Iverjohn
✅ Treats parasitic infections
✅ Effective against scabies
✅ Controls river blindness
✅ Combats certain parasites
✅ Prevents heartworm disease
Iverjohn contains Ivermectine.
✓ Medisch beoordeeld door Morgan Ellis — Apotheekonderzoeker · 8 jaar ervaring · Laatst beoordeeld: mei 2026
⚡ Quick Answer — What is Iverjohn?
Iverjohn is oral ivermectin tablets by Johnlee Pharmaceuticals in three strengths — 3 mg, 6 mg, and 12 mg. Standard adult dose is 200 µg/kg as a single oral dose on an empty stomach, repeated 7–14 days later for scabies and head lice. Ivermectin is the WHO-listed essential antiparasitic agent (Nobel Prize 2015) for scabies, strongyloidiasis, onchocerciasis, lymphatic filariasis, head lice, and other parasitic infections. Pre-treatment screening for Loa loa co-infection is required in patients from Central and West Africa because of encephalopathy risk.
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What is Iverjohn?
Iverjohn is oral ivermectin geproduceerd door Johnlee Pharmaceuticals Pvt Ltd, supplied in three strengths — 3 mg, 6 mg, and 12 mg tablets — to allow precise weight-based dosing without splitting tablets. Ivermectin belongs to the avermectin class of antiparasitic agents and was awarded the 2015 Nobel Prize in Physiology or Medicine for its impact on global antiparasitic therapy. It appears on the WHO Model List of Essential Medicines and is used in mass drug administration programmes against onchocerciasis and lymphatic filariasis.
How does ivermectin work?
Ivermectin binds with high selectivity to glutamate-gated chloride channels in invertebrate nerve and muscle cells. Channel opening hyperpolarises the membrane and paralyses the parasite, leading to its death. Mammals do not have glutamate-gated chloride channels in peripheral nerves, and ivermectin only weakly affects mammalian GABA-gated channels — and even then only at concentrations far above standard therapeutic plasma levels. It is this very selective targeting that gives ivermectin an excellent safety margin in humans at recommended doses.
Indicaties
| Indicatie | Standaardregime |
|---|---|
| Scabies (typical) | 200 µg/kg PO × 1, repeat at day 7–14. Combine with topical permethrin if widespread or refractory. |
| Crusted (Norwegian) scabies | 200 µg/kg on days 1, 2, 8, 9, 15 (± 22, 29) plus daily topical permethrin 5% — under specialist supervision. |
| Head lice (resistant or refractory) | 200 µg/kg PO on day 0 and day 7. Useful when permethrin / pyrethroids have failed. |
| Strongyloidiasis | 200 µg/kg PO × 1; in immunocompromised or hyperinfection, longer/repeat courses under specialist guidance. |
| Onchocerciasis (river blindness) | 150 µg/kg PO every 6–12 months until adult worm burden depleted. |
| Lymphatic filariasis | 200–400 µg/kg PO × 1, often combined with albendazole in MDA programmes. |
| Cutaneous larva migrans | 200 µg/kg PO × 1, repeat after 7 days if needed. |
Dosing — weight-based table
Ivermectin is dosed at 200 µg/kg (0.2 mg/kg) for most indications. Take on an empty stomach with water, at least 1 hour before or 2 hours after food.
| Body weight | Total dose | Tablets |
|---|---|---|
| 15–24 kg | 3 mg | 1 × 3 mg |
| 25–35 kg | 6 mg | 1 × 6 mg or 2 × 3 mg |
| 36–50 kg | 9 mg | 1 × 6 mg + 1 × 3 mg |
| 51–65 kg | 12 mg | 1 × 12 mg |
| 66–79 kg | 15 mg | 1 × 12 mg + 1 × 3 mg |
| ≥ 80 kg | 18 mg | 1 × 12 mg + 1 × 6 mg |
Bijwerkingen
Ivermectin is well tolerated. The most common reactions are due to dying parasites, not the drug itself (Mazzotti reaction in onchocerciasis):
- Headache, dizziness
- Nausea, mild abdominal discomfort
- Fatigue, drowsiness
- Muscle / joint aches
- Mild rash or transient itching
- Fever and lymph-node tenderness (in onchocerciasis — Mazzotti reaction)
Stop and seek urgent medical attention if: severe allergic reaction (angioedema, breathing difficulty), seizures, vision changes, confusion, inability to walk, or unusual bleeding/bruising.
Geneesmiddelinteracties
| Co-administered drug | Effect |
|---|---|
| Warfarine | Possible mild INR rise — monitor INR around dose. |
| Strong CYP3A4 inhibitors (clarithromycin, ketoconazole, ritonavir) | Modest plasma rise — usually clinically insignificant at single-dose ivermectin. |
| CNS depressants, benzodiazepines, alcohol | Additive sedation / dizziness possible. |
| P-glycoprotein inhibitors | Theoretical accumulation in CNS — clinically rarely an issue at standard doses. |
Pregnancy, breastfeeding, and special populations
- Zwangerschap: safety not fully established; usually avoided in the first trimester. WHO MDA programmes routinely treat the second and third trimesters; weigh case-by-case.
- Borstvoeding: excreted in breast milk in small amounts; generally compatible if treatment is needed.
- Kinderen: licensed at body weight ≥ 15 kg (typically age ≥ 5 years).
- Leverfunctiestoornis: use with caution; ivermectin is metabolised by CYP3A4 in the liver.
- HIV / immunocompromise: for strongyloidiasis, may need extended or repeated courses to clear hyperinfection risk — specialist input.
