Reactin
✅ Pain relief
✅ Anti-inflammatory properties
✅ Reduces swelling
✅ Eases joint discomfort
✅ Manages arthritis symptoms
Reactin contains Diclofenac.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Reactin?
Reactin is een diclofenac 50 mg tablet (immediate release), a potent non-selective NSAID widely used for acute and chronic pain and inflammation. Typical adult dose is 50 mg three times daily with food (maximum 150 mg/day). Reactin is indicated for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, musculoskeletal injury, post-operative pain, dysmenorrhoea, and renal/biliary colic. Diclofenac has higher cardiovascular risk than ibuprofen — use the lowest effective dose for the shortest reasonable time.
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Reactin 50 mg is an immediate-release oral tablet of diclofenac, one of the most potent oral NSAIDs in clinical use worldwide. Diclofenac is on the WHO Essential Medicines List and is the workhorse NSAID for strong anti-inflammatory effect — roughly twice as potent per milligram as ibuprofen.
The 50 mg tablet is the standard adult immediate-release dose for acute pain and chronic inflammatory arthritis. For simpler twice-daily dosing and smoother plasma levels, the sustained-release 100 mg form (Reactin SR) is often preferred in long-term therapy.
What Is Reactin Used For?
- Osteoarthritis and rheumatoid arthritis
- Ankylosing spondylitis
- Acute gout — high-dose short course
- Post-operative pain — dental, orthopaedic, gynaecological
- Acute musculoskeletal injury — sprains, strains, soft-tissue injury
- Primary dysmenorrhoea (period pain)
- Renal and biliary colic — strong visceral pain relief
- Acute migraine (occasionally)
- Low back pain (short course)
How Does Diclofenac Work?
Diclofenac is a non-selective NSAID. It blocks the cyclooxygenase (COX-1 and COX-2) enzymes that convert arachidonic acid to prostaglandins — the molecules that drive pain, swelling, and fever at sites of tissue injury. Less prostaglandin means less pain and inflammation. Because COX-1-derived prostaglandins also protect the stomach lining and regulate kidney blood flow, the same mechanism that gives NSAIDs their benefit also accounts for their main side effects.
Reactin Dosing
- Adults: 50 mg two or three times daily with food
- Maximum: 150 mg/day (three tablets)
- Acute gout: 50 mg three times daily for 2–3 days, tapering as inflammation settles
- Ouderen: lowest effective dose, careful monitoring of blood pressure, kidney function, and GI tolerance
- Nierfunctiestoornis: avoid if CrCl < 30 mL/min
- Leverfunctiestoornis: avoid in severe impairment
Swallow whole with water, with or after food. Space doses by at least 6 hours. Miss a dose: take it when you remember unless the next dose is due within 2 hours — then skip. Never double up.
GI safety. Every oral NSAID — including Reactin — carries real risk of gastritis, peptic ulcer, and upper-GI bleeding. Risk is highest in patients over 65, those with prior ulcer disease, and anyone also on low-dose aspirin, corticosteroids, SSRIs, or anticoagulants. Take Reactin with food, at the lowest effective dose for the shortest reasonable time, and ask your doctor about a proton pump inhibitor (omeprazole, pantoprazole) for courses over 2–4 weeks.
Who Should Not Take Reactin?
- Known hypersensitivity to diclofenac or any NSAID
- Active or recurrent peptic ulcer or GI bleed
- Aspirin- or NSAID-induced asthma, urticaria, or angioedema
- Severe heart failure (NYHA IV), established ischaemic heart disease, peripheral arterial disease, or cerebrovascular disease (use an alternative NSAID)
- Recent CABG surgery
- Ernstige leverfunctiestoornis
- Severe renal impairment (CrCl < 30 mL/min)
- Third trimester of pregnancy
Cardiovascular and renal safety
All non-aspirin NSAIDs carry some increase in heart attack, stroke, and heart-failure risk — particularly diclofenac and COX-2 selectives. They can also raise blood pressure and reduce kidney function, especially in elderly patients and in anyone combining an NSAID with an ACE inhibitor/ARB plus a diuretic. Use the lowest effective dose for the shortest duration, and discuss a long course with your doctor if you have cardiovascular or kidney risk factors.
