Regaine 5%
✅ Stimulates hair growth
✅ Reduces hair loss
✅ Improves hair density
✅ Thickens hair strands
✅ Restores hair volume
Regaine 5% contains Minoxidil Topical Solution.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
💡 Snel antwoord
Regaine 5% is een topical minoxidil solution (5%) for male-pattern hair loss (androgenetic alopecia). Apply twice daily to dry scalp — early shedding in weeks 2–8 is normal. Expect visible regrowth at 3–6 months; full response at 9–12 months. Solution covers a wider area more economically than foam and reaches dense hair more easily. Typically lower cost per month. Downside: the propylene-glycol base can cause itch / flaking in some users — consider switching to foam if this happens.
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What Is Regaine 5%?
Regaine 5% is a topical minoxidil solution at 5% concentration, packaged in a 60 ml bottle. Minoxidil is the only FDA-approved topical drug for androgenetic alopecia (male-pattern baldness). It works primarily by opening potassium channels and stimulating vasodilation in scalp vasculature, extending the anagen (active growth) phase of the hair follicle.
Manufactured by Johnson & Johnson.
Clinical Use
- Androgenetic alopecia (male-pattern baldness): primary indication. Most effective on crown-area thinning; less reliable on the temples/hairline.
- Female-pattern hair loss (FPHL): 2% twice daily or 5% once daily is the FDA-approved female regimen.
- Alopecia areata: used off-label as adjunct to steroid injections, though response is variable.
- Post-chemotherapy hair regrowth: may accelerate return of hair after treatment completes.
How to Apply Regaine 5%
- Make sure your scalp and hair are dry. Damp scalp reduces penetration.
- Using the dropper, apply 1 mL to the dry scalp affected area. Spread with fingertips and let it air-dry for ~4 hours (including overnight). Do not rinse, style, or blow-dry immediately after application.
- Wash hands after application so the drug does not transfer to face, pillow, or other surfaces.
- Apply 1 mL twice daily — morning and evening, roughly 12 hours apart — to dry scalp for best absorption.
- Do not wash, style, or apply other products for at least 4 hours na aanbrengen.
- Expect temporary shedding in weeks 2–8 as dormant follicles synchronise into anagen — this is a positive sign, not a failure.
- Assess response at 3 months (baseline change), 6 maanden (visible regrowth usually), and 9–12 months (peak response).
- Do not stop. Benefits reverse within 3–4 months of discontinuation.
Realistic Expectations
- Ongeveer 40–65% of users see meaningful improvement at 12 months. Crown responds best; hairline worst.
- The first visible change is usually reduced shedding, vervolgens fine regrowth, vervolgens thicker/longer hairs.
- Combining minoxidil with oral finasteride (for men) is more effective than either alone — studies show additive benefit.
- Response plateaus at 1–2 years; lifetime continuous use is needed to maintain gains.
2% vs 5% vs 10% Strength
Efficacy does not scale linearly with concentration. Studies show 5% outperforms 2% by roughly 45% greater hair count increase, but 10% produces only modest additional benefit at significantly higher irritation risk. For most men, 5% is the sweet spot. 10% is reasonable in strong responders who tolerate 5% well but want incremental gains.
See our detailed guide: Minoxidil 5% vs 10% — Is Stronger Actually Better?
Bijwerkingen
Common (local): scalp itching, flaking, redness, dryness. The propylene-glycol vehicle in solution/lotion drives much of this; foam tolerates better.
Minder vaak: facial hair growth from drug run-off, transient increased shedding at weeks 2–8 (a good sign), contact dermatitis.
Rare serious: chest palpitations, ankle swelling, rapid heart rate (from systemic absorption with whole-scalp use and damaged skin). Discontinue and seek medical review if these occur.
