe illness or surgery, just like adults. Discuss explicit sick-day rules with the prescriber.
- Withdrawal symptoms — if the child becomes lethargic, has poor appetite, joint pain or feels generally unwell during the taper, step back up one level and taper more slowly.
Side Effects of Kidpred Syrup in Children
Side effects of paediatric prednisolone closely mirror adult use but with paediatric-specific concerns about growth and behaviour.
Short-term (days to weeks), common:
- Increased appetite, weight gain
- Mood and behaviour change — irritability, agitation, hyperactivity, occasional brief psychosis at high doses (often called “steroid rage” by parents)
- Insomnia, vivid dreams
- Heartburn, dyspepsia
- Acne flare in older children and adolescents
- Raised blood sugar (only relevant in pre-existing or newly-detected diabetes)
Medium-term (weeks to months):
- Cushingoid appearance — round face, central weight gain, buffalo hump
- Skin thinning, easy bruising, striae
- Increased susceptibility to bacterial, viral and fungal infection
- Cataract (especially with prolonged daily use)
- Raised intraocular pressure
Long-term (months to years):
- Linear growth suppression — the single most paediatric-specific concern. Cumulative effect; partially recoverable after stopping the steroid in younger children, less so in older children near puberty.
- Osteoporosis and fracture risk
- Persistent diabetes
- HPA-axis suppression
- Severe immunosuppression with opportunistic infection (severe varicella, measles, Pneumocystis, TB reactivation)
Rare but serious — seek urgent paediatric review:
- Severe varicella in a non-immune child on steroid — can be fatal; needs IV aciclovir and specialist input. Pre-treatment varicella status should be confirmed before any prolonged course.
- Severe psychiatric reaction, hallucination, severe agitation
- Severe infection, especially bacterial pneumonia, septic arthritis, meningitis with masked symptoms
- Adrenal crisis during/after withdrawal
- Sudden vision changes
- Severe abdominal pain (possible GI ulceration)
Waarschuwingen en voorzorgsmaatregelen
- Active or untreated infection — steroids mask signs of infection and worsen outcomes. Especially relevant in children with possible bacterial meningitis (where dexamethasone is given pre-antibiotic for specific indications) or septic arthritis.
- Varicella status — confirm chickenpox immunity (history of infection or vaccination) before any prolonged course. Severe varicella in a non-immune child on steroid is a medical emergency.
- Recent live vaccine exposure — defer high-dose courses if possible. Live vaccines (MMR, varicella, BCG, oral polio in some countries, yellow fever) contraindicated at ≥ 2 mg/kg/day for more than 14 days, and for 3 months after stopping.
- Diabetes — paediatric type-1 diabetes needs significant insulin up-titration during steroid courses.
- Tuberculosis exposure — in TB-endemic regions including India, screen for latent TB before any prolonged course.
- Behavioural and psychiatric history — warn parents about behaviour change. Most resolves at the end of the course.
- Premature infants and neonates — steroid use is associated with neurodevelopmental concern; specialist neonatology supervision only.
- Long-term courses — growth monitoring at every visit, consider DEXA scan for any course longer than 6 months at significant dose.
- Levende vaccins — planned and travel vaccinations should be given before any prolonged course where possible.
