Poxet
✅ Prolongs Bedtime Performance
✅ PE Delay Specialist
✅ Mastering Ejaculation Timing
✅ On-Demand Enhancement
✅ Satisfaction Upgrade
✅ Priligy® Generic Choice
Poxet contains Dapoxetine
✓ Lékařsky ověřeno Morgan Ellis — Pharmacy Researcher · 8 years experience Last reviewed: May 2026
⚡ Quick Answer — What is Poxet?
Poxet obsahuje dapoxetine and is used for premature ejaculation (PE). Available in 30 / 60 / 90 mg. Klinický účinek trvá přibližně 3 to 5 hours. Manufactured by Sunrise Remedies.
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Poxet obsahuje dapoxetine, the first and only prescription medication developed specifically for the treatment of premature ejaculation (PE). Unlike erectile-dysfunction drugs, dapoxetine does not treat weak erections — it extends intravaginal ejaculatory latency time (IELT) in men with lifelong or acquired PE.
Manufactured by Sunrise Remedies, Poxet is a short-acting selective serotonin reuptake inhibitor (SSRI) engineered with a very short half-life — so it can be dosed on-demand before intimacy rather than taken daily as a standard SSRI.
What Is Poxet?
Poxet is a prescription short-acting SSRI used on-demand to extend ejaculatory latency in men with PE. It is the active ingredient in Priligy®, the first PE medication approved in Europe.
PE is defined clinically as ejaculation that occurs within about one minute of vaginal penetration and causes distress to the man or his partner. Dapoxetine is indicated for men with:
- Lifelong PE — present from the start of sexual life
- Acquired PE — developed after a period of normal function
- Co-existing ED and PE — where dapoxetine is combined with a PDE5 inhibitor under medical supervision
How Does Poxet Work?
Ejaculation is a reflex coordinated by serotonergic neurons in the spinal cord and brainstem. Dapoxetine works by:
- Selectively inhibiting the serotonin transporter (SERT) at central nerve terminals
- Raising synaptic serotonin levels, which delays the ejaculatory reflex
- Acting quickly (onset ~1 hour) and clearing quickly (half-life ~1.5 hours for the parent compound) — so the effect is confined to the sexual encounter rather than persisting all day
In clinical trials, dapoxetine typically extends IELT by 2 to 3 times the baseline, with responders reporting improved control, reduced distress, and higher partner satisfaction.
Dapoxetine is not an ED drug. If you have both ED and PE, a PDE5 inhibitor is required alongside dapoxetine — either as separate tablets or as a combination product such as Super Tadalis Sx nebo Super Vilitra.
Použití a indikace
- Premature ejaculation (PE) — lifelong or acquired, in men aged 18–64
- Combined ED and PE — co-administered with a PDE5 inhibitor (specialist oversight recommended)
Poxet Dosage and Administration
| Scénář | Doporučená dávka | Frekvence / Načasování |
|---|---|---|
| PE — starter dose | 30 mg | 1–3 hours before intended activity; max 1 dose / 24 h |
| PE — inadequate response | 60 mg | Step up after 4 weeks if 30 mg gives suboptimal response; max 1 dose / 24 h |
| Elderly (65+) | Not recommended | Safety data insufficient above age 64 |
| Mild hepatic impairment | 30 mg, max once daily | No dose escalation |
| Moderate–severe hepatic impairment | Kontraindikováno | Avoid entirely |
| Severe renal impairment | Not recommended | Insufficient data |
| Maximální denní dávka | 60 mg per 24 hours | On-demand only — not for daily SSRI use |
How to Take Poxet Properly
- Swallow the tablet whole with a full glass of water — reduces the risk of dizziness and syncope
- Take 1–3 hours before anticipated activity
- Can be taken with or without food
- Do not take more than one dose in 24 hours
- Avoid alcohol — the combination sharply increases dizziness, syncope risk, and impairs judgement
- If you feel dizzy or faint, lie down immediately to prevent injury
Side Effects of Poxet
Dapoxetine has a distinctive side-effect profile — different from PDE5 inhibitors.
| Závažnost | Vedlejší účinek |
|---|---|
| Časté (≥1 z 10) | Nausea, dizziness, headache |
| Časté (≥1 ze 100) | Dry mouth, fatigue, diarrhoea, insomnia, anxiety, somnolence |
| Méně časté | Syncope (fainting), orthostatic hypotension, sinus bradycardia |
| Vzácné | Serotonin syndrome (mainly with MAOIs or other serotonergic drugs), mania, severe allergic reactions |
Syncope warning: 0.05–0.1% of patients experience transient syncope within the first hour. Always take dapoxetine with a full glass of water, sit or lie down if you feel lightheaded, and avoid situations where sudden dizziness could cause harm.
Varování a opatření
- Do not combine with MAOIs (phenelzine, tranylcypromine, linezolid, moclobemide) — risk of serotonin syndrome. Allow 14 days washout after stopping an MAOI
- Do not combine with other serotonergic agents — SSRIs, SNRIs, tricyclics, tramadol, St John’s wort, triptans — without specialist advice
- Cardiac conditions — avoid in significant heart disease (heart failure NYHA II+, heart-block, coronary disease, arrhythmia)
- Mental-health history — avoid in mania, bipolar disorder, or severe depression
- Dehydration / volume depletion — worsens syncope risk; hydrate before dosing
- Driving — dapoxetine can cause dizziness and drowsiness. Do not drive or operate machinery for 24 hours after dosing
Contraindications — Who Should NOT Take Poxet
- MAOI use within the last 14 days
- Thioridazine use
- History of mania or severe depression
- Significant structural cardiac disease (heart failure, ischaemia, valvular disease, arrhythmia)
- Moderate–severe hepatic impairment
- Age <18 or >64
- Hypersensitivity to dapoxetine
Interakce s léčivy
| Léčivo / Třída | Interakce |
|---|---|
| MAOIs, moclobemide, linezolid | Absolutní kontraindikace — serotonin syndrome risk |
| Other SSRIs, SNRIs, tricyclics | Additive serotonergic effect — avoid combination |
| Tramadol, triptans, St John’s wort, lithium | Increased serotonin syndrome risk |
| Potent CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin) | Raise dapoxetine levels — dose reduction or avoidance |
| PDE5 inhibitors (sildenafil, tadalafil, vardenafil) | Additive blood-pressure lowering — use together only under supervision |
| Alkohol | Increases syncope and dizziness — avoid |
Share a full list of prescription and non-prescription medications, including recreational drugs and herbal supplements, with your prescriber before starting Poxet.