Bijwerkingen
- Vaak voorkomend: dyspepsia, heartburn, nausea, abdominal pain, diarrhoea or constipation, headache, dizziness, rash, mild ankle swelling
- Minder vaak voorkomend: peptic ulcer, GI bleeding, hypertension, elevated liver enzymes, tinnitus, reduced kidney function
- Zeldzaam: severe hepatotoxicity, Stevens-Johnson syndrome, aseptic meningitis, anaphylaxis, heart failure aggravation
Reactin vs Reactin SR vs Voveran SR
All three products contain diclofenac. They differ in dose and release:
- Reactin 50 mg IR — standard acute and short-course dose; dosed three times daily
- Reactin SR 100 mg — sustained release; once or twice daily; suitable for chronic inflammatory conditions
- Voveran SR 75 mg — sustained release at lower strength; usually twice daily
Bestellen & Levering
MedsBase offers worldwide shipping on every order. Orders are dispatched in discreet packaging and arrive in branded manufacturer packs. If your preferred pack size is out of stock, contact customer support for an ETA.
Medisch disclaimer. The information on this page is provided for general education only. It is not a substitute for advice from your own doctor or pharmacist. Talk to a qualified healthcare professional before starting, stopping, or changing therapy, especially if you have a history of ulcer disease, heart disease, kidney disease, asthma, liver disease, or are pregnant.
Veelgestelde vragen
What is Reactin 50 mg used for?
Reactin (diclofenac 50 mg) is used for acute and chronic pain and inflammation — osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, post-operative pain, musculoskeletal injury, renal colic, and dysmenorrhoea.
How long does Reactin take to work?
Pain relief typically begins within 30–60 minutes of an oral dose; peak effect at 1–2 hours. Anti-inflammatory effect in arthritis builds over 1–2 weeks of regular dosing.
Should I take Reactin with food?
Yes — always. Take with or immediately after food. This reduces gastric irritation and GI side effects.
How is Reactin different from Reactin SR?
Same molecule (diclofenac). Reactin is 50 mg immediate-release, dosed 2–3 times a day. Reactin SR is 100 mg sustained-release, dosed once or twice daily. Reactin is preferred for short acute courses; Reactin SR is better for ongoing inflammatory arthritis.
Is Reactin safer than ibuprofen?
Per milligram, diclofenac is more potent than ibuprofen but carries higher cardiovascular risk. For occasional short-course use, both are acceptable. For longer use and in patients with cardiovascular disease, low-dose ibuprofen or naproxen is generally preferred.
Can I take Reactin with paracetamol?
Yes. Paracetamol acts on a different pathway and is routinely combined with diclofenac for stronger pain relief.
Can I drink alcohol on Reactin?
Light drinking is usually tolerated. Regular or heavy drinking sharply increases GI bleed risk — avoid during treatment.
Is Reactin safe in pregnancy?
Avoid after 20 weeks of pregnancy; absolutely contraindicated in the third trimester (risk of premature ductus arteriosus closure). Use in early pregnancy only under specialist advice.
Can I take Reactin long-term?
For chronic inflammatory arthritis it can be used longer-term at the lowest effective dose, ideally with a proton pump inhibitor and regular review of blood pressure, kidney function, and liver enzymes. For acute musculoskeletal pain, keep the course to 5–10 days.
Can I take Reactin with blood-pressure or heart-failure medication?
Use with caution. Diclofenac can blunt ACE inhibitors, ARBs, and diuretics, and can aggravate heart failure. Short courses are usually manageable; chronic use needs a risk-benefit review with your doctor.
What if I miss a dose of Reactin?
Take it when you remember, unless your next dose is due within 2 hours. Never double up.
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| Sterkte | 50 mg |
|---|---|
| Hoeveelheid | 30 Tabletten, 60 Tabletten, 90 Tabletten, 180 Tabletten |
Reactin
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Reactin
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