Contraindications — Children Who Should NOT Receive Kidpred Syrup
- Known hypersensitivity to prednisolone or any syrup excipient (including the alcohol or preservative content of some formulations — check the label)
- Systemic fungal infection (unless covered by antifungal therapy)
- Untreated active infection without appropriate antimicrobial cover
- Recent live vaccine at immunosuppressive doses
- Cerebral malaria (corticosteroids worsen outcome)
- Acute viral bronchiolitis in infants under 12 months — steroid is not effective and may be harmful
Geneesmiddelinteracties
| Combineren met | Effect | Wat te doen |
|---|---|---|
| NSAID's (ibuprofen, diclofenac) | Major additive GI ulceration risk in children just as in adults | Avoid combination if possible; co-prescribe a paediatric PPI for any sustained NSAID + steroid use. |
| Diabetes medications | Steroids raise blood glucose | Significant insulin up-titration during course in type-1 diabetes. |
| Strong CYP3A4 inhibitors (clarithromycin, ketoconazole, ritonavir) | Raise prednisolone levels | Watch for amplified Cushingoid effects; consider lower dose. |
| Sterke CYP3A4-induceerders (rifampicine, fenytoïne, carbamazepine) | Lower prednisolone levels | May need higher steroid dose in children on these long-term medications. |
| Levende vaccins | Risk of disseminated vaccine-strain infection in immunosuppressed child | Contraindicated at ≥ 2 mg/kg/day for > 14 days, and for 3 months after. |
| Beta-2 agonists (salbutamol, levosalbutamol, terbutaline) | Additive hypokalaemia — relevant in severe asthma exacerbation requiring high-dose nebulised beta-agonist + IV/oral steroid | Check potassium in severe acute asthma; supplement as needed. |
| Other immunosuppressants (methotrexate, ciclosporin, biologics) | Additive infection risk | Combinations are common in juvenile arthritis or nephrotic syndrome — specialist supervision. |
Bewaaradvies
- Bewaren bij kamertemperatuur, below 25°C, protected from light. Some formulations may require refrigeration after opening — check the bottle label.
- Keep the bottle tightly closed when not in use.
- Use within the labelled in-use period after opening (typically 4–6 weeks; check the label).
- Do not use if the syrup has changed colour, become cloudy, or smells off.
- Buiten bereik van kinderen houden — the sweet flavouring of paediatric syrups makes accidental over-dose by curious siblings a real risk.
- Do not use after the expiry date on the bottle.
- Return unused syrup to a pharmacy for disposal — do not pour down the sink.
Gerelateerde alternatieven op MedsBase
Other medications used in anti-inflammatory and autoimmune care stocked alongside this product:
- Barinat (baricitinib 2 / 4 mg) — JAK1/2 inhibitor for RA
- Tofe (tofacitinib 5 mg) — JAK1/3 inhibitor for RA, UC, PsA
- Azoran (azathioprine 50 mg) — classic immunosuppressant DMARD
- Lefuheal (leflunomide) — oral DMARD for rheumatoid arthritis
- Conimune ME (cyclosporine) — calcineurin inhibitor
- Wysolone (prednisolone 5 / 10 / 20 mg) — oral corticosteroid
- Medrol (methylprednisolone 4 / 8 / 16 mg) — oral corticosteroid
- Predniheal (prednisolone) — oral corticosteroid
- Hisone (hydrocortisone) — physiologic replacement steroid
- Budez CR (budesonide) — gut-targeted corticosteroid for Crohn's
- Kenacort (triamcinolone) — systemic corticosteroid
Explore the full Ontstekingsremmende & Auto-immuunzorg category.
Veelgestelde vragen
How do I measure Kidpred Syrup accurately?
Use the calibrated oral syringe or measuring cup that comes with the bottle, NOT a household teaspoon. Household teaspoons range from 2.5 to 7.5 mL, which means using one introduces a 3-fold dose error. If the supplied measure is lost, ask the pharmacy for a replacement oral syringe or buy one separately. Always read the per-mL strength on the bottle label and calculate the dose volume before measuring.
Will Kidpred Syrup stunt my child's growth?
A short course of 3–5 days for asthma or croup has no detectable effect on long-term growth. Repeated short courses (e.g. multiple asthma courses per year) cause a small, usually reversible reduction in growth velocity. Prolonged daily courses (months or years, e.g. for nephrotic syndrome or severe juvenile arthritis) cause cumulative growth suppression that may be partially recoverable after stopping in younger children, less so as the child approaches puberty. Pediatricians monitor height, weight and growth velocity at every visit during prolonged courses, and will switch to alternate-day dosing or steroid-sparing agents when possible to minimise the impact.
My child becomes really hyperactive and irritable on Kidpred Syrup — is this normal?
Yes, this is one of the most common parent complaints. Behaviour change — irritability, agitation, hyperactivity, sleep disturbance, occasionally what feels like a different child — is very common in paediatric steroid courses. It usually resolves within a few days of finishing the course. Mitigations: morning-only dosing, consistent bedtime routine, reduced screen time, more outdoor time. Severe behaviour change (hallucination, frank psychosis, aggression that is dangerous) is uncommon but warrants prescriber review and possible dose reduction or early discontinuation.
