⚡ Quick Answer — What is Alaspan?
Alaspan bevat loratadine 10 mg, een second-generation non-sedating H1 antihistamine gedurende allergic rhinitis (hay fever), chronic urticaria, en allergic skin conditions. Onset is within 1 uur; effect lasts 24 hours — once-daily dosing. Loratadine is non-sedating in most users (less than 8% report drowsiness vs ~30% with first-generation antihistamines). Manufactured by Merck & Co; international brand Claritin.
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What Is Alaspan?
Alaspan contains loratadine, one of the most-used second-generation antihistamines worldwide. It is on the WHO List of Essential Medicines. The active metabolite is desloratadine (sold separately as Aerius). Loratadine has minimal CNS penetration, giving negligible sedation in most users.
How Does Loratadine Work?
Loratadine selectively blocks peripheral H1 histamine receptors with high specificity. By preventing histamine binding, it relieves itching, sneezing, runny nose, watery eyes, and skin wheals. It does not cross the blood-brain barrier in significant amounts at therapeutic doses, hence the lack of sedation that characterises first-generation antihistamines (chlorpheniramine, diphenhydramine).
Toepassingen en Indicaties
- Allergic rhinitis — seasonal (hay fever) and perennial
- Chronic spontaneous urticaria — hives
- Allergische conjunctivitis
- Atopic dermatitis adjunct — for itching
- Insect-bite reactions
- Adjunct in allergic asthma with concurrent rhinitis
Alaspan Dosage
| Patient | Dosering | Frequentie |
|---|---|---|
| Adults & children >30 kg | 10 mg | Eénmaal daags |
| Children 2–12 yr (≤30 kg) | 5 mg | Eénmaal daags |
| Ernstige leverfunctiestoornis | 10 mg | Every other day |
Side Effects of Alaspan
- Headache (common)
- Mild fatigue or drowsiness in <8% of users
- Droge mond
- Mild abdominal pain or nausea
- Rarely: tachycardia, hair loss, photosensitivity
Serious — stop and seek help:
- Ernstige allergische reactie
- Severe palpitations or arrhythmia (very rare)
Waarschuwingen en voorzorgsmaatregelen
- Leverfunctiestoornis: reduce dose frequency in severe disease.
- Driving and machinery: usually safe — but a small minority report drowsiness; assess individual response.
- Zwangerschap: reasonable safety data; loratadine is among the better-studied second-generation antihistamines in pregnancy.
- Nierfunctiestoornis: dose reduction is not generally needed.
- Allergic asthma: Alaspan helps the rhinitis component but does not control bronchospasm — keep your asthma medications.
Contra-indicaties
- Hypersensitivity to loratadine or desloratadine
Geneesmiddelinteracties
- Strong CYP3A4 inhibitors (ketoconazole, erythromycin, cimetidine) — modestly increase loratadine levels; clinically usually insignificant
- Alcohol — minimal interaction at therapeutic doses (unlike first-generation antihistamines)
Opslag
- Store below 25°C in a cool, dry place away from direct sunlight.
- Keep in original packaging until use to protect from moisture and light.
- Do not use after the expiry date printed on the strip.
- Keep out of reach of children.
Gerelateerde alternatieven op MedsBase
- Cetcip-L — levocetirizine antihistamine
- Flomist Nasal Spray — fluticasone for rhinitis
- Budenase AQ Nasal Spray — budesonide nasal
- Montair — montelukast LTRA
- Asthafen — ketotifen mast-cell stabiliser
Veelgestelde vragen
Is Alaspan the same as Claritin?
Yes — both contain loratadine 10 mg. Claritin (Bayer / formerly Schering-Plough) is the international brand; Alaspan is an Indian-market generic.
Will Alaspan make me drowsy?
Less than 8% of users report drowsiness — most people can drive and work normally on it. If drowsy, take it at night.
How long does Alaspan take to work?
Onset within 1 hour; full effect within 3 hours; duration 24 hours.
Can children take Alaspan?
Yes from age 2 in age-appropriate strength (5 mg under 30 kg; 10 mg above 30 kg).
Is Alaspan safe in pregnancy?
Yes — loratadine has reassuring observational pregnancy data. It is among the preferred antihistamines in pregnancy.
How does Alaspan compare to cetirizine or fexofenadine?
All three are non-sedating second-generation H1 antihistamines. Cetirizine has slightly more potential drowsiness than loratadine. Fexofenadine has the lowest drowsiness rate. All are equally effective for most allergy symptoms.
Can Alaspan replace my inhaler for asthma?
No — antihistamines treat the rhinitis component but do not control asthma bronchospasm. Continue your inhalers.
How long can I take Alaspan?
Long-term daily use is acceptable for chronic urticaria and perennial rhinitis. No tolerance develops with chronic use.
Can I take Alaspan with my other allergy medications?
Yes — loratadine combines well with intranasal steroids (Flomist, Furamist), montelukast (Montair), and short antihistamine eye drops. Discuss the regimen with your prescriber.






























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