Pirox Gel
✅ Pain relief
✅ Reduces inflammation
✅ Joint mobility improvement
✅ Muscle relaxation
✅ Topical application
Pirox Gel contains Piroxicam.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Pirox Gel?
Pirox Gel is een piroxicam 0.5% topical gel used for the localised treatment of musculoskeletal and soft-tissue pain — sprains, strains, tendonitis, bursitis, and small-joint osteoarthritis. Apply 3 to 4 times daily for up to 14 days. Because piroxicam causes photosensitivity in a minority of users, avoid sun exposure on the treated area for 2 weeks after the last application.
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Pirox Gel 0.5% (30 g) is a topical piroxicam preparation. Piroxicam is a long-acting oxicam-class NSAID that, when applied to the skin, penetrates to underlying soft tissue and joint capsule in sufficient concentration to reduce local inflammation — without the systemic side-effect burden of oral piroxicam (which has a 50-hour half-life and a prolonged systemic exposure profile).
Topical piroxicam is well established for acute traumatic and chronic musculoskeletal pain. It is widely used in Europe and Asia, and is included on several national formularies for the outpatient management of sports injuries and soft-tissue rheumatism.
What Is Pirox Gel Used For?
- Acute sports injuries and soft-tissue trauma — sprains, strains, contusions
- Tendonitis, tenosynovitis, bursitis, epicondylitis (tennis/golfer’s elbow)
- Osteoarthritis of the hand, knee, and ankle
- Periarticular rheumatic conditions
- Localised lower back pain, neck pain, shoulder pain
- Post-exercise delayed-onset muscle soreness (DOMS)
How Does Pirox Gel Work?
Piroxicam inhibits both cyclooxygenase isoforms in inflamed tissue, reducing local prostaglandin synthesis. The topical formulation delivers piroxicam to the dermis and underlying structures while keeping blood levels low — typically less than 5% of an oral dose. This makes it a rational choice when localised inflammation is the main driver of pain.
How to Apply Pirox Gel
- Wash your hands and the skin area with mild soap and water; dry thoroughly.
- Squeeze a small ribbon (about the size of a cherry for a single knee, a grape for a wrist or elbow) onto the painful area.
- Gently rub in until absorbed — this usually takes 30–60 seconds.
- Wash your hands with soap and water after application (unless you are treating your hands).
- Do niet cover the area with an occlusive dressing (cling film, tight bandage, waterproof plaster) unless your doctor specifically recommends it — occlusion increases systemic absorption.
- Keep the gel away from broken skin, eyes, lips, and mucous membranes.
How often: 3 to 4 times daily. Maximum in 24 hours: about 8 g (about a 6-cm ribbon of gel per application on a single large joint) (roughly the size of a large walnut). Treatment courses are usually 7–14 days; longer use should be reviewed by a doctor.
Safety notes for Pirox Gel. Topical NSAIDs are not risk-free. Although systemic absorption is low (typically 5–10% of an equivalent oral dose), large treatment areas, occlusive dressings, broken skin, or long-duration use can push absorption into a range that matters — particularly in people with kidney disease, heart failure, prior peptic ulcers, or late pregnancy. Do not combine Pirox Gel with an oral NSAID unless your doctor has specifically recommended it.
Photosensitivity warning. Piroxicam, including topical piroxicam, can cause photosensitive skin reactions — abnormal sunburn, rash, or blistering on skin that has been exposed to UV light. Protect the treated area from direct sunlight for the duration of therapy and for at least 2 weeks after the last application. Do not use a sunbed while on Pirox Gel. Seek medical advice if any rash develops on a sun-exposed area.
Who Should Not Use Pirox Gel?
- Known hypersensitivity to the active ingredient or to any NSAID
- A history of asthma, urticaria, or angioedema triggered by aspirin or an NSAID
- Broken skin, open wounds, infected skin, or active eczema at the application site
- Children under 12 years (topical NSAID use should be specialist-guided)
- Third trimester of pregnancy (NSAID class effect on fetal ductus arteriosus)
Use with caution if you are already taking an oral NSAID, low-dose aspirin, or if you have severe kidney or liver disease.
