Thiamine HCL 100
✅ Boosts energy levels
✅ Supports nerve function
✅ Improves metabolism
✅ Enhances cognitive function
✅ Promotes heart health
Thiamine HCL 100 contains Thiamine.
✓ Lékařsky ověřeno Morgan Ellis — Pharmacy Researcher · 8 years experience Last reviewed: May 2026
Rychlá odpověď
Thiamine HCL 100 (thiamine (vitamin B1) 100 mg tablet) is high-dose oral thiamine for treatment of thiamine deficiency, alcohol-related neuropathy, beriberi, and as Wernicke prophylaxis at risk patients.
- Thiamine 100 mg per tablet — full replacement strength
- Indications: alcohol use disorder, refeeding syndrome prophylaxis, beriberi, hyperemesis
- Long-term oral 100–200 mg/day for chronic deficiency or alcohol use disorder
- výrobce certifikovaného WHO-GMP
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What is Thiamine HCL 100?
Thiamine HCL 100 is high-dose oral thiamine (vitamin B1) for replacement and maintenance therapy in deficiency. Thiamine is a coenzyme essential for carbohydrate metabolism (pyruvate dehydrogenase, transketolase, alpha-ketoglutarate dehydrogenase). Deficiency causes wet beriberi (high-output cardiac failure), dry beriberi (peripheral neuropathy), and Wernicke-Korsakoff syndrome.
Indikace
- Alcohol use disorder — multi-decade chronic alcohol intake regularly causes deficiency. Long-term oral 100 mg twice daily is standard.
- Wernicke-Korsakoff syndrome — classical triad of confusion, ataxia, ophthalmoplegia in alcohol-dependent or hyperemetic patients. Acute treatment is parenteral high-dose thiamine; oral 100 mg twice daily is for prevention and post-acute maintenance.
- Beriberi — rare in food-secure populations; still seen in alcohol-dependent and severely malnourished patients
- Refeeding syndrome prophylaxis — prior to refeeding any malnourished patient (anorexia, severe undernutrition, prolonged fasting), give parenteral thiamine first then oral maintenance
- Hyperemesis gravidarum — pregnancy-related severe vomiting depletes thiamine; replacement protects against Wernicke’s
- Chronic loop diuretic use with heart failure (loop diuretics deplete thiamine; supplementation has modest evidence in advanced heart failure)
- Post-bariatric maintenance
Oral thiamine 100 mg/tablet is appropriate for prevention and chronic maintenance. In suspected acute Wernicke’s encephalopathy (confusion, ataxia, ophthalmoplegia — especially in alcohol-dependent patients, hyperemesis, post-bariatric, or refeeding) the standard is IV thiamine 500 mg three times daily for 2–3 days then 250 mg/day — oral is too slow and absorption is unreliable in this group. Never give glucose or carbohydrate to a thiamine-deficient patient before thiamine is replaced — this can precipitate Wernicke’s.
Dávka
- Maintenance in alcohol use disorder: 100 mg orally twice daily long-term
- Beriberi: 100–300 mg/day in divided doses for several weeks, then maintenance
- Refeeding prophylaxis: parenteral first; oral 100 mg twice daily during refeeding period
- Hyperemesis gravidarum: parenteral thiamine 100 mg, then oral if tolerated
- Heart failure on loop diuretic: 100 mg/day oral
Vedlejší účinky
- Generally very well tolerated — oral thiamine has an exceptional safety profile
- Anaphylaxis — rare and almost exclusively reported with parenteral thiamine, not oral
- Mild GI upset at high doses
Interakce léků
Thiamine has no significant clinically relevant drug interactions. Loop diuretics deplete thiamine but supplementation does not interfere with diuretic action.
Kontraindikace
- Hypersensitivity to thiamine (rare)
Skladování
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Často kladené dotazy
Why is thiamine so important in alcohol use?
Alcohol impairs thiamine absorption, increases urinary loss, and competes with thiamine-dependent enzymes. Long-term alcohol use causes Wernicke’s encephalopathy (acute, reversible if treated early) and Korsakoff psychosis (chronic, partially reversible). Both are essentially preventable with adequate thiamine.
Should I take thiamine if I drink heavily?
If you cannot or will not stop drinking, oral thiamine 100 mg twice daily reduces the risk of Wernicke’s — this is genuinely worth doing, even alongside ongoing drinking. Stopping alcohol is the actual treatment, but thiamine offers concrete protection while you work toward that.
What is refeeding syndrome?
Severe malnourishment depletes phosphate, magnesium, potassium, and thiamine. When carbohydrate refeeding starts, insulin surges and these intracellular shifts intensify, causing fatal arrhythmias, heart failure, and Wernicke’s. Refeeding always includes thiamine first, slow caloric increase, and electrolyte correction.
Can I take it without a deficiency?
Yes — thiamine has a wide safety margin and excess is excreted. Routine megadose without indication is pointless but harmless.
Jak rychle účinkuje?
Acute Wernicke’s (with parenteral thiamine): ophthalmoplegia improves within hours, ataxia over days, confusion over days-to-weeks. Chronic alcoholic neuropathy: slow improvement over months, often incomplete. Beriberi cardiac symptoms: hours-to-days.
Is it safe in pregnancy?
Yes — safe and important in hyperemesis gravidarum to prevent Wernicke’s. The B6 + B12 + thiamine combination in nausea-of-pregnancy management is well established.
Should I take it with B-complex?
B-complex preparations contain thiamine but at lower doses. For prevention and maintenance, B-complex is sufficient. For active deficiency or alcohol use disorder, dedicated 100 mg thiamine is preferred — the dose in standard B-complex (often 5–20 mg) is below the therapeutic threshold for these indications.
Why does my doctor give parenteral thiamine in the ED?
Acute Wernicke’s suspicion needs parenteral high-dose thiamine because (a) oral absorption is impaired in alcohol-dependent patients, (b) gut absorption is slow when minutes matter, and (c) carbohydrate-containing IV fluids are likely to be given anyway and these can precipitate Wernicke’s in deficient patients without prior thiamine cover.
Will it help my fatigue?
Only if fatigue is from documented thiamine deficiency. Most fatigue is not from thiamine; check thyroid, ferritin, vitamin D, B12, depression, sleep apnoea first.
How long should I take it?
In alcohol use disorder, lifelong supplementation is reasonable while drinking continues and for at least a year after sobriety. Otherwise, until the underlying cause (malnutrition, refeeding, hyperemesis) resolves.
Ostatní vitamíny a minerály
- Vitamin B12 1500 mcg — high-dose oral cyanocobalamin
- Walcobal Injekce — methylcobalamin IM
- Polybion Ampoule — B-complex parenteral
- Beplex Forte — B-complex oral
- Becozinc — B-complex with zinc
- Thiamine HCL 100 — thiamine 100 mg for alcohol-related neuropathy
Lékařské upozornění
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| Síla | 100 mg |
|---|---|
| Množství | 60 Tablet/s, 120 Tablet/s, 180 Tablet/s, 360 Tablet/s |
Thiamine HCL 100
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