My child vomited the dose — should I give it again?
If vomiting occurs within 30 minutes of the dose, give the full dose again. If vomiting between 30 minutes and 2 hours, give half the dose again. If vomiting after 2 hours, the dose has been absorbed — do not repeat. If the child is vomiting repeatedly and cannot keep oral steroid down, contact the prescriber — they may switch to IV/IM administration in hospital, particularly if the underlying disease (acute asthma, severe allergic reaction, nephrotic syndrome flare) needs continued steroid cover.
Can my child go to school on Kidpred Syrup?
Yes, in most cases. Tell the school nurse and class teacher that the child is on a steroid course. Two specific concerns: (1) severe varicella exposure — if there is a chickenpox case in the class and your child is not immune (no history of chickenpox or vaccination), notify the prescriber immediately for possible varicella zoster immunoglobulin (VZIG); (2) severe measles exposure — same principle. Avoid sick contacts where possible; otherwise normal school attendance is fine.
Can my child have routine vaccinations on Kidpred Syrup?
Inactivated vaccines — flu (injection, not nasal), pneumococcal, COVID-19, hepatitis A/B, HPV, meningococcal — are safe and recommended at any steroid dose. Levende vaccins — MMR, varicella, BCG, oral polio (where used), yellow fever, live nasal flu, live Zostavax — are contraindicated at ≥ 2 mg/kg/day prednisolone for more than 14 days, and for 3 months after stopping. Plan all live vaccinations before starting any prolonged course where possible.
Why give the dose in the morning?
The body's own cortisol peaks between 6 and 9 a.m. Morning dosing of prednisolone mimics this natural pattern, suppresses the HPA axis less than evening dosing, and reduces insomnia. For very long-term paediatric use (e.g. nephrotic syndrome maintenance), alternate-day morning dosing is sometimes preferred to allow some HPA recovery on off-days while maintaining disease control.
My child has been on Kidpred Syrup for a few weeks and now has a fever — what do I do?
Tell the prescriber the same day. A child on prolonged steroid has a blunted ability to mount fever and immune response, so any fever signals possible serious infection. Common things to consider: chest infection, urinary tract infection, skin infection, atypical pneumonia, varicella exposure if non-immune. The child may also need a temporary INCREASE in steroid dose (sick-day cover) rather than a decrease — ask the prescriber for explicit sick-day rules at the start of any course longer than 2–3 weeks.
When can I stop Kidpred Syrup?
For short courses (3–7 days for asthma, croup, allergy), stop at the end of the planned course — no taper. For courses longer than 5–7 days, follow the prescriber's written taper plan. Never stop a long course suddenly. If you forgot to ask about tapering and the bottle is finishing, contact the prescriber for a step-down plan rather than stopping abruptly. Tapering is your safety net against adrenal crisis.
Waarom bestellen bij MedsBase
Kidpred Syrup is supplied through a WHO-GMP certified manufacturer with full COA documentation. We ship worldwide in plain, discreet packaging, and every order is covered by our Reshipment Assurance Policy. Uw betalingsbeschrijving bij betaling per kaart toont de gereguleerde betalingsverwerker (een gereguleerde kaartbetalingverwerker), nooit “MedsBase” of een medicijnnaam.
Other Anti-Inflammatory & Autoimmune Medications
If Kidpred Syrup does not suit your situation, the following options are available in this category:
- Wysolone (Prednisolone 5/10/20 mg, Wyeth) — adult tablet equivalent
- Predniheal (Prednisolone 5/10/20/40 mg, Healing Pharma) — full strength range
- Medrol (Methylprednisolone 4/8/16 mg, Pfizer) — alternative oral steroid
- Kenacort (Triamcinolone 4 mg, Abbott) — fluorinated, no fluid retention
- Betnesol Tab (Betamethasone 0.5 mg) — long-acting steroid



























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