Snelle antwoord
Feronia-XT (ferrous ascorbate + folic acid tablet) is an oral iron tablet combining ferrous ascorbate (a chelated iron form with built-in vitamin C) with folic acid for combined iron-deficiency anaemia and folate replacement in pregnancy and post-partum.
- Ferrous ascorbate (iron-vitamin-C chelate) + folic acid 1.5 mg
- Built-in vitamin C improves absorption and tolerability vs ferrous sulphate
- Indications: iron-deficiency anaemia, pregnancy, post-partum, megaloblastic anaemia adjunct
- WHO-GMP gecertificeerde fabrikant
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What is Feronia-XT?
Feronia-XT is an oral iron tablet using ferrous ascorbate — a chelated iron form where the iron is bound to ascorbate (vitamin C) within the molecule. This built-in vitamin C improves absorption efficiency and reduces GI side effects compared to traditional ferrous sulphate. The added folic acid (typically 1.5 mg) addresses combined iron-and-folate deficiency, common in pregnancy.
Indicaties
- Iron-deficiency anaemia — menstrual loss, pregnancy, GI blood loss, dietary insufficiency
- Iron deficiency without anaemia — ferritin < 30 ng/ml with fatigue, restless legs, hair loss, pica
- Zwangerschap — routine prophylaxis after the first trimester in many guidelines
- Adolescent menarche — particularly in vegetarian / vegan diets
- Post-partum anaemia
- Pre-operative optimisation for elective surgery in anaemic patients
- Bariatric surgery follow-up — iron malabsorption is common
- Chronische nierziekte with iron deficiency (often combined with ESA therapy)
Hoe in te nemen
One tablet once daily — preferably alternate days for better absorption efficiency. The ferrous ascorbate formulation is generally better tolerated than ferrous sulphate; food helps if any nausea persists. Avoid simultaneous tea, coffee, dairy, or calcium-rich meals.
Recent trials (Stoffel 2017, Moretti 2015) show that taking oral iron every other day rather than daily — or splitting the daily dose — improves fractional absorption and reduces GI side effects. Daily dosing triggers hepcidin upregulation that blocks subsequent doses for 24 hours. Consider one tablet every other morning rather than two tablets daily.
Bijwerkingen
- Black or dark stools — expected, not a problem
- Constipation, abdominal cramps, nausea — the most common reasons for adherence failure; alternate-day dosing or switching iron salt helps
- Dyspepsia, metallic taste
- Tooth staining with liquid iron preparations (rinse mouth after dosing)
- Iron overdose — serious in children; keep well out of reach
Geneesmiddelinteracties
- Calcium, antacids, tetracyclines, fluoroquinolones, levothyroxine, bisphosphonates — chelation; separate by 2–4 hours
- Vitamin C — intentional combination; vitamin C improves iron absorption
- Tea, coffee, cocoa — tannins inhibit iron absorption; separate by 1–2 hours
- Levodopa, methyldopa, penicillamine — reduced absorption
- PPIs and H2 blockers — reduced ferrous iron absorption (acid environment helps)
Contra-indicaties
- Iron overload (haemochromatosis, repeated transfusions, thalassaemia)
- Haemolytic anaemia without iron deficiency
- Active gastrointestinal bleeding without correction of source
Opslag
Store below 25°C, dry, in original packaging. Keep out of reach of children — iron overdose is a leading cause of fatal pediatric poisoning.
Veelgestelde vragen
Why is my stool dark?
Unabsorbed iron passes through and turns stool black or dark green. Expected, harmless — not a sign of GI bleeding.
Hoelang duurt het voordat ik verbetering merk?
Reticulocyte response by day 5–7. Haemoglobin rises ~1 g/dl per 2–3 weeks. Full ferritin replenishment takes 3–6 months — do not stop at first normal Hb. Symptoms (fatigue, breathlessness) improve over 4–8 weeks.
Should I take it on an empty stomach?
Empty stomach (1 hour before food) gives best absorption but worst tolerability. With food reduces absorption by ~40–50% but improves tolerability and adherence. Most patients do better with food — just take it for longer to make up.
When should I take vitamin C with it?
Take vitamin C (Celin 500 mg) at the same time as the iron tablet. Vitamin C reduces ferric to ferrous iron and chelates it for transport — roughly doubles non-haem iron absorption.
Why alternate-day dosing?
Daily iron triggers hepcidin (the master iron-blocker hormone) for 24 hours, so the next dose absorbs poorly. Alternate-day dosing lets hepcidin fall between doses, improving total absorption per week with fewer GI side effects.
How long do I need to take it?
Until ferritin is > 50 ng/ml AND haemoglobin is normal AND the underlying cause has been managed. Typically 3–6 months total. Stopping at first normal Hb leaves ferritin low and the deficiency relapses within months.
Should I have IV iron instead?
Oral iron is first-line for most. IV iron is preferred when: oral iron is not tolerated despite alternate-day dosing, malabsorption (coeliac, IBD, post-bariatric), severe deficiency needing rapid correction (third-trimester pregnancy, pre-op), CKD on ESA therapy, ongoing blood loss outpacing oral absorption.
Can I take it in pregnancy?
Yes — iron deficiency in pregnancy worsens fatigue, increases preterm-birth risk, and impairs fetal iron stores. Routine third-trimester iron is widely recommended. Severe anaemia in late pregnancy may need IV iron.
Why is iron deficiency tested for in adults?
Common causes: heavy menstrual bleeding (often the answer in pre-menopausal women), pregnancy, GI blood loss (peptic ulcer, colon cancer, hookworm), dietary inadequacy, malabsorption (coeliac, post-bariatric), chronic disease. New iron deficiency in a man or post-menopausal woman warrants GI investigation.
What if it makes me really nauseous?
Try: take with food, alternate-day dosing, halve the dose, switch iron salt (ferrous fumarate vs ferrous gluconate vs ferrous bisglycinate — tolerability varies). If still intolerant after these adjustments, consider IV iron.
Andere Vitamines & Mineralen
- Fesovit — ferrous fumarate + vitamin C + B-complex
- Feronia-XT — ferrous ascorbate + folic acid
- Cheri — iron + protein + calcium + vitamins
- Vitamine B12 1500 mcg — oral cyanocobalamin for combined-deficiency anaemia
- Celin — vitamin C 500 mg (improves iron absorption)
- Multivite Gold — uitgebreide multivitamine



























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