Iverjohn vs. branded ivermectin (Stromectol)
Iverjohn delivers the same active ingredient (ivermectin) at the same therapeutic doses as branded Stromectol. The pharmaceutical bioequivalence is identical — same absorption, same therapeutic effect. Iverjohn’s advantage is the three-strength range (3 / 6 / 12 mg), which allows accurate weight-based dosing without splitting tablets — branded Stromectol is most commonly only available as 3 mg.
Contra-indicaties
- Hypersensitivity to ivermectin or any excipient
- High-load Loa loa microfilaraemia (encephalopathy risk)
- Children < 15 kg body weight (efficacy and safety not established)
- Severe hepatic impairment without specialist supervision
Opslag
Store below 30 °C in the original blister, away from moisture. Out of reach of children.
Veelgestelde vragen
How quickly does Iverjohn clear scabies?
Mites are killed within hours of the dose reaching peak plasma (about 4 hours). The post-scabietic itch persists for 2–4 weeks because of immune response to retained mite antigens — that is not treatment failure. Re-dose at day 7–14 to catch newly hatched mites.
Should I take Iverjohn with food?
No. Take on an empty stomach with water — at least 1 hour before or 2 hours after a meal. Food (especially fatty meals) can increase plasma levels by ~2.5×, which is not desired at standard doses.
Iverjohn 3 mg vs 6 mg vs 12 mg — which do I need?
Use the weight table above. Most adults 51–65 kg take 12 mg; 36–50 kg take 9 mg; lighter or paediatric patients use 3 mg or 6 mg. Always reach the 200 µg/kg target, rounding up to the nearest tablet combination.
Is oral ivermectin better than topical permethrin for scabies?
For typical scabies, both work well. Topical permethrin (Permiforce Cream) is first-line for ease of use and excellent safety. Oral ivermectin is preferred when topical compliance is impossible, in institutional outbreaks, or in mobility-limited patients — and is essential in combination for crusted scabies.
Can children take Iverjohn?
Yes from body weight ≥ 15 kg (typically age ≥ 5). Below that weight use topical permethrin or seek specialist input. The 3 mg tablet is convenient for weight-based paediatric dosing.
What is Loa loa screening and do I need it?
Loa loa is a filarial worm endemic to Central and West Africa. People with very high microfilarial loads can develop fatal encephalopathy after a single ivermectin dose. Anyone born in or with prolonged residence in those regions should have a peripheral blood film looked at by an experienced parasitologist before ivermectin. Outside endemic regions screening is not routinely required.
Why don’t I just take a higher dose to be sure?
Ivermectin’s efficacy plateaus at the 200 µg/kg dose for most indications. Higher doses do not improve cure rates for scabies or strongyloidiasis but do increase the rate of side effects.
Is ivermectin safe in pregnancy?
Pregnancy data are limited. WHO MDA programmes routinely treat second and third trimester women in onchocerciasis-endemic regions, but most national guidelines avoid first-trimester use and recommend topical permethrin where possible. Discuss with your clinician.
Why was ivermectin in the news for COVID-19?
Early in vitro and underpowered observational reports led to widespread off-label use. Multiple large randomised trials (TOGETHER, ACTIV-6, COVID-OUT, PRINCIPLE) subsequently showed no clinically meaningful benefit in COVID-19 outcomes. Ivermectin is a powerful antiparasitic drug, not a COVID-19 therapy. Use only for confirmed parasitic indications.
Can I drink alcohol while taking Iverjohn?
A single small drink is unlikely to cause problems, but alcohol may add to dizziness, drowsiness, and headache, and increases liver workload during clearance. Avoid heavy alcohol use around the dose.
Other Lice & Scabies Treatments
Users running protocols that pair ivermectin with fenbendazole can save versus buying each agent separately — see our Ivermectine & Fenbendazol Combinatiepakket for the bundled option with both molecules in a single order.
Zie ook: the combination antiparasitic pack — Iverheal 12 mg paired with Wormentel 222 mg for protocol-driven multi-agent antiparasitic dosing.
- Verpin — ivermectin 6 mg tablets, alternative oral regimen
- Permiforce Cream — permethrin 5% cream — first-line scabies topical
- Perlice Cream — permethrin 1% lotion — first-line head lice
- Ivrea Shampoo — topical ivermectin 1% — for permethrin-resistant lice
- Ivrea Cream — topical ivermectin 1% — for rosacea / Demodex
Medische Disclaimer
This page is for educational purposes and is not a substitute for medical advice. Resistant or atypical infestations, persistent itch despite proper application, infested children < 2 years old, immunocompromised patients (crusted/Norwegian scabies risk), and pregnancy / breastfeeding cases need clinical assessment. Severe widespread skin infection, fever, or systemic symptoms after a course of treatment require urgent medical review. Always discuss treatment in pregnancy or breastfeeding with a clinician.
More options in Lice & Scabies Treatment
Gerangschikt op recente bestelvolumes van MedsBase — wat andere klanten in deze categorie kiezen.
| Strenght | 3 mg, 6 mg, 12 mg |
|---|---|
| Hoeveelheid | 30 Tablet/s, 60 Tablet/s, 90 Tablet/s, 180 Tablet/s, 400 Tablet/s, 800 Tablet/s |
2 beoordeling voor Iverjohn
| 5 sterren | 100% | |
| 4 sterren | 0% | |
| 3 sterren | 0% | |
| 2 sterren | 0% | |
| 1 ster | 0% |
Iverjohn
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Très bon médicament que je conseille pour un déparasitage.
Always a Great product multiple uses !!!
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Amazing customer service!!!