Co dělat v případě předávkování
Dapoxetine overdose can cause severe nausea, dizziness, hypotension, syncope, and in rare cases serotonin syndrome (agitation, tremor, tachycardia, hyperthermia). Management is supportive. Contact your local poisons service or emergency department immediately.
Pokyny k uchovávání
- Skladujte pod 30 °C na suchém místě, mimo přímé sluneční světlo
- Uchovávejte v původním blistru až do použití
- Uchovávejte mimo dosah dětí a domácích zvířat
- Nepoužívejte po datu expirace uvedeném na obalu
- Nepoužité tablety likvidujte prostřednictvím lékárny, pokud je k dispozici
Související alternativy na MedsBase
Hledáte související možnosti léčby ED nebo sexuálního zdraví?
- Modula — tadalafil 5 mg, ideální pro jednou denní nízkou dávku
- Vidalista — Centurion Labs tadalafil, 2,5 až 80 mg
- Tadacip — Cipla tadalafil 20 mg
- Megalis — Macleods tadalafil 10 mg / 20 mg
- Suhagra — Cipla sildenafil 25/50/100 mg
- Prohlédnout všechny léčebné přípravky na erektilní dysfunkci →
Často kladené dotazy
Is Poxet an erectile dysfunction drug?
No. Dapoxetine treats premature ejaculation, not erectile dysfunction. If you have both ED and PE, you need a PDE5 inhibitor in addition to dapoxetine — either separately or as a combination tablet.
How quickly does Poxet work?
Peak plasma is reached in about 1 hour. Take 1–3 hours before intended activity for best results.
How long does Poxet last?
The active window is roughly 3–5 hours. The parent compound has a half-life of ~1.5 hours, but an active metabolite extends the effective duration.
How much longer will I last on Poxet?
Clinical trials show that Poxet typically extends intravaginal ejaculatory latency time (IELT) by a factor of 2 to 3. Real-world results vary with baseline severity, partner dynamics, and psychological factors.
Can I take Poxet every day?
No — it is an on-demand medication only. It is not suitable as a continuous daily SSRI.
Can I combine Poxet with a PDE5 inhibitor?
Yes, under medical supervision. Additive blood-pressure effects mean this combination should be trialled cautiously. Combination tablets such as Super Tadalis Sx and Super Vilitra exist specifically for this use case.
Can I drink alcohol with Poxet?
No — avoid. Alcohol sharply increases syncope, dizziness, and impaired judgement.
Will Poxet help psychological or “performance anxiety” PE?
Dapoxetine addresses the physiological side of ejaculatory reflex control. Anxiety-driven PE often benefits from combined pharmacological and behavioural approaches (stop–start technique, pelvic-floor exercises, sex-therapy).
Is Poxet addictive?
No — dapoxetine is not addictive. It has no abuse potential and does not cause dependence.
What if Poxet doesn’t work?
Give 30 mg a 4-week trial before stepping up to 60 mg. If 60 mg is still inadequate, options include behavioural therapy, topical anaesthetics (lidocaine/prilocaine cream), or specialist referral.
Dapoxetine treats premature ejaculation but does not address co-existing erectile dysfunction; for the layered indication our PE Recovery Kit (Poxet 30 mg + Vidalista 20 mg) bundles dapoxetine with tadalafil 20 mg at matched supply tiers — both molecules in one parcel, dose-matched for parallel use.
For premature ejaculation, dapoxetine pills like Poxet work systemically with onset in 1–3 hours; some patients combine an on-demand SSRI with a topical desensitiser — Lox 10 % Spray (lidocaine 10 % topical) is one of the standard topical options applied ~10 minutes pre-intercourse, with a condom recommended to minimise partner transfer.
Poxet delivers dapoxetine as a standalone on-demand option for premature ejaculation, whereas men who also need erection support can step up to Malegra FXT (sildenafil 100 / fluoxetine 40 mg), which folds a PDE5 inhibitor and a daily SSRI into one tablet.
If Poxet‘s on-demand dapoxetine alone does not extend latency far enough, pairing it with a topical anaesthetic such as Lox 2% Jelly (lidocaine 2%) adds a second, locally-acting mechanism that clinicians often use as a combination approach for premature ejaculation.
Related Alternatives
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📚 Learn more: Buy Dapoxetine Online (2026): Standalone & Combo Products — No Rx Needed
More options in Dapoxetine
Řazeno podle nedávného objemu objednávek na MedsBase — co si ostatní zákazníci v této kategorii vybírají.
| Síla | 30 mg, 60 mg, 90 mg |
|---|---|
| Množství | 60 Tablet/s, 90 Tablet/s, 120 Tablet/s, 150 Tablet/s, 200 Tablet/s |
| Pharma Form | Tablet/s |
| Manufacturer | Sunrise Remedies |
| Treatment | Erectile Dysfunction (ED) |
Poxet
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