Veelvoorkomende bijwerkingen
Most users tolerate topical NSAID gels well. Effects are usually mild and local.
- Vaak voorkomend: skin irritation at the application site — tingling, mild burning, redness, or dryness
- Minder vaak voorkomend: contact dermatitis, pruritus, rash extending beyond the application area
- Zeldzaam: photosensitivity (especially with piroxicam gel), severe skin reactions, systemic NSAID effects in heavy long-term use
Stop the gel and contact your doctor if you develop a widespread rash, blistering, skin peeling, mouth ulcers, or any signs of a systemic NSAID effect (indigestion, ankle swelling, unusual bruising).
Bestellen & Levering
MedsBase offers worldwide shipping on every order. Orders are dispatched in discreet packaging and arrive in branded manufacturer packs. If your preferred pack size is out of stock, contact customer support for an ETA.
Medisch disclaimer. The information on this page is provided for general education only. It is not a substitute for advice from your own doctor or pharmacist. Talk to a qualified healthcare professional before starting, stopping, or changing therapy, especially if you have a history of ulcer disease, heart disease, kidney disease, asthma, liver disease, or are pregnant.
Veelgestelde vragen
What is Pirox Gel used for?
Pirox Gel (piroxicam 0.5%) is used for localised musculoskeletal and soft-tissue pain — sprains, strains, tendonitis, bursitis, and small-joint osteoarthritis.
How is topical piroxicam different from oral piroxicam?
Same molecule. Topical use delivers piroxicam locally with very low systemic absorption, so it avoids the long (~50 h) oral half-life and the systemic GI, CV, and renal exposure that make oral piroxicam a second-line NSAID.
Why do I need to keep the area out of the sun?
Piroxicam has a known risk of photosensitivity — an unusually strong reaction to UV that can present as a rash or blister. The reaction can occur for up to 2 weeks after you stop applying the gel. Keep the treated skin covered from direct sun.
Can I use Pirox Gel under a bandage?
Avoid tight occlusive dressings. A loose, breathable covering is acceptable.
Can I use Pirox Gel and an oral NSAID together?
Only on medical advice. Combining topical and oral NSAIDs adds systemic exposure without much additional local benefit.
How long can I use Pirox Gel?
Treatment courses are usually 7–14 days. Review with your doctor before continuing beyond that.
Can I apply Pirox Gel on my face or neck?
Avoid the face, eyelids, mouth, and mucous membranes. Neck application (e.g. for localised muscle pain) is acceptable on small, intact areas of skin.
Is Pirox Gel safe in pregnancy?
Avoid in the third trimester (NSAID class effect). In early pregnancy, use only if clearly needed and on medical advice.
Will Pirox Gel stain my clothes?
No. The gel is clear and dries without residue. Allow 2–3 minutes absorption before dressing.
Can children use Pirox Gel?
Not recommended under 12 years without medical advice.
What should I do if I develop a rash?
Stop using Pirox Gel and contact your doctor. Document whether the rash is on a sun-exposed area — this changes the interpretation.
Zie ook: lidocaine topical jelly (Lox 2%) — Neon Labs lidocaine 2% topical gel for haemorrhoids, urinary catheterisation, premature ejaculation and minor procedures.
Topical users of Pirox Gel (piroxicam) managing surface-level joint or tendon inflammation sometimes pair the topical NSAID with oral Emanzen Forte (serratiopeptidase 10 mg) when deeper swelling and fibrin deposits require systemic enzymatic clearance as well.
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| Sterkte | 0.5% w/w 30 g |
|---|---|
| Hoeveelheid | 1 Tube/s, 2 Tube/s, 3 Tube/s, 6 Tube/s |
Pirox Gel
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