Who Should Not Use Regaine 5%
- Known hypersensitivity to minoxidil or excipients (including propylene glycol in liquid formulations)
- Acute scalp inflammation, open wounds, eczema, psoriasis at application site — systemic absorption rises sharply
- Severe uncontrolled cardiovascular disease — consult cardiologist before use
- Pregnancy or breastfeeding — avoid; safer dermatologic alternatives exist
- Age under 18 — not studied
Combining with Finasteride
Minoxidil + oral finasteride is the evidence-based combination for men with androgenetic alopecia — one drug addresses the DHT upstream cause, the other stimulates follicle growth. Studies consistently show combination therapy outperforms either alone. See products Finpecia (1 mg), Finrest (1/5 mg), of Proscalpin (1 mg) and our Finasteride vs Dutasteride Guide.
Opslag
Store at room temperature (15–25 °C / 59–77 °F), away from direct heat, flame (liquid formulations are flammable), and sunlight. Replace cap tightly. Keep out of reach of children and pets — minoxidil is toxic to cats. Do not use after the printed expiry date.
Veelgestelde vragen
When will I see results from Regaine 5%?
Reduced shedding appears around 2–3 months. Visible regrowth is typical at 4–6 months. Peak response at 9–12 months. Temporary increased shedding in the first 2–8 weeks is expected and is actually a sign the drug is working (old telogen hairs being pushed out).
What if I stop using Regaine 5%?
Newly grown hairs revert to baseline within 3–4 months of discontinuation. Long-term benefit requires continuous use. Plan for minoxidil as a lifetime commitment — if you stop, expect the hair gained to be lost.
Can I use Regaine 5% together with finasteride?
Yes — this combination is considered the gold standard for male-pattern baldness. Topical minoxidil + oral finasteride 1 mg is more effective than either alone. If tolerated, many dermatologists recommend combining them from the start.
Is the initial shedding a bad sign?
No — it is expected and reflects synchronization of follicles into active growth phase. Shedding peaks at 4–8 weeks and resolves by 3 months. If shedding persists past 4 months without regrowth, speak to a clinician.
Which strength should I use?
Most men start at 5% twice daily. 2% is suitable for women or men with prior irritation. 10% is for men who tolerate 5% well but want incremental gains. See our 5% vs 10% guide.
Will Regaine 5% work on the hairline and temples?
Less reliably than the crown. Minoxidil’s strongest response is crown-area (vertex) thinning. Hairline and temple recession respond less well — consider adding oral finasteride for those areas.
Can I apply it more than twice daily?
No. Twice daily is the FDA-approved schedule. More frequent application does not speed results and increases irritation + systemic absorption risk.
Is Regaine 5% safe for women?
Yes at 2% twice daily or 5% once daily (FDA-approved). Avoid during pregnancy and breastfeeding. Unwanted facial hair is more common at 5%.
Can I colour or style my hair while using Regaine 5%?
Yes, but wait at least 4 hours after application before washing or applying styling products. Avoid bleaching the scalp while on minoxidil — it raises irritation and shedding risk.
Will minoxidil cause permanent scalp damage?
No — minoxidil is not known to cause permanent scalp damage. Irritation resolves with formulation change (foam vs solution) or brief pause. Long-term use has a strong safety record since 1988.
Gerelateerde producten & gidsen
- Finasteride vs Dutasteride Guide
- Minoxidil 5% vs 10% Guide
- Everything About Hair Loss
- How to Stop Hair Loss
- Can You Prevent Hair Loss?
- Tugain Foam (Minoxidil 5%)
- Tugain Solution (Minoxidil 10%)
⚕️ Medische disclaimer: Information on this page is for educational purposes and does not replace medical advice. Always consult a qualified clinician before starting, stopping, or changing any medication. Prescription products should be used only under medical supervision.
Regaine 5% is the topical minoxidil 5% standard for male-pattern hair loss; users who develop scalp irritation, who can’t tolerate the topical vehicle, or who prefer a once-daily pill can switch to Minoxytop (oral minoxidil 5 mg) as the systemic-route alternative.
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| Sterkte | 5% w/v 60 ml |
|---|---|
| Hoeveelheid | 1 Fles/s, 2 Flessen/s, 3 Flessen/s, 6 Flessen/s |
Regaine 5%
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Regaine 5%
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