Celin
✅ Versterkt het immuunsysteem
✅ Supports collagen production
✅ Enhances wound healing
✅ Acts as antioxidant
✅ Improves iron absorption
Celin contains Vitamin C.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
Snelle antwoord
Celin (ascorbic acid (vitamin C) 500 mg tablet (GSK)) is high-dose oral vitamin C for prevention and treatment of vitamin C deficiency, scurvy, immune support, and as an adjunct to iron absorption in iron-deficiency anaemia.
- Vitamin C 500 mg per tablet — therapeutic dose
- Indications: scurvy, deficiency, iron-absorption support, wound healing, smokers
- Standard dose: 1 tablet daily; deficiency states up to 1 g/day
- WHO-GMP certified manufacturer (GSK)
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What is Celin?
Celin is high-dose oral ascorbic acid (vitamin C) at 500 mg per tablet. Vitamin C is a water-soluble antioxidant essential for collagen synthesis, iron absorption, immune function, and as a cofactor for catecholamine and carnitine synthesis. Adult recommended daily intake is 75–90 mg/day; therapeutic doses for deficiency or specific indications use 250–1,000 mg/day.
Indicaties
- Vitamin C deficiency / scurvy — classical bleeding gums, perifollicular haemorrhage, fatigue, wound dehiscence; treat with 500–1,000 mg/day for several weeks then RDA
- Iron-deficiency anaemia adjunct — vitamin C taken with oral iron meaningfully increases non-haem iron absorption
- Smokers — smoking depletes vitamin C; smokers need ~35 mg/day more than non-smokers
- Wound healing — collagen synthesis cofactor; supplementation in deficient surgical patients
- Pre-eclampsia adjunct — mixed evidence; specialist call
- G6PD deficiency haemolysis prophylaxis — modest evidence at high doses
- Common cold — small reduction in duration if started before symptoms; no benefit once symptoms have started
- Methaemoglobinaemia — second-line, after methylene blue
How to take
One tablet daily with food for general supplementation. For deficiency or therapeutic indications, 1–2 tablets daily. Vitamin C absorption is dose-dependent — absorption efficiency drops sharply above 200 mg in a single dose, so splitting larger total doses across the day is more efficient.
Bijwerkingen
- Milde maag-darmklachten — nausea, diarrhoea, dyspepsia at doses >1 g/day
- Kidney stones — sustained high-dose vitamin C (>2 g/day) may increase calcium-oxalate stone formation in predisposed patients
- False-negative stool guaiac, false-positive urine glucose — lab interference
- Iron overload risk in haemochromatosis or thalassaemia — vitamin C boosts iron absorption
Megadose oral or IV vitamin C has been popularised for cold prevention, COVID-19, sepsis, and cancer. Evidence: oral vitamin C started before symptoms reduces cold duration by 8–14% (small effect); started after symptoms onset, no clear benefit. IV vitamin C in sepsis: large RCTs (LOVIT, VICTAS) showed no benefit and possible harm. COVID-19: no benefit in RCTs. Cancer: no high-quality evidence of meaningful benefit. Use Celin for documented deficiency and the few clear adjunctive indications — not as universal cure-all.
Geneesmiddelinteracties
- Oral iron — vitamin C improves absorption; intentional combination in iron-deficiency anaemia
- Aluminium-containing antacids — vitamin C increases aluminium absorption
- Warfarine — high-dose vitamin C (>1 g/day) may modestly reduce INR; relevant only at sustained high doses
- Oestrogen contraceptives — vitamin C may increase oestrogen levels; clinically rarely significant
- Deferoxamine — combination increases iron mobilisation; specialist combination only with cardiac monitoring
- Chemotherapy — theoretical antioxidant interference; oncology patients should disclose vitamin C use
Contra-indicaties
- Hyperoxaluria, recurrent calcium-oxalate kidney stones (relative; avoid sustained high-dose)
- Haemochromatosis, thalassaemia (avoid high-dose — iron overload)
- G6PD deficiency in haemolytic crisis (paradoxically megadose IV can trigger oxidative haemolysis at very high doses; standard oral is fine)
Opslag
Store below 25°C in original packaging, protect from light and moisture.
Veelgestelde vragen
Will Celin prevent or shorten colds?
Routine daily vitamin C supplementation reduces cold duration by about 8–14% (small effect) and may reduce cold incidence in people under physical stress (athletes, soldiers in cold climates). Started AFTER symptoms appear, no clear benefit. So preventive use is worth it for athletes and high-stress contexts; reactive use is mostly placebo.
Does vitamin C boost iron absorption?
Yes, meaningfully. Take Celin with your iron tablet to roughly double non-haem iron absorption. This is one of the cheapest and best-evidenced adjuncts in iron-deficiency anaemia management.
Should smokers take more vitamin C?
Yes — smokers metabolise vitamin C faster and need about 35 mg/day more than non-smokers. A 500 mg Celin daily covers this with margin to spare.
How much is too much?
Tolerable upper intake is about 2,000 mg/day for adults. Above this, GI side effects (osmotic diarrhoea), kidney stone risk in predisposed patients, and iron overload risk in haemochromatosis become concerns.
Will it help my immune system?
Adequate vitamin C is necessary for immune function — deficiency clearly impairs it. Megadose vitamin C in non-deficient adults does not enhance immunity beyond baseline. Replace if deficient; otherwise focus on sleep, diet, exercise.
Is it safe in pregnancy?
Yes at standard doses (75–120 mg/day; up to 500 mg if deficient). Megadose >1 g/day routinely is not recommended in pregnancy.
Will it help wound healing?
In deficient patients, yes — vitamin C is a collagen-synthesis cofactor. In well-fed patients with normal vitamin C status, supplementation has not been shown to speed surgical healing. Worth supplementing in malnourished or chronic-wound patients.
Can I take it with iron supplements?
Yes — this is the recommended combination. Vitamin C reduces ferric iron to ferrous iron (the absorbable form) and chelates it for transport across the gut wall.
Will high-dose vitamin C cause kidney stones?
In patients without a stone history, the increase in calcium-oxalate stone risk at standard doses is minimal. Risk rises with sustained >2 g/day or with a personal history of recurrent calcium-oxalate stones. Stay well-hydrated; halve the dose if a stone history is present.
Should I take buffered or chewable vitamin C?
Buffered (calcium ascorbate, sodium ascorbate) is gentler on the stomach for sensitive patients but otherwise equivalent. Chewable formulations contain sugar or sweeteners and may erode dental enamel with prolonged direct contact.
Andere Vitamines & Mineralen
- Celin — vitamin C 500 mg
- C Vitan Z — vitamin C + zinc + minerals
- L-Glutathione — reduced glutathione antioxidant
- Multivite Gold — uitgebreide multivitamine
- Becozinc — B-complex with zinc
- Cheri — iron + protein + calcium + vitamins
Medische Disclaimer
Meer opties in Vitaminen en Mineralen
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Sterkte | 500 mg |
|---|---|
| Hoeveelheid | 25 Tablet/s, 50 Tablet/s, 75 Tablet/s, 150 Tablet/s, 300 Tablet/s |